Polyclonal Dissemination of OXA-232 Carbapenemase- Producing Klebsiella pneumoniae, France, 2013-2021

During 2013-2021, increased prevalence of oxacil-linase 232-producing Enterobacterales was observed in France, mostly driven by its emergence in Klebsiella pneumoniae. Whole-genome sequencing identified that oxacillinase 232-producing K. pneumoniae belonged to 14 sequence types (STs), among which 2 polyclonal high -risk clones, ST-231 and ST-2096, were overrepresented.

Automated summary

During 2013-2021, there was an increase in the prevalence of oxacillinase 232-producing Enterobacterales in France, mainly driven by the emergence of Klebsiella pneumoniae. Whole-genome sequencing identified 14 sequence types (STs) of oxacillinase 232-producing K. pneumoniae, with ST-231 and ST-2096 being the most prevalent high-risk clones.