3.9 Article

Actigraphy Analysis of Sleep Associates with Salivary IL-6 Concentration in Institutionalized Older Individuals

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Knee osteoarthritis accelerates amyloid beta deposition and neurodegeneration in a mouse model of Alzheimer's disease

Deepak Prasad Gupta et al.

Summary: This study investigated the relationship between knee osteoarthritis (OA) and Alzheimer's disease (AD) by using an AD mouse model. The researchers induced knee OA in control and AD mice and analyzed the effects on brain histology and neuroinflammation. The results showed that OA increased inflammatory cytokine levels, beta-amyloid plaque deposition, and neuronal loss in AD mice, suggesting that knee OA could accelerate dementia progression in AD.

MOLECULAR BRAIN (2023)

Article Pharmacology & Pharmacy

Levetiracetam attenuates diabetes-associated cognitive impairment and microglia polarization by suppressing neuroinflammation

Yun-yun Zhang et al.

Summary: Levetiracetam improves cognitive impairment in streptozotocin-induced diabetic rats by suppressing microglia activation. In vitro experiments suggest that levetiracetam inhibits microglia polarization via the JNK/MAPK/NF-kappa B signaling pathway.

FRONTIERS IN PHARMACOLOGY (2023)

Article Geriatrics & Gerontology

Associations between saliva and plasma cytokines in cognitively normal, older adults

Georgia M. Parkin et al.

Summary: This study found that inflammatory markers in saliva are associated with those found in circulation, suggesting shared inflammatory mechanisms between these two fluids. The higher levels of cytokines measured in saliva suggest that it might represent a better peripheral fluid to gauge inflammatory processes. Additionally, the research revealed robust sex differences in several salivary cytokines, indicating potential implications for their use as disease biomarkers in the elderly and their association with sex differences in the prevalence of age-related conditions.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2023)

Article Clinical Neurology

IL-6 and IL-8 are likely associated with psychological status in treatment naive general population

Xiao Liu et al.

Summary: This study investigated the inflammatory biomarker profiles of psychological treatment-naive individuals and found that levels of IL-6 and IL-8 were positively correlated with symptoms of depression, suggesting they may play a role in the pathogenesis of psychological disorders. However, these associations were not significant after multiple testing. Larger and longitudinal studies are needed to confirm these findings.

JOURNAL OF AFFECTIVE DISORDERS (2022)

Article Clinical Neurology

Interaction effect of the serum interleukin-6 level and anxiety on the 12-week pharmacotherapeutic responses of patients with depressive disorders

Wonsuk Choi et al.

Summary: The baseline serum IL-6 level and severity of anxiety symptoms can predict the outcome of antidepressant treatment. Patients with low IL-6 levels and mild anxiety symptoms are more likely to experience remission of depression.

JOURNAL OF AFFECTIVE DISORDERS (2022)

Article Neurosciences

The relationship between pulse pressure with plasma PCSK9 and interleukin-6 among patients with acute ischemic stroke and dyslipidemia

Chen-Shu Chang et al.

Summary: This study aimed to investigate the role of plasma PCSK9 and IL-6 in acute ischemic stroke with dyslipidemia. The results showed that plasma PCSK9 levels were associated with the low pulse pressure subgroup, while IL-6 was associated with the high pulse pressure subgroup. Controlling dyslipidemia is necessary for stroke patients with high pulse pressure.

BRAIN RESEARCH (2022)

Article Geriatrics & Gerontology

Associations of sleep timing and time in bed with dementia and cognitive decline among Chinese older adults: A cohort study

Rui Liu et al.

Summary: Sleep timing and time in bed are associated with the risk of dementia and cognitive decline in older adults, with long time in bed and early sleep timing being linked to higher risk and greater decline in cognitive function.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2022)

Article Clinical Neurology

Accuracy of Actigraphy Compared to Concomitant Ambulatory Polysomnography in Narcolepsy and Other Sleep Disorders

Anniina Alakuijala et al.

Summary: Actigraphy provides longitudinal sleep data and is an inexpensive method for measuring sleep. This study compared actigraphy to ambulatory polysomnography in different sleep-disordered patients. Results showed good accuracy but poor precision in measuring sleep time, efficiency, and latency, with actigraphy tending to overestimate sleep time and underestimate it in patients with obstructive sleep apnea and narcolepsy, respectively. Overall, actigraphy is reliable for measuring sleep time, but its effectiveness may decrease in subjects with low sleep efficiencies.

FRONTIERS IN NEUROLOGY (2021)

Review Medicine, General & Internal

Salivary Inflammatory Molecules as Biomarkers of Sleep Alterations: A Scoping Review

Vanessa Ibanez-del Valle et al.

Summary: There is a relationship between sleep quality and inflammatory markers in saliva, especially with IL-6 in both healthy subjects and various conditions associated with sleep disorders. Salivary inflammatory markers could be useful in chronobiology studies and as biomarkers for detecting sleep disorders and interventions. Further research is needed to determine the sensitivity of these markers in monitoring biological rhythms and sleep-related interventions.

DIAGNOSTICS (2021)

Article Biochemistry & Molecular Biology

Chronic Pain in the Elderly: Mechanisms and Distinctive Features

Andrea Tinnirello et al.

Summary: Research on pain in the elderly shows conflicting results, with some studies suggesting a modest decrease in pain sensitivity and others finding a reduced pain threshold. Elderly individuals are more prone to hyperalgesia, with pathologic changes in the central nervous system affecting pain processing.

BIOMOLECULES (2021)

Article Geriatrics & Gerontology

Comparing sleep quality in institutionalized and non-institutionalized elderly individuals

Raquel Martins da Silva et al.

AGING & MENTAL HEALTH (2020)

Review Clinical Neurology

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis

Wei Xu et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)

Article Nursing

Screen Time Exposure and Altered Sleep in Young Children With Epilepsy

Ying-Ying Lin et al.

JOURNAL OF NURSING SCHOLARSHIP (2020)

Article Clinical Neurology

Actigraphy-estimated sleep and 24-hour activity rhythms and the risk of dementia

Thom S. Lysen et al.

ALZHEIMERS & DEMENTIA (2020)

Article Psychology, Biological

Bidirectional relationships between sleep and biomarkers of stress and immunity in youth

Emily C. LaVoy et al.

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY (2020)

Article Geriatrics & Gerontology

Associations of sleep and depression with obesity and sarcopenia in middle-aged and older adults

Raquel Fabrega-Cuadros et al.

MATURITAS (2020)

Article Physiology

Seasonal differences in rhythmicity of salivary cortisol in healthy adults

Dominika Kanikowska et al.

JOURNAL OF APPLIED PHYSIOLOGY (2019)

Article Multidisciplinary Sciences

A survey on sleep assessment methods

Vanessa Ibanez et al.

Article Neurosciences

Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex

Michele Bellesi et al.

JOURNAL OF NEUROSCIENCE (2017)

Article Geriatrics & Gerontology

Measures of Sleep-Wake Patterns and Risk of Mild Cognitive Impairment or Dementia in Older Women

Susan J. Diem et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2016)

Review Pharmacology & Pharmacy

Review of Safety and Efficacy of Sleep Medicines in Older Adults

Jennifer L. Schroeck et al.

CLINICAL THERAPEUTICS (2016)

Article Medicine, General & Internal

Sleep Problems in the Elderly

Juan Carlos Rodriguez et al.

MEDICAL CLINICS OF NORTH AMERICA (2015)

Article Neurosciences

Neurobiological Consequences of Sleep Deprivation

Karim Alkadhi et al.

CURRENT NEUROPHARMACOLOGY (2013)

Review Psychology, Clinical

Sleep and Sleep Disorders in Older Adults

Kate Crowley

NEUROPSYCHOLOGY REVIEW (2011)

Article Geriatrics & Gerontology

Sleep Disturbances in Dementia What They Are and What To Do

Karen M. Rose et al.

JOURNAL OF GERONTOLOGICAL NURSING (2010)

Article Geriatrics & Gerontology

Sleep disturbances in nursing homes

A. B. Neikrug et al.

JOURNAL OF NUTRITION HEALTH & AGING (2010)

Article Geriatrics & Gerontology

Effect of individualized social activity on sleep in nursing home residents with dementia

KC Richards et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2005)

Article Rheumatology

Prevalence and impact of arthritis among nursing home residents

JE Abell et al.

ANNALS OF THE RHEUMATIC DISEASES (2004)