Prevalence of Asymptomatic Mpox among Men Who Have Sex with Men, Japan, January-March 2023

Article Immunology

Evidence of Mpox Virus Infection Among Persons Without Characteristic Lesions or Rash Presenting for First Dose of JYNNEOS Vaccine-District of Columbia, August 2022

Yasmin P. Ogale et al.

Summary: We evaluated the prevalence of mpox virus in blood, pharyngeal, and rectal specimens among individuals without characteristic rash who were receiving JYNNEOS vaccine. Our findings suggest that risk-based screening for mpox in individuals without skin lesions or rash using pharyngeal swabs, rectal swabs, and/or blood may have limited utility.

CLINICAL INFECTIOUS DISEASES (2023)

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Article Immunology

The Roles of Unrecognized Monkeypox Cases, Contact Isolation and Vaccination in Determining Epidemic Size in Belgium: A Modeling Study

Christophe Van Dijck et al.

Summary: This study used a network model to simulate a monkeypox epidemic among men who have sex with men. The findings suggest that unidentified infections play a crucial role in the epidemic, and vaccinating individuals at highest risk of infection is more effective in reducing the size of the epidemic compared to post-exposure vaccination of sexual partners.

CLINICAL INFECTIOUS DISEASES (2023)

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Letter Infectious Diseases

Asymptomatic monkeypox infection: a call for greater control of infection and transmission

Abdullah Reda et al.

LANCET MICROBE (2023)

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Article Public, Environmental & Occupational Health

Possible Undetected Mpox Infection Among Persons Accessing Homeless Services and Staying in Encampments — San Francisco, California, October–November 2022

Caroline J. Waddell et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2023)

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Letter Medicine, General & Internal

Detection of Monkeypox Virus in Anorectal Swabs From Asymptomatic Men Who Have Sex With Men in a Sexually Transmitted Infection Screening Program in Paris, France

Valentine Marie Ferre et al.

ANNALS OF INTERNAL MEDICINE (2022)

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Article Biochemistry & Molecular Biology

Retrospective detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium

Irith De Baetselier et al.

Summary: The magnitude of the 2022 monkeypox virus outbreak has exceeded any previous outbreak, and undiagnosed infections may be driving the epidemic. A study found four men attending a Belgian sexual health clinic to be infected with monkeypox. One man had a painful rash while the other three were asymptomatic, but their infections were confirmed through clinical examination. These findings suggest that undiagnosed cases of monkeypox could contribute to the transmission and scale of the 2022 outbreak.

NATURE MEDICINE (2022)

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Review Immunology

Potentially Asymptomatic Infection of Monkeypox Virus: A Systematic Review and Meta-Analysis

Prakasini Satapathy et al.

Summary: This meta-analysis found that many people infected with the monkeypox virus are asymptomatic and difficult to detect. Therefore, prompt detection and appropriate management of these asymptomatic cases are of utmost importance to global public health.

VACCINES (2022)

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Letter Infectious Diseases

Mpox screening in high- risk populations finds no asymptomatic cases

Christophe Van Dijck et al.

LANCET MICROBE (2022)

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Article Infectious Diseases

Isolation of viable monkeypox virus from anal and urethral swabs, Italy, May to July 2022

Davide Moschese et al.

Summary: The study found that the monkeypox virus could be detected in anal and urethral samples from confirmed cases, with actively-replicating virus still present within 7 days from symptom onset. It was also discovered that asymptomatic secondary cases may support a potential sexual transmission hypothesis.

EUROSURVEILLANCE (2022)

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Article Infectious Diseases

Modified self-obtained pooled sampling to screen for Chlamydia trachomatis and Neisseria gonorrhoeae infections in men who have sex with men

Naokatsu Ando et al.

Summary: This study found that pooled sample testing using gargle samples had high consistency with single-site sample testing in screening for STI infections in asymptomatic men who have sex with men. The results suggest that gargle samples can be a suitable part of pooled samples for screening for Chlamydia trachomatis and Neisseria gonorrhoeae.

SEXUALLY TRANSMITTED INFECTIONS (2021)

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Article Biochemical Research Methods

Species-specific differentiation of variola, monkeypox, and varicella-zoster viruses by multiplex real-time PCR assay

Rinat A. Maksyutov et al.

JOURNAL OF VIROLOGICAL METHODS (2016)

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Prevalence of Asymptomatic Mpox among Men Who Have Sex with Men, Japan, January-March 2023

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