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C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and insulin resistance in patients with diabetes mellitus type 2
D. A. de Luis et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2010)
FAAH deficiency promotes energy storage and enhances the motivation for food
C. Tourino et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
X-ray Crystallographic Analysis of α-Ketoheterocycle Inhibitors Bound to a Humanized Variant of Fatty Acid Amide Hydrolase
Mauro Mileni et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Biomarkers of Endocannabinoid System Activation in Severe Obesity
Jack C. Sipe et al.
PLOS ONE (2010)
Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1
D. Proudnikov et al.
PHARMACOGENOMICS JOURNAL (2010)
The role of the endocannabinoid system in lipogenesis and fatty acid metabolism
Roberto Vettor et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Divergent Effects of Genetic Variation in Endocannabinoid Signaling on Human Threat- and Reward-Related Brain Function
Ahmad R. Hariri et al.
BIOLOGICAL PSYCHIATRY (2009)
Radiosynthesis, in vitro and in vivo evaluation of I-123-labeled anandamide analogues for mapping brain FAAH
Leonie Wyffels et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain
Kay Ahn et al.
CHEMISTRY & BIOLOGY (2009)
Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects
P. Monteleone et al.
GENES BRAIN AND BEHAVIOR (2009)
Synthesis, In Vitro and In Vivo Evaluation, and Radiolabeling of Aryl Anandamide Analogues as Candidate Radioligands for In Vivo Imaging of Fatty Acid Amide Hydrolase in the Brain
Leonie Wyffels et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Positron emission tomography neuroimaging for a better understanding of the biology of ADHD
Luc Zimmer
NEUROPHARMACOLOGY (2009)
Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic-Pituitary-Adrenal Axis
Matthew N. Hill et al.
NEUROPSYCHOPHARMACOLOGY (2009)
Variants in the CNR1 and the FAAH Genes and Adiposity Traits in the Community
Wolfgang Lieb et al.
OBESITY (2009)
Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue
Lucia Marquez et al.
PLOS ONE (2009)
Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent
Yi Zhang et al.
PHARMACOGENOMICS (2009)
The genetic landscape of intellectual disability arising from chromosome X
Jozef Gecz et al.
TRENDS IN GENETICS (2009)
Antecedent Nonbladder Syndromes in Case-Control Study,of Interstitial Cystitis/Painful Bladder Syndrome
John W. Warren et al.
UROLOGY (2009)
Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure
Miriam Schneider
ADDICTION BIOLOGY (2008)
Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation
Michael Camilleri et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Endocannabinoid system in food intake and metabolic regulation
David Jesudason et al.
CURRENT OPINION IN LIPIDOLOGY (2008)
Targeting endocannabinoid degradation protects against experimental colitis in mice:: involvement of CB1 and CB2 receptors
Martin A. Storr et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
Cannabinoid receptors: Where they are and what they do
K. Mackie
JOURNAL OF NEUROENDOCRINOLOGY (2008)
Biological functions and metabolism of oleoylethanolamide
Clementine Thabuis et al.
LIPIDS (2008)
Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms
Christoph Buettner et al.
NATURE MEDICINE (2008)
Targeting the endocannabinoid system: to enhance or reduce?
Vincenzo Di Marzo
NATURE REVIEWS DRUG DISCOVERY (2008)
Evaluating the Association of FAAH Common Gene Variation with Childhood, Adult Severe Obesity and Type 2 Diabetes in the French Population
Emmanuelle Durand et al.
OBESITY FACTS (2008)
The cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese women
Palmiero Monteleone et al.
PSYCHONEUROENDOCRINOLOGY (2008)
Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
Timo Müller et al.
Child and Adolescent Psychiatry and Mental Health (2008)
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus
E. Soria-Gomez et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
The expression of receptors for endocannabinoids in human and rodent skeletal muscle
Paul Cavuoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
Jacqueline L. Blankman et al.
CHEMISTRY & BIOLOGY (2007)
Neural mechanisms of pelvic organ cross-sensitization
A. P. Malykhina
NEUROSCIENCE (2007)
Association study between alcoholism and endocannabinoid metabolic enzyme genes encoding fatty acid amide hydrolase and monoglyceride lipase in a Japanese population
Shinya Iwasaki et al.
PSYCHIATRIC GENETICS (2007)
The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: Studies of drug use and dependence in Caucasians
Rachel F. Tyndale et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2007)
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites
Dorit P. Jensen et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
Genetic variation in two proteins of the endocannabinoid system and their influence on body mass index and metabolism under low fat diet
J. Aberle et al.
HORMONE AND METABOLIC RESEARCH (2007)
The endogenous cannabinoid anandamide produces δ-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport
Marcello Solinas et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Critical enzymes involved in endocannabinoid metabolism
Balapal S. Basavarajappa
PROTEIN AND PEPTIDE LETTERS (2007)
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
Robert B. Innis et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
A second fatty acid amide hydrolase with variable distribution among placental mammals
Binqing Q. Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity
Matthias Blueher et al.
DIABETES (2006)
The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction
Jonathan M. Flanagan et al.
HUMAN GENETICS (2006)
Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization
EE Ustinova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit
YH Jo et al.
NEURON (2005)
Activation of the peripheral endocannabinoid system in human obesity
S Engeli et al.
DIABETES (2005)
Fatty acid amide hydrolase controls mouse intestinal motility in vivo
R Capasso et al.
GASTROENTEROLOGY (2005)
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)
JC Sipe et al.
INTERNATIONAL JOURNAL OF OBESITY (2005)
Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa
P Monteleone et al.
NEUROPSYCHOPHARMACOLOGY (2005)
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
D Osei-Hyiaman et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophrenia
Y Morita et al.
NEUROSCIENCE LETTERS (2005)
Structure and function of fatty acid amide hydrolase
MK McKinney et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2005)
The endogenous cannabinoid system protects against colonic inflammation
F Massa et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use
KP Chiang et al.
HUMAN MOLECULAR GENETICS (2004)
The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders
M van der Stelt et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Modulation of anxiety through blockade of anandamide hydrolysis
S Kathuria et al.
NATURE MEDICINE (2003)
AGA technical review on irritable bowel syndrome
DA Drossman et al.
GASTROENTEROLOGY (2002)
American gastroenterological association medical position statement: Irritable bowel syndrome
GASTROENTEROLOGY (2002)
Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling
MH Bracey et al.
SCIENCE (2002)
A missense mutation in human fatty acid amide hydrolase associated with problem drug use
JC Sipe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Cognitive functioning of long-term heavy cannabis users seeking treatment
N Solowij et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation
AA Izzo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
BF Cravatt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Localization of CB1-cannabinoid receptor immunoreactivity in the porcine enteric nervous system
A Kulkarni-Narla et al.
CELL AND TISSUE RESEARCH (2000)
The endogenous cannabinoid system and brain development
J Fernandez-Ruiz et al.
TRENDS IN NEUROSCIENCES (2000)