相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction
Daniel Grau et al.
NATURE COMMUNICATIONS (2021)
Structural basis for PRC2 engagement with chromatin
Eleanor Glancy et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2021)
mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution
Christopher M. Weber et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)
Engaging chromatin: PRC2 structure meets function
Paul Chammas et al.
BRITISH JOURNAL OF CANCER (2020)
Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters
Unmesh Jadhav et al.
MOLECULAR CELL (2020)
The SWI/SNF complex in cancer - biology, biomarkers and therapy
Priya Mittal et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
Anne Laugesen et al.
MOLECULAR CELL (2019)
Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity
Elisa Lavarone et al.
NATURE COMMUNICATIONS (2019)
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism
Andrea Piunti et al.
SCIENCE ADVANCES (2019)
Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity
Jonas Westergaard Hojfeldt et al.
MOLECULAR CELL (2019)
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Roberta Ragazzini et al.
NATURE COMMUNICATIONS (2019)
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
Wensheng Zhang et al.
CELL STEM CELL (2019)
Genomic Characterization of Differentiated Thyroid Carcinoma
Young Shin Song et al.
ENDOCRINOLOGY AND METABOLISM (2019)
Expression of EZH2 is associated with poor outcome in colorectal cancer
Zhuanpeng Chen et al.
ONCOLOGY LETTERS (2018)
Clinical utility of EZH1 mutations in the diagnosis A Check for of follicular-patterned thyroid tumors
Chan Kwon Jung et al.
HUMAN PATHOLOGY (2018)
Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2
Chul-Hwan Lee et al.
MOLECULAR CELL (2018)
Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding
Siming Chen et al.
MOLECULAR CELL (2018)
Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin
Chul-Hwan Lee et al.
MOLECULAR CELL (2018)
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
Eric Conway et al.
MOLECULAR CELL (2018)
Capturing the Onset of PRC2-Mediated Repressive Domain Formation
Ozgur Oksuz et al.
MOLECULAR CELL (2018)
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
Simon Poepsel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
Simon Poepsel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors
Matthew Bratkowski et al.
SCIENTIFIC REPORTS (2018)
Regulation of embryonic haematopoietic multipotency by EZH1
Linda T. l Vo et al.
NATURE (2018)
Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states
Cigall Kadoch et al.
NATURE GENETICS (2017)
EZH2 alterations in follicular lymphoma: biological and clinical correlations
S. Huet et al.
BLOOD CANCER JOURNAL (2017)
Genome Regulation by Polycomb and Trithorax: 70 Years and Counting
Bernd Schuettengruber et al.
CELL (2017)
Divergent Requirements for EZH1 in Heart Development Versus Regeneration
Shanshan Ai et al.
CIRCULATION RESEARCH (2017)
Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas
Davide Calebiro et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape
Robert Liefke et al.
MOLECULAR CELL (2016)
EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells
Malte Beringer et al.
MOLECULAR CELL (2016)
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
George P. Souroullas et al.
NATURE MEDICINE (2016)
Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration
Melanie von Schimmelmann et al.
NATURE NEUROSCIENCE (2016)
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2
Neil Justin et al.
NATURE COMMUNICATIONS (2016)
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
Daniel Zingg et al.
NATURE COMMUNICATIONS (2015)
A687V EZH2 Is a Driver of Histone H3 Lysine 27 ( H3K27) Hypertrimethylation
Heidi M. Ott et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Pathology of Follicular Lymphoma
Katsuyoshi Takata et al.
JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY (2014)
EZH2 mutations are frequent and represent an early event in follicular lymphoma
Csaba Boedoer et al.
BLOOD (2013)
Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin
Jinsook Son et al.
GENES & DEVELOPMENT (2013)
Nucleosome Remodeling and Epigenetics
Peter B. Becker et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Ezh1 Is Required for Hematopoietic Stem Cell Maintenance and Prevents Senescence-like Cell Cycle Arrest
Isabel Hidalgo et al.
CELL STEM CELL (2012)
Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse Heart
Aibin He et al.
CIRCULATION RESEARCH (2012)
SWI/SNF Chromatin-remodeling Factors: Multiscale Analyses and Diverse Functions
Ghia Euskirchen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
Michael T. McCabe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3 Lysine 27 Methylation
Wen Yuan et al.
SCIENCE (2012)
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
Damian B. Yap et al.
BLOOD (2011)
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
Elena Ezhkova et al.
GENES & DEVELOPMENT (2011)
Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
Frank W. Schmitges et al.
MOLECULAR CELL (2011)
The Polycomb complex PRC2 and its mark in life
Raphael Margueron et al.
NATURE (2011)
Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation
Boris G. Wilson et al.
CANCER CELL (2010)
Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells
Elena Ezhkova et al.
CELL (2009)
Role of the polycomb protein EED in the propagation of repressive histone marks
Raphael Margueron et al.
NATURE (2009)
Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
Raphael Margueron et al.
MOLECULAR CELL (2008)
EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency
Xiaohua Shen et al.
MOLECULAR CELL (2008)
A model for transmission of the H3K27me3 epigenetic mark
Klaus H. Hansen et al.
NATURE CELL BIOLOGY (2008)
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
R Cao et al.
MOLECULAR CELL (2004)
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
AP Bracken et al.
EMBO JOURNAL (2003)
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
A Kuzmichev et al.
GENES & DEVELOPMENT (2002)
Role of histone H3 lysine 27 methylation in polycomb-group silencing
R Cao et al.
SCIENCE (2002)
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal polycomb sites
B Czermin et al.
CELL (2002)
The polycomb group protein EZH2 is involved in progression of prostate cancer
S Varambally et al.
NATURE (2002)
分享论文
