Aryl/aryl diazoalkanes in rhodium(II)-catalyzed rearrangements of sulfur ylides

Sigmatropic rearrangement reactions are of prime interest in the construction of small complex molecules and find widespread application in drug discovery and natural product synthesis. Herein, we report on the application of aryl/aryl diazoalkanes in rhodium-catalyzed sigmatropic rearrangement reactions of allyl sulfides. Overall, a broad variety of different allyl sulfides and different aryl/aryl diazoalkanes were compatible and the desired products were obtained in high yield.

Automated summary

Sigmatropic rearrangement reactions are widely used in drug discovery and natural product synthesis for constructing small complex molecules. In this study, we applied aryl/aryl diazoalkanes in rhodium-catalyzed sigmatropic rearrangement reactions of allyl sulfides, and achieved high yields of desired products with compatibility for various allyl sulfides and diazoalkanes.