Polysaccharides-Based Injectable Hydrogels: Preparation, Characteristics, and Biomedical Applications

Polysaccharides-based injectable hydrogels are a unique group of biodegradable and biocompatible materials that have shown great potential in the different biomedical fields. The biomolecules or cells can be simply blended with the hydrogel precursors with a high loading capacity by homogenous mixing. The different physical and chemical crosslinking approaches for preparing polysaccharide-based injectable hydrogels are reviewed. Additionally, the review highlights the recent work using polysaccharides-based injectable hydrogels as stimuli-responsive delivery vehicles for the controlled release of different therapeutic agents and viscoelastic matrix for cell encapsulation. Moreover, the application of polysaccharides-based injectable hydrogel in regenerative medicine as tissue scaffold and wound healing dressing is covered.

Automated summary

Polysaccharides-based injectable hydrogels are promising materials in biomedicine due to their biodegradability and biocompatibility. They can be used as delivery vehicles for therapeutic agents, viscoelastic matrices for cell encapsulation, and tissue scaffolds for regenerative medicine.