3.8 Article

Epigenetic Inheritance: Impact for Biology and Society-recent progress, current questions and future challenges

期刊

ENVIRONMENTAL EPIGENETICS
卷 8, 期 1, 页码 -

出版社

OXFORD UNIV PRESS
DOI: 10.1093/eep/dvac021

关键词

meeting report; epigenetics; epigenetic inheritance; transgenerational inheritance

资金

  1. University of Zurich
  2. ETH Zurich
  3. John Templeton Foundation
  4. Socorex Swiss
  5. Dovetails Genomics
  6. Vitaris
  7. Swiss National Science Foundation [31003A_175742/1]
  8. National Centre of Competence in Research RNA & Disease - Swiss National Science Foundation [182880/Phase 2, 205601/Phase 3]
  9. ETH [ETH-10 15-2, ETH-17 13-2]
  10. European Union [848158]
  11. Escher Family Fund
  12. ETH Postdoctoral Fellow [20-1 FEL-28]
  13. Swiss National Science Foundation (SNF) [31003A_175742] Funding Source: Swiss National Science Foundation (SNF)

向作者/读者索取更多资源

This article summarizes the research presented at the symposium on epigenetic inheritance and discusses the important questions, perspectives, and challenges for the field in the future.
Epigenetic inheritance has emerged as a new research discipline that aims to study the mechanisms underlying the transmission of acquired traits across generations. Such transmission is well established in plants and invertebrates but remains not well characterized and understood in mammals. Important questions are how life experiences and environmental factors induce phenotypic changes that are passed to the offspring of exposed individuals, sometimes across several successive generations, what is the contribution of germ cells and what are the consequences for health and disease. These questions were recently discussed at the symposium Epigenetic Inheritance: Impact for Biology and Society organized every 2years in Zurich, Switzerland. This review provides a summary of the research presented during the symposium and discusses current important questions, perspectives and challenges for the field in the future.

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