Fatal Necrotizing Enterocolitis in Neonate Caused by Cronobacter sakazakii Sequence Type 64 Strain of CRISPR Sublineage b

We report fatal neonatal necrotizing enterocolitis in China caused by Cronobacter sakazakii capsular pro-file K1:CA1, sequence type 64, and CRISPR type 197. Phylodynamic analyses indicated that the strain origi-nated from the ancient, widespread, and antimicrobial drug-sensitive CRISPR sublineage b. Enhanced sur-veillance and pathogenesis research on this organism are required.

Automated summary

We report a case of fatal neonatal necrotizing enterocolitis in China caused by a specific profile of Cronobacter sakazakii. Phylodynamic analysis revealed that the strain originated from a widespread and antimicrobial drug-sensitive sublineage of CRISPR. Enhanced surveillance and pathogenesis research on this organism are needed.