THE TRANSFORMATION OF BENZIMIDAZOLES INTO FLUORINATED PYRROLES VIA CYCLOADDITION REACTIONS OF BENZIMIDAZOLIUM N-YLIDES

New highly substituted pyrroles with fluorine atoms in their structure were obtained through an improved twostage procedure starting from 1-(4-fluorobenzyl)benzimidazole, bromoacetonitrile and electron-deficient alkynes via 1,3-dipolar cycloaddition of benzimidazolium N-ylides. The structures of new fluorine-substituted pyrroles were proved by IR and NMR spectroscopy and confirmed by X-Ray analysis.

Automated summary

New highly substituted pyrroles with fluorine atoms in their structure were synthesized through an improved two-step procedure. The structures of the fluorine-substituted pyrroles were confirmed by IR and NMR spectroscopy and X-Ray analysis.