期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 4, 期 7, 页码 1337-1342出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5tb02726h
关键词
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资金
- ANR (Agence Nationale pour la Recherche) [I SIMI 10]
Multifunctionalized porous silicon nanoparticles (pSiNPs), containing the novel Ru(II) complex-photosensitizer, the polyethylene glycol moiety, and mannose molecules as cancer targeting ligands, are constructed and showcased for application in near infrared (NIR) light-responsive photodynamic therapy (PDT) and imaging of cancer. Exposure to NIR light leads to two-photon excitation of the Ru(II)-complex which allows efficient simultaneous cancer-imaging and targeted PDT therapy with the functionalized biodegradable pSiNP nanocarriers.
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