☆ 3.8 Article

Cerebrospinal fluid and peripheral blood proteomics in Traumatic Spinal Cord Injury: A prospective pilot study

BRAIN AND SPINE (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Clinical Neurology

Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury

Tobias Zrzavy et al.

Summary: This study provides a detailed characterization of inflammatory responses and oxidative tissue injury in human traumatic spinal cord injury lesions. It reveals that ongoing inflammatory responses and neurotoxicity could lead to sustained neuronal damage long after the initial trauma, potentially impacting the response to rehabilitation and recovery in patients.

BRAIN (2021)

添加到收藏夹

Review Critical Care Medicine

Blood-Spinal Cord Barrier in Spinal Cord Injury: A Review

Lin-Yu Jin et al.

Summary: The blood-spinal cord barrier is a crucial barrier that prevents toxins, blood cells, and pathogens from entering the spinal cord, and its disruption plays a key role in the progression of spinal cord injury pathology. Repairing this disruption could alleviate the damage caused by SCI.

JOURNAL OF NEUROTRAUMA (2021)

添加到收藏夹

Review Clinical Neurology

Inflammatory Response to Spinal Cord Injury and Its Treatment

Xiangyu Liu et al.

Summary: Spinal cord injury is classified into primary and secondary injury, with the inflammatory response from secondary injury becoming a main focus of research; in recent years, the complex pathophysiologic mechanism has been gradually unveiled, leading to an upgrade in treatment methods, with neuroprotective agents and nerve regeneration agents commonly used in treatment.

WORLD NEUROSURGERY (2021)

添加到收藏夹

Article Clinical Neurology

Pathophysiology of Spinal Cord Injury

Laureen D. Hachem et al.

NEUROSURGERY CLINICS OF NORTH AMERICA (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

The Glymphatic System (En)during Inflammation

Frida Lind-Holm Mogensen et al.

Summary: The glymphatic system is a fluid-transport system in the brain that plays a role in neurological diseases and neuroinflammation. It facilitates waste clearance in the brain, requires fluid exchange between perivascular spaces and the neuropil, and transports fluid back to the vasculature through lymphatic vessels.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Biochemical Research Methods

Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury

Michael A. Skinnider et al.

Summary: The research utilized targeted proteomic analyses on cerebrospinal fluid and serum samples from acute SCI patients and a large animal model, identifying protein biomarkers of injury severity and recovery, and establishing a prognostic model of neurological improvement. By conducting cross-species proteomic analyses, the study dissected evolutionarily conserved and divergent aspects of the SCI response, and validated the abundance of glial fibrillary acidic protein in cerebrospinal fluid as a biochemical outcome measure.

MOLECULAR & CELLULAR PROTEOMICS (2021)

添加到收藏夹

Article Critical Care Medicine

Possible Strategies to Optimize a Biomarker Discovery Approach to Correlate with Neurological Outcome in Patients with Spinal Cord Injury: A Pilot Study

Mercedes Fernandez et al.

JOURNAL OF NEUROTRAUMA (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Early CSF Biomarkers and Late Functional Outcomes in Spinal Cord Injury. A Pilot Study

Rita Capirossi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Clinical Neurology

Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms

Arsalan Alizadeh et al.

FRONTIERS IN NEUROLOGY (2019)

添加到收藏夹

Article Critical Care Medicine

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care

Philip Dyhrfort et al.

JOURNAL OF NEUROTRAUMA (2019)

添加到收藏夹

Article Critical Care Medicine

Predicting Injury Severity and Neurological Recovery after Acute Cervical Spinal Cord Injury: A Comparison of Cerebrospinal Fluid and Magnetic Resonance Imaging Biomarkers

Turker Dalkilic et al.

JOURNAL OF NEUROTRAUMA (2018)

添加到收藏夹

Editorial Material Orthopedics

Classifications In Brief: American Spinal Injury Association (ASIA) Impairment Scale

Timothy T. Roberts et al.

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2017)

添加到收藏夹

Article Critical Care Medicine

A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury

Femke Streijger et al.

JOURNAL OF NEUROTRAUMA (2017)

添加到收藏夹

Article Critical Care Medicine

Cerebrospinal Fluid Biomarkers To Stratify Injury Severity and Predict Outcome in Human Traumatic Spinal Cord Injury

Brian K. Kwon et al.

JOURNAL OF NEUROTRAUMA (2017)

添加到收藏夹

Review Neurosciences

How and why do T cells and their derived cytokines affect the injured and healthy brain?

Anthony J. Filiano et al.

NATURE REVIEWS NEUROSCIENCE (2017)

添加到收藏夹

Review Neurosciences

Inflammogenesis of Secondary Spinal Cord Injury

M. Akhtar Anwar et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2016)

添加到收藏夹

Article Clinical Neurology

Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome

Jens Kuhle et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)

添加到收藏夹

Review Neurosciences

The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury

Jan M. Schwab et al.

EXPERIMENTAL NEUROLOGY (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

Erika Assarsson et al.

PLOS ONE (2014)

添加到收藏夹

Article Clinical Neurology

Structural biomarkers in the cerebrospinal fluid within 24 h after a traumatic spinal cord injury: a descriptive analysis of 16 subjects

M. H. Pouw et al.

SPINAL CORD (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood

Martin Lundberg et al.

NUCLEIC ACIDS RESEARCH (2011)

添加到收藏夹

Article Critical Care Medicine

Cerebrospinal Fluid Inflammatory Cytokines and Biomarkers of Injury Severity in Acute Human Spinal Cord Injury

Brian K. Kwon et al.

JOURNAL OF NEUROTRAUMA (2010)

添加到收藏夹

Article Clinical Neurology

The cellular inflammatory response in human spinal cords after injury

Jennifer C. Fleming et al.

BRAIN (2006)

添加到收藏夹

Article Clinical Neurology

Early expression and cellular localization of proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α in human traumatic spinal cord injury

LQ Yang et al.

SPINE (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.