☆ 4.3 Review

Efficacy and safety of carbon dioxide laser therapy compared with sham for genitourinary syndrome of menopause management: a meta-analysis of randomized clinical trials

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2023)

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Article Obstetrics & Gynecology

Laser versus sham for genitourinary syndrome of menopause: A randomised controlled trial

Ann-Sophie Page et al.

Summary: The study aimed to assess whether CO2 laser treatment is more effective than sham application in relieving symptoms in women with genitourinary syndrome of menopause (GSM). The results showed that the treatment response after 12 weeks of laser application was comparable to that of the sham applications, and no serious adverse events were reported.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2023)

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Article Psychology, Experimental

Let's go beyond the effect of: Reappraising the impact of ordinary activities on cognition

Rafael Roman-Caballero et al.

Summary: The demands of society for interventions that optimize cognitive abilities and prevent decline have led to the translation of scientific findings into practical programs. Various activities and cognitive programs have been found to have cognitive benefits. However, before drawing implications, several factors need to be considered, including the magnitude and costs of the effect, the robustness of the effect, testing causality, identifying moderator variables, and understanding the underlying mechanisms. These considerations can help researchers critically evaluate existing findings, reduce media overstatements, and potentially guide the design of new interventions.

PSICOLOGICA (2023)

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Review Urology & Nephrology

CO2-Laser therapy and Genitourinary Syndrome of Menopause: A Systematic Review and Meta-Analysis

Maurizio Filippini et al.

Summary: This study systematically reviewed the current literature on the efficacy of CO2-Laser therapy for the treatment of genitourinary syndrome of menopause (GSM). The results showed that CO2-Laser therapy can significantly reduce symptoms of Vulvo-Vaginal Atrophy (VVA) and/or GSM, and it has a good safety profile.

JOURNAL OF SEXUAL MEDICINE (2022)

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Article Obstetrics & Gynecology

CO2 laser and the genitourinary syndrome of menopause: a randomized sham-controlled trial

S. Salvatore et al.

Summary: In postmenopausal women with genitourinary syndrome of menopause, CO2 laser treatment was found to be more effective in improving dryness, dyspareunia, and sexual dysfunction compared to sham treatments.

CLIMACTERIC (2021)

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Review Urology & Nephrology

A Double-Blind Randomized Sham-Controlled Trial to Evaluate the Efficacy of Fractional Carbon Dioxide Laser Therapy on Genitourinary Syndrome of Menopause

Jason Cruff et al.

Summary: This study aimed to assess the effectiveness of fractional CO2 laser therapy for GSM through a randomized, double-blind, sham-controlled trial. The results showed no significant difference in improvement proportion between the treatment and control groups, but both groups showed significant within-group improvements in VHI and VAS. Further research is needed to determine the therapeutic effect of this novel modality.

JOURNAL OF SEXUAL MEDICINE (2021)

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Review Public, Environmental & Occupational Health

Genitourinary Syndrome of Menopause: Epidemiology, Physiopathology, Clinical Manifestation and Diagnostic

Ayane Cristine Alves Sarmento et al.

Summary: Genitourinary syndrome of menopause (GSM) is a term used to describe a collection of symptoms and signs caused by decreased estrogenic stimulation in postmenopausal women. It can significantly impact health and sexual function, with diagnosis requiring a combination of methods including medical history, questionnaires, and physical exams.

FRONTIERS IN REPRODUCTIVE HEALTH (2021)

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Article Geriatrics & Gerontology

Pilot study of fractional CO2 laser therapy for genitourinary syndrome of menopause in gynecologic cancer survivors

Allison M. Quick et al.

MATURITAS (2020)

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Article Obstetrics & Gynecology

Treatment for vaginal atrophy using microablative fractional CO2 laser: a randomized double-blinded sham-controlled trial

Purim Ruanphoo et al.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2020)

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Review Obstetrics & Gynecology

A systematic review of the efficacy and safety of vaginal estrogen products for the treatment of genitourinary syndrome of menopause

Colton Biehl et al.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2019)

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Article Health Care Sciences & Services

Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range

Dehui Luo et al.

STATISTICAL METHODS IN MEDICAL RESEARCH (2018)

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Editorial Material Obstetrics & Gynecology

Randomised controlled trials - the gold standard for effectiveness research Study design: randomised controlled trials

Eduardo Hariton et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2018)

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Review Health Care Sciences & Services

Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations

Monika Mueller et al.

BMC MEDICAL RESEARCH METHODOLOGY (2018)

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Article Geriatrics & Gerontology

CO2-laser for the genitourinary syndrome of menopause. How many laser sessions?

Stavros Athanasiou et al.

MATURITAS (2017)

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Review Obstetrics & Gynecology

Genitourinary syndrome of menopause: an overview of clinical manifestations, pathophysiology, etiology, evaluation, and management

Jason Gandhi et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2016)

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Review Geriatrics & Gerontology

Update on management of genitourinary syndrome of menopause: A practical guide

Santiago Palacios et al.

MATURITAS (2015)

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Article Health Care Sciences & Services

Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

Xiang Wan et al.

BMC MEDICAL RESEARCH METHODOLOGY (2014)

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Review Obstetrics & Gynecology

Vaginal Estrogen for Genitourinary Syndrome of Menopause A Systematic Review

David D. Rahn et al.

OBSTETRICS AND GYNECOLOGY (2014)

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Article Mathematical & Computational Biology

Adjusting for publication bias in the presence of heterogeneity

N Terrin et al.

STATISTICS IN MEDICINE (2003)

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Article Health Care Sciences & Services

Publication bias in meta-analysis: its causes and consequences

A Thornton et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2000)

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