期刊
ABDOMINAL RADIOLOGY
卷 48, 期 2, 页码 688-693出版社
SPRINGER
DOI: 10.1007/s00261-022-03720-0
关键词
Biparametric MRI; Multiparametric MRI; Prostate cancer; Equivocal PI-RADS 3; TRUS biopsy
The purpose of this study was to compare two strategies, PSAd and lesion volume measurement, in ruling out significant prostate cancer in men with equivocal PI-RADS category 3 index lesions. The study found that the PSAd strategy performed better than the lesion volume strategy in ruling out sPCa.
Purpose To compare two strategies: Prostate-specific antigen density (PSAd) and lesion volume measurement in ruling out significant prostate cancer (sPCa) in men with equivocal Prostate Imaging Reporting and Data System (PI-RADS) category 3 index lesions on biparametric magnetic resonance imaging. Methods In total, 130 men from our database had index lesions with PI-RADS scores of 3. Prostate volume was measured using the ellipsoid method, in accordance with PI-RADS version 2.1 criteria. Index lesion volumes were also measured using the ellipsoidal formula on the diffusion-weighted imaging sequence with the highest b-value and sagittal T2 sequences. Results Among 130 men with PI-RADS category 3 index lesions, 23 (18%) had sPCa. In total, 6 of the 89 men with PSAd < 0.15 ng/mL(2) (7%) had sPCa, whereas 8 of the 49 men with index lesion volumes < 0.5 mL (16%) had sPCa. The difference was statistically significant (McNemar, p < 0.0001). Conclusion The PSAd strategy performed better than the lesion volume strategy in ruling out sPCa in men with equivocal PI-RADS category 3 index lesions.
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