期刊
VESTNIK TRANSPLANTOLOGII I ISKUSSTVENNYH ORGANOV
卷 24, 期 4, 页码 145-151出版社
FEDERAL RESEARCH CENTER TRANSPLANTOLOGY & ARTIFICIAL ORGANS V I SHUMAKOV
DOI: 10.15825/1995-1191-2022-4-145-151
关键词
heart; left ventricle; coronary arteries; myocardial contractility; arterial compression; coronary circulation
This work is a scientific and educational analytical review that highlights the role of myocardial contractility in regulating coronary circulation. It explains the positive impact of arterial compression on coronary hemodynamics and emphasizes the importance of understanding the mechanical relationship between the contractile and coronary systems for clinicians.
This work is a scientific and educational analytical review intended for practicing cardiologists. The purpose of the review is to draw physicians' attention to the role of myocardial contractility in the regulation of coronary circulation. We consider the fundamental phenomenon of arterial compression (squeezing) in the left ventricular (LV) wall, creating an obstruction to blood flow during cardiac systole. This phenomenon formally resembles functional coronary artery stenosis. Based on a review of the literature, the positive role of arterial compression in coronary hemodynamics is interpreted. Understanding the mechanical relationship between the contractile and coronary systems in the cardiac wall may be useful for practicing physicians when choosing treatment tactics for patients, optimizing LV bypass during heart surgeries, and improving the efficiency of adaptation of the transplanted heart.
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