Genetic Implications of Male-Reproductive-Health-Associated Comorbidities

Male infertility is a common problem. There is growing evidence that infertile men may harbor significant illness and disease. Many of the genetic causes of male fertility have implications on other systemic illnesses. This review aims to discuss various genetic conditions and gene mutations and alterations associated with male infertility and evidence for associated systemic conditions. These findings highlight the importance of a thorough workup in men presenting for a fertility assessment.

Automated summary

Male infertility is a common problem, and infertile men may have significant illnesses. The genetic causes of male infertility also have implications on other systemic diseases. Thorough examinations are important for men seeking fertility assessments.