☆ 4.8 Article

How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2

NANOSCALE (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemical Research Methods

Lateral flow-based nucleic acid detection of SARS-CoV-2 using enzymatic incorporation of biotin-labeled dUTP for POCT use

Saloni Agarwal et al.

Summary: The COVID-19 pandemic underscores the necessity of developing ASSURED POCT technology. LAMP-LFA represents a highly sensitive and specific method for nucleic acid amplification, particularly in detecting SARS-CoV-2 N gene. This approach offers quick, accurate detection of the virus within a short timeframe.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

添加到收藏夹

Article Biophysics

An ultrasensitive molecularly imprinted polymer-based electrochemical sensor for the determination of SARS-CoV-2-RBD by using macroporous gold screen-printed electrode

Mahmoud Amouzadeh Tabrizi et al.

Summary: A novel molecularly imprinted polymer-based electrochemical sensor has been developed for the determination of SARS-CoV-2-RBD. The fabricated sensor showed high selectivity, sensitivity, and stability in detecting SARS-CoV-2-RBD in saliva samples. The sensor exhibited a good response in a concentration range of 2.0 to 40.0 pg mL(-1) with a low detection limit of 0.7 pg mL(-1).

BIOSENSORS & BIOELECTRONICS (2022)

添加到收藏夹

Article Electrochemistry

Molecularly imprinte d polypyrrole base d sensor for the detection of SARS-CoV-2 spike glycoprotein

Vilma Ratautaite et al.

Summary: This study describes the use of a polypyrrole-based sensor for detecting SARS-CoV-2-S spike glycoprotein. The sensor with molecularly imprinted polymer technology shows higher sensitivity and selectivity towards the spike glycoprotein compared to a sensor without imprints. It demonstrates the potential application of molecularly imprinted MIP-Ppy-based sensors for detecting SARS-CoV-2 virus proteins.

ELECTROCHIMICA ACTA (2022)

添加到收藏夹

Review Chemistry, Analytical

Electrochemically Deposited Molecularly Imprinted Polymer-Based Sensors

Simonas Ramanavicius et al.

Summary: This review focuses on the development of molecularly imprinted polymers (MIPs) and their application in sensor design. MIP-based conducting polymers, such as polypyrrole, are frequently used in sensor design due to their unique properties. The review also provides an overview of other materials that can be molecularly imprinted and discusses methods for designing MIP-based sensing structures and transducing analytical signals. Furthermore, it explores expected new trends and horizons in the application of MIP-based structures.

SENSORS (2022)

添加到收藏夹

Article Chemistry, Analytical

Molecularly imprinted polymer based electrochemical sensor for quantitative detection of SARS-CoV-2 spike protein

Akinrinade George Ayankojo et al.

Summary: The study presents an electrochemical sensor based on a molecularly imprinted polymer receptor for quantitatively detecting the S1 subunit of the spike protein of SARS-CoV-2. It has a quick response time and low detection limit, showing promise as a point-of-care testing platform for early diagnosis of COVID-19.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Peptide epitope-imprinted polymer microarrays for selective protein recognition. Application for SARS-CoV-2 RBD protein

Zsofia Bognar et al.

Summary: This study presents a versatile approach for generating epitope-imprinted polymer-based microarrays for protein recognition on surface plasmon resonance imaging (SPRi) chips, which can rapidly screen binding kinetics of various targets, including the SARS-CoV-2 spike protein. The highly affine molecularly imprinted polymers (MIPs) developed in this study showed lower nanomolar dissociation constants for RBD, exceeding natural affinity levels and even binding SARS-CoV-2 virus particles with higher affinity.

CHEMICAL SCIENCE (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Regional and temporal coordinated mutation patterns in SARS-CoV-2 spike protein revealed by a clustering and network analysis

Surendra S. Negi et al.

Summary: SARS-CoV-2 has undergone steady mutations globally, and some of the variants may have higher infectivity and resistance to antibodies. Detecting regionally specific variants is important for treatment and vaccine development. Through cluster and network analysis of over 1.2 million spike protein sequences from 36 countries, regionally specific groups of variants were identified.

SCIENTIFIC REPORTS (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Impact of new variants on SARS-CoV-2 infectivity and neutralization: A molecular assessment of the alterations in the spike-host protein interactions

Mary Hongying Cheng et al.

Summary: In this study, the interactions between SARS-CoV-2 variants (Alpha, Beta, Gamma, and Delta) and host cells, as well as the impact on neutralizing antibodies, were investigated using computational methods and experimental assays. It was found that certain antibodies were ineffective against Beta and Delta variants, while others remained sensitive. Specific substitutions in the Delta variant enhanced binding to host cells and recognition by proteases, facilitating viral entry.

ISCIENCE (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Molecularly Imprinted Polymer Nanoparticles Enable Rapid, Reliable, and Robust Point-of-Care Thermal Detection of SARS-CoV-2

Jake McClements et al.

Summary: Rapid antigen tests are commonly used for COVID-19 population screening, but they have low sensitivity and limited functionality in different conditions. This study presents a new approach using molecularly imprinted polymer nanoparticles (nanoMIPs) as receptors for SARS-CoV-2 antigens. The nanoMIPs exhibit high affinity and can function in challenging environments. A thermal assay with nanoMIPs is developed, which enables accurate measurement of SARS-CoV-2 antigens with low detection limits and rapid validation of clinical patient samples.

ACS SENSORS (2022)

添加到收藏夹

Review Engineering, Multidisciplinary

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Aysu Yarman et al.

Summary: Since the outbreak of the COVID-19 pandemic, various methods for fast and accurate diagnosis of SARS-CoV-2 have been developed and utilized, including RT-PCR, immunoassays, CRISPR, RT-LAMP, and bio(mimetic) sensors. This article provides an overview of the applications of MIP-based sensors since the beginning of the pandemic.

BIOMIMETICS (2022)

添加到收藏夹

Article Engineering, Biomedical

The Evolution of Molecular Recognition: From Antibodies to Molecularly Imprinted Polymers (MIPs) as Artificial Counterpart

Ortensia Ilaria Parisi et al.

Summary: Molecular recognition is a useful property shared by various molecules, allowing them to play important roles in biological and pharmaceutical research, diagnostics, theranostics, therapy, and drug delivery. While antibodies have been widely used, their high production cost and time limitations have led to research on alternative molecules such as MIPs. However, further investigations are needed to address the lack of toxicity studies and limited practical applications of MIPs.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Molecularly imprinted polymers outperform lectin counterparts and enable more precise cancer diagnosis

Jilei Pang et al.

Summary: Accurate analysis of protein biomarkers' glycosylation status is important for precise and early diagnosis of cancer. This study presents a triple MIP-based plasmonic immunosandwich assay (triMIP-PISA) that can detect AFP and AFP-L3 simultaneously in serum, distinguishing hepatocellular carcinoma patients from healthy individuals.

CHEMICAL SCIENCE (2022)

添加到收藏夹

Article Biophysics

COVID-19 diagnosis - A review of current methods

Meral Yuce et al.

Summary: A fast and accurate self-testing tool for COVID-19 diagnosis is crucial for understanding the global situation and taking appropriate actions. The diagnosis tools available mainly rely on viral gene detection, human antibody detection, and viral antigen detection, with RT-PCR being the most reliable technique.

BIOSENSORS & BIOELECTRONICS (2021)

添加到收藏夹

Article Chemistry, Analytical

Out of Pocket Protein Binding-A Dilemma of Epitope Imprinted Polymers Revealed for Human Hemoglobin

Xiaorong Zhang et al.

Summary: The study utilized epitope imprinting polymers to recognize parent proteins, revealing non-specific binding between target peptides and parent proteins, as well as stronger non-specific binding of HbA to MIPs than target peptides.

CHEMOSENSORS (2021)

添加到收藏夹

Article Biophysics

Development of a portable MIP-based electrochemical sensor for detection of SARS-CoV-2 antigen

Abdul Raziq et al.

Summary: The newly developed MIP-based electrochemical sensor for detecting SARS-CoV-2 nucleoprotein shows a linear response up to 111 fM, with detection and quantification limits of 15 fM and 50 fM. This sensor has the capability to detect ncovNP in nasopharyngeal swab samples of COVID-19 positive patients, providing a new route for rapid COVID-19 diagnostic tools.

BIOSENSORS & BIOELECTRONICS (2021)

添加到收藏夹

Article Chemistry, Analytical

Simple and robust: The claims of protein sensing by molecularly imprinted polymers

Aysu Yarman et al.

Summary: A wide range of publications over the past decade have focused on Molecularly Imprinted Polymers (MIPs), with approximately 10% of these papers detailing their application in protein recognition. The straightforward synthesis of MIPs, using only a few functional monomers, allows for multi-analyte measurements and provides advantages over the complexity of proteins.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Development and Characterization of Magnetic SARS-CoV-2 Peptide-Imprinted Polymers

Beatriz Fresco-Cala et al.

Summary: Developing rapid, sensitive, and selective detection methods for SARS-CoV-2 is crucial in combating the global pandemic. In this study, magnetic molecularly imprinted polymers (MMIPs) were prepared using dopamine self-polymerization on magnetic nanoparticles, with a peptide of the viral spike protein as the imprinting template. Dopamine was chosen as the functional monomer for its high binding energy and multi-point interactions with the peptide template.

NANOMATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

SARS-CoV-2-Impedimetric Biosensor: Virus-Imprinted Chips for Early and Rapid Diagnosis

Heba A. Hussein et al.

Summary: An electrochemical sensing platform was developed for the diagnosis of COVID-19, achieving high selectivity and low detection limit targets. Its application in clinical samples provides a convenient and portable point of care, offering potential widespread use in medical settings, airports, and hotspots.

ACS SENSORS (2021)

添加到收藏夹

Review Polymer Science

Advances in Molecularly Imprinted Polymers Based Affinity Sensors (Review)

Simonas Ramanavicius et al.

Summary: This review outlines the important directions and applications of polymer-based semiconducting materials in affinity sensors, focusing on the bioanalytical application of conducting polymers such as polypyrrole and polyaniline. It also discusses advancements in polymerization techniques and analytical signal transduction methods applied in affinity sensors. Additionally, the review highlights the development and application of molecularly imprinted polymer-based structures as potential replacements for expensive affinity reagents.

POLYMERS (2021)

添加到收藏夹

Article Electrochemistry

Insights in electrosynthesis, target binding, and stability of peptide-imprinted polymer nanofilms

Giorgio Caserta et al.

Summary: This study explores the preparation of peptide-imprinted polymer nanofilms for selective recognition of human adult hemoglobin, utilizing a hierarchical approach with superior affinity and providing key mechanistic insights towards the stability of the formed MIPs.

ELECTROCHIMICA ACTA (2021)

添加到收藏夹

Article Chemistry, Analytical

Highly sensitive electrochemical determination of the SARS-COV-2 antigen based on a gold/graphene imprinted poly-arginine sensor

Tao Zhang et al.

Summary: This study proposed a simple and highly sensitive molecularly imprinted polymer sensor for detecting the nucleocapsid protein of SARS-CoV-2 by introducing gold/graphene nanohybrids to modify a screen-printed carbon electrode and using arginine as the functional monomer. By optimizing various factors, the sensor showed a wide linear range and low detection limit, demonstrating important potential for early diagnosis of COVID-19.

ANALYTICAL METHODS (2021)

添加到收藏夹

Article Virology

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2

Zhixin Liu et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

添加到收藏夹

Article Cell Biology

A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples

Viet Loan Dao Thi et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Rapid isothermal amplification and portable detection system for SARS-CoV-2

Anurup Ganguli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

Article Biochemical Research Methods

Epitope approach in molecular imprinting of antibodies

Ewa Moczko et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Intracellular Delivery and Sensing System Based on Electroplated Conductive Nanostraw Arrays

Rui Wen et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Biophysics

Cardiac Troponin T capture and detection in real-time via epitope-imprinted polymer and optical biosensing

P. Palladino et al.

BIOSENSORS & BIOELECTRONICS (2018)

添加到收藏夹

Article Biophysics

Synthesis and application of a plastic antibody in electrochemical microfluidic platform for oxytocin determination

Piyush Sindhu Sharma et al.

BIOSENSORS & BIOELECTRONICS (2018)

添加到收藏夹

Article Chemistry, Analytical

Epitope molecularly imprinted polymer coated quartz crystal microbalance sensor for the determination of human serum albumin

Xiao-Tong Ma et al.

SENSORS AND ACTUATORS B-CHEMICAL (2017)

添加到收藏夹

Article Chemistry, Analytical

An Insulin Molecularly Imprinted Electrochemical Sensor Based on Epitope Imprinting

Zhao Cheng-Jun et al.

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (2017)

添加到收藏夹

Review Chemistry, Analytical

MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing

Marcus Menger et al.

BIOSENSORS-BASEL (2016)

添加到收藏夹

Article Chemistry, Analytical

Antibody-Free Biomarker Determination: Exploring Molecularly Imprinted Polymers for Pro-Gastrin Releasing Peptide

Cecilia Rossetti et al.

ANALYTICAL CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Protein Rebinding to a Surface-Confined Imprint

Decha Dechtrirat et al.

ADVANCED FUNCTIONAL MATERIALS (2012)

添加到收藏夹

Article Chemistry, Multidisciplinary

Comparing biomimetic and biological receptors for insulin sensing

Romana Schirhagl et al.

CHEMICAL COMMUNICATIONS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Artificial antibodies for bioanalyte detection-sensing viruses and proteins

Oliver Hayden et al.

ADVANCED FUNCTIONAL MATERIALS (2006)

添加到收藏夹

Article Chemistry, Multidisciplinary

Selective protein capture by epitope imprinting

H Nishino et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

Article Electrochemistry

Electroless deposition of gold thin films on silicon for surface-enhanced infrared spectroelectrochemistry

H Miyake et al.

ELECTROCHEMISTRY COMMUNICATIONS (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.