Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles

Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.

Automated summary

This study reports the self-assembly of hetero-nanoparticles composed of a conjugate with folic acid as the targeting agent and another conjugate with paclitaxel as the active agent. The hetero-nanoparticles with varying percentages of folic acid conjugates are characterized, and their biological activity is determined.