期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 4, 期 48, 页码 8016-8024出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6tb02259f
关键词
-
资金
- National Natural Science Foundation of China [51433007, 51503125]
- China Postdoctoral Science Foundation [2015M580791]
A new class of hydrogels distinguished by electro-conductivity and high hemo-compatibility, which resemble biological tissues, are promising candidates for a plethora of biomedical applications. This work describes the design of highly elastic and biocompatible hydrogels using polypyrrole (PPy) as the conductivity media. The bio-inspired design of heparin-mimicking sodium alginate (HMSA) combined with tough alginate/polyacrylamide (PAM) is selected to form chemical and physical cross-linked binary hydrogel networks, while the incorporation of interfacial polymerized PPy endows the hydrogels with electro-conductivity. The resulting hydrogels exhibit a mesh-like hierarchical structure with excellent mechanical strength; moreover, the hydrogels show greatly enhanced electro-conductivity (up to 0.63 S m(-1)). In addition, due to the presence of the unique heparin-mimicking structure, the hydrogels possess a desirable anticoagulant ability and biocompatibility demonstrated via antithrombotic evaluations together with cell culture observations. The facile synthesis of HMSA/PAM/PPy hydrogels and their robust physical, chemical and biological performance make them attractive components for the future generation of biosensors and bioelectrodes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据