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The meaning of life horizontal ellipsis cycles: lessons from and for safe by design studies

GREEN CHEMISTRY (2022)

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Summary: The acceptability and relevance of nanoparticles can be improved using a safer-by-design strategy. This study focuses on lanthanide oxysulfide nanoparticles and investigates their ability to absorb visible light and generate reactive oxygen species (ROS). The results show that cerium-containing oxysulfide nanoparticles produce more ROS than cerium-free nanoparticles, without causing significant inflammatory response or oxidative stress.

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Summary: Decisions about the development of new technologies or products have implications for the economy, society, and the environment. Environmental and health risk assessment, as well as sustainability assessment, provide complementary information about the consequences of these decisions. However, conflicts or synergies may arise when considering specific risks and safety in relation to long-term sustainability. A combined assessment approach is recommended to support informed decision-making and safe and sustainable design.

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ASINA Project: Towards a Methodological Data-Driven Sustainable and Safe-by-Design Approach for the Development of Nanomaterials

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Summary: This article introduces the ASINA project's Sustainable and Safe-by-Design (SSbD) methodology and its application in Nano-Enabled Products (NEPs). The methodology captures quality, safety, and sustainability criteria through a data-driven management approach. By developing highly representative NEPs value chains, the methodology helps identify and address environmental impact, techno-economic performance, functionality, and human and environmental safety at an early stage.

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Safe(r) by design guidelines for the nanotechnology industry

Araceli Sanchez Jimenez et al.

Summary: Expectations for safer and sustainable chemicals and products are increasing, and this article introduces the application of Safe(r) by Design (SbD) in nanotechnology. The SbD approach aims to assess and balance functionality, human health and safety, environmental and economic impact, and cost as early as possible in the innovation process. The article also presents guidelines on the practical application of SbD based on the experience from the EU H2020 NanoReg2 project.

NANOIMPACT (2022)

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Safe-and-Sustainable-by-Design Framework Based on a Prospective Life Cycle Assessment: Lessons Learned from a Nano-Titanium Dioxide Case Study

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INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

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Testing the Applicability of the Safe-by-Design Concept: A Theoretical Case Study Using Polymer Nanoclay Composites for Coffee Capsules

Anna Pavlicek et al.

Summary: The production and use of engineered nanomaterials and nano-enabled products are increasing rapidly, especially in food contact materials. However, there is a lack of safety information for chemical risk assessment, leading to high uncertainty in integrating safety into the innovation process early on. The study analyzed the application of the Safe-by-Design concept using nanoclay-containing polymer coffee capsules and identified challenges in information transfer and practical implementation.

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Summary: This research proposes a strategy to link the functionality of nanomaterials with safety aspects in order to foster the development of safer nanomaterial-containing products. The strategy combines functionality and safety information early in the innovation process and identifies Safe-by-Design actions to optimize both aspects. The strategy provides suggestions for balancing functionality and safety to support decision making in the innovation process.

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Commentary on Safe(r) by design implementation in the nanotechnology industry [NanoImpact 20 (2020) 100267] and Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials [NanoImpact 23 (2021) 100335]

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The SERENADE project - A step forward in the Safe by Design process of nanomaterials: Moving towards a product-oriented approach

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Summary: Recent research has focused on formalizing and standardizing the Safe by Design process of nanomaterials, but the lack of flexibility in the general strategy has shown the need for alternative approaches.

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Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials

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Summary: The manuscript discusses the integration of safe by design and sustainability through risk assessment, life cycle assessment, and economic viability evaluation. The approach results in a decision tree that integrates these elements to achieve sustainable, safe, and competitive materials, products, or services. Data gaps are highlighted as a crucial aspect affecting the reliability of the results in a case study involving nanoparticles for Li-Ion batteries.

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Assessing Sunscreen Lifecycle to Minimize Environmental Risk Posed by Nanoparticulate UV-Filters - A Review for Safer-by-Design Products (vol 8, 101, 2020)

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Life cycle based alternatives assessment (LCAA) for chemical substitution

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SERENADE: safer and ecodesign research and education applied to nanomaterial development, the new generation of materials safer by design

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JOURNAL OF INDUSTRIAL ECOLOGY (2013)

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Life cycle assessment of building materials: Comparative analysis of energy and environmental impacts and evaluation of the eco-efficiency improvement potential

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BUILDING AND ENVIRONMENT (2011)

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CHEMICAL SOCIETY REVIEWS (2010)

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Editorial Material Green & Sustainable Science & Technology

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Jo Anne Shatkin

JOURNAL OF INDUSTRIAL ECOLOGY (2008)

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Alexis Cain et al.

JOURNAL OF INDUSTRIAL ECOLOGY (2007)

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