期刊
JOURNAL OF TISSUE ENGINEERING
卷 13, 期 -, 页码 -出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/20417314221144714
关键词
Enthesis; tendon; ligament; tissue engineering
资金
- National Natural Science Foundation of China [82272504, 82072456]
- National Key R&D Program of China [2018YFB1105100]
- Department of Science and Technology of Jilin Province, P.R.C [YDZJ202201ZYTS131, YDZJ20 2201ZYTS129, 202201ZYTS505, 20220204119YY, 20220 401084YY, 20210101321JC, 20210204104YY, 20200201 448JC, 20200403086SF, 20200201453JC, 20200404202YY]
- Department of Finance in Jilin province [2020SCZT037, 2019SCZT031]
- Jilin Province Development and Reform Commission, P.R.C [2018C010, 2022C043-5]
- Interdisciplinary Integration and Cultivation Project of Jilin University [JLUXKJC2020307]
This review discusses recent advances in enthesis tissue engineering, particularly the use of biological scaffolds, and provides perspectives on future directions in this field.
Enthesis, the interfacial tissue between a tendon/ligament and bone, exhibits a complex histological transition from soft to hard tissue, which significantly complicates its repair and regeneration after injury. Because traditional surgical treatments for enthesis injury are not satisfactory, tissue engineering has emerged as a strategy for improving treatment success. Rapid advances in enthesis tissue engineering have led to the development of several strategies for promoting enthesis tissue regeneration, including biological scaffolds, cells, growth factors, and biophysical modulation. In this review, we discuss recent advances in enthesis tissue engineering, particularly the use of biological scaffolds, as well as perspectives on the future directions in enthesis tissue engineering.
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