期刊
STEM CELLS INTERNATIONAL
卷 2016, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2016/5797521
关键词
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资金
- MRC [MR/K024043/1]
- BHF Cambridge Centre of Excellence [RE/13/6/30180]
- EU-FP7 project BLUEPRINT [282510]
- MRC [MR/K024043/1] Funding Source: UKRI
- Medical Research Council [MR/K024043/1] Funding Source: researchfish
Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compartment and the deriving clinical implications.
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