Radiation therapy for squamous cell cancer of the skin in a patient with xeroderma pigmentosum

Xeroderma Pigmentosum is an autosomal recessive disease characterized by increased sensitivity to ultraviolet radiation. Adjuvant radiotherapy (RT) is an important locoregional treatment modality for high-risk skin squamous cell cancers (SCCs). We present a case of an adult with high-risk skin SCC treated with standard adjuvant RT and followed-up for >4 years with acceptable side effects.

Automated summary

Xeroderma Pigmentosum is a hypersensitivity to ultraviolet radiation, and adjuvant radiotherapy is an effective treatment for high-risk skin squamous cell cancers.