4.7 Review

Nanomaterials-based aptasensors: An efficient detection tool for heavy-metal and metalloid ions in environmental and biological samples

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Simultaneous detection of mercury (II), lead (II) and silver (I) based on fluorescently labelled aptamer probes and graphene oxide

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Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications

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Fullerene carbon dot catalytic amplification-aptamer assay platform for ultratrace As+3 utilizing SERS/RRS/Abs trifunctional Au nanoprobes

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A novel photoelectrochemical strategy for lead ion detection based on CdSe quantum dots co-sensitized ZnO-CdS nanostructure

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Sensitive and selective detection of Hg2 + in tap and canal water via self-enhanced ECL aptasensor based on NH2-Ru@SiO2-NGQDs

Libo Li et al.

Summary: In this study, a novel self-enhanced electrochemiluminescence (ECL) aptasensor was developed for sensitive and selective detection of Hg2+, utilizing a self-enhanced ECL composite with high and stable luminous efficiency. By employing a Hg2+ aptamer bridging NH2-Ru@SiO2-NGQDs and a glass carbon electrode, linearly enhanced ECL signals were obtained in the range of 5.0 x 10(-11) M to 1.0 x 10(-6) M, showing excellent selectivity, repeatability, and stability in 3 minutes. The aptasensor demonstrated satisfactory accuracy and practicability for Hg2+ analysis in tap and canal water, verified by ICP-MS.

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Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

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An Electrochemical Aptasensor for Pb2+ Detection Based on Metal-Organic-Framework-Derived Hybrid Carbon

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Article Engineering, Electrical & Electronic

Ratiometric fluorescent sensing of mercury (II) ion based on the Pt nanozyme-triggered fluorescence resonance energy transfer between Si quantum dots and 2,3-diaminophenazine

Wenjia Li et al.

Summary: The study developed a ratiometric fluorescence assay using nanozyme and fluorescence resonance energy transfer to efficiently detect mercury ion, which was validated for its reliability in Yangtze river water samples.

SENSORS AND ACTUATORS A-PHYSICAL (2021)

Article Chemistry, Analytical

Electrochemical biosensor for sensitive detection of Hg2+ baesd on clustered peonylike copper-based metal-organic frameworks and DNAzyme-driven DNA Walker dual amplification signal strategy

Hui Liu et al.

Summary: A sensitive electrochemical biosensor for Hg2+ detection was developed using a dual amplification signal strategy, showing linear detection range from 0.001-100 nM and a low detection limit of 0.52 pM. This biosensor was successfully applied in detecting Hg2+ in milk powder samples.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Chemistry, Analytical

Colorimetric and SERS dual-mode sensing of mercury (II) based on controllable etching of Au@Ag core/shell nanoparticles

Jinhua Wang et al.

Summary: A new strategy for colorimetric/SERS dual-mode determination of Hg2+ was proposed based on controllable etching Au@Ag NPs. The method showed excellent sensitivity and specificity, suitable for fast detecting of Hg2+.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Chemistry, Analytical

Ultra-sensitive electrochemical aptasensor based on zeolitic imidazolate framework-8 derived Ag/Au core-shell nanoparticles for mercury detection in water samples

N. Salandari-Jolge et al.

Summary: An electrochemical aptasensor based on Ag@Au/ZIF-8 modifier was developed successfully for mercury(II) detection, showing low detection limits and excellent repeatability.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Food Science & Technology

Establishment of an Indirect Competitive Enzyme-Linked Immunosorbent Method for the Detection of Heavy Metal Cadmium in Food Packaging Materials

Xianshu Fu et al.

Summary: Heavy metals in food packaging materials, especially cadmium, are a global environmental threat. This study proposed an ic-ELISA method based on a specific monoclonal antibody for rapid detection of Cd. The ic-ELISA showed high specificity and accuracy in diagnosing Cd in food packaging materials.
Article Engineering, Environmental

Near-infrared light-driven photoelectrochemical sensor for mercury (II) detection using bead-chain-like Ag@Ag2S nanocomposites

Lixiang Zhang et al.

Summary: An NIR light-driven PEC sensing platform was established for quantitative detection of Hg2+ using Ag@Ag2S nanocomposites. The sensor displayed enhanced PEC responses and selectivity, with a linear detection range of 0.0010 to 5.0 nM Hg2+ and a detection limit of about 0.50 pM, making it suitable for complex environmental monitoring.

CHEMICAL ENGINEERING JOURNAL (2021)

Article Chemistry, Applied

Sensing of mercury ions in Porphyra by Copper @ Gold nanoclusters based ratiometric fluorescent aptasensor

Yongqiang Shi et al.

Summary: A novel aptamer-modified Copper @ Gold nanoclusters based ratiometric fluorescent probe was developed for mercury ions determination in Porphyra, with a detection limit of 4.92 nM. Additionally, a homemade device for colorimetric determination of Hg2+ was designed, showing good portability and usefulness. The study suggests the considerable potential of these methods for evaluating Hg2+ levels in aquatic products.

FOOD CHEMISTRY (2021)

Review Engineering, Environmental

Nanomaterial-based fluorescent sensors for the detection of lead ions

Harpreet Singh et al.

Summary: This review focuses on the recent developments in fluorescent nanosensing technology for the detection of lead ions (Pb2+), highlighting the classification and evaluation of different types of nanomaterials, especially in terms of sensitivity.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Chemistry, Multidisciplinary

Recyclable Target Metal-Enhanced Fluorometric Naked Eye Aptasensor for the Detection of Pb2+ and Ag+ Ions Based on the Structural Change of CaSnO3@PDANS-Constrained GC-Rich ssDNA

Arunjegan Amalraj et al.

Summary: The novel aptasensor presented in this study utilizes DNA structural changes and fluorescence emission differences to detect Pb2+ and Ag+ ions with high sensitivity. The sensor demonstrates recyclability and utilizes the properties of GC-rich ssDNA and acridine orange for reliable and label-free detection.

ACS OMEGA (2021)

Article Chemistry, Analytical

Target-enhanced photoelectrochemical aptasensor for Cd(II) detection using graphite-like carbon nitride as sensitizer with high sensitivity

Yanyan Niu et al.

Summary: This study developed a PEC aptasensor for quantitative analysis of Cd(II) by changing the sensing interface structure to amplify the detection signal. The sensor showed high sensitivity with a detection limit of 1.1 x 10-11 mol/L and was successfully used for water sample detection.

MICROCHEMICAL JOURNAL (2021)

Review Chemistry, Analytical

Fluorescence and electrochemical assay for bimodal detection of lead ions based on Metal-Organic framework nanosheets

Guozhen Chen et al.

Summary: The study presents a bimodal strategy for signal-on, label-free lead ion detection in environmental samples using 2D-MOF nanosheets, which allows for both fluorescence and electrochemical detection with high sensitivity. The developed device is cost-effective, highly sensitive, and convenient to operate, showing promise as a reliable system for lead ion detection in environmental samples.

TALANTA (2021)

Review Chemistry, Analytical

Metal-organic frameworks conjugated with biomolecules as efficient platforms for development of biosensors

Paria Pashazadeh-Panahi et al.

Summary: Recent developments in metal-organic frameworks (MOFs) have attracted scientists' renewed interest for potential breakthroughs. These highly porous particles with large surface areas have diverse functionalities, making them powerful compounds in nanomedicine. Aside from their critical roles in adsorption and separation, they also play significant roles in biosensors, with ongoing efforts to modify and apply them in various platforms.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)

Review Biotechnology & Applied Microbiology

Advances in aptamer screening and aptasensors' detection of heavy metal ions

Wenfei Guo et al.

Summary: This paper reviews the seriousness of heavy metal pollution and the application of aptasensors in detecting heavy metal ions. It focuses on the methods for selecting aptamers with high specificity and high affinity, as well as the construction methods and research progress of aptamers based on sensors. Finally, the challenges and future opportunities of aptasensors in detecting heavy metal ions are discussed.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Article Toxicology

Effects of arsenic and heavy metals on metabolic pathways in cells of human origin: Similarities and differences

Kaniz Fatema et al.

Summary: Exposure to heavy metals has detrimental effects on cellular metabolic pathways, with the extent of impact depending on the type of metal and cell characteristics. Arsenic shows more widespread influences on cellular metabolic pathways, including those associated with diabetes.

TOXICOLOGY REPORTS (2021)

Review Chemistry, Physical

Nanomaterials based electrochemical nucleic acid biosensors for environmental monitoring: A review

Abu Hashem et al.

Summary: The ecosystem provides essential natural services to humans and other beings, environmental monitoring aims to assess changes in environmental quality, and biosensors offer an exciting approach to overcome limitations of traditional methods.

APPLIED SURFACE SCIENCE ADVANCES (2021)

Review Environmental Sciences

Electrochemical Biosensors for Detection of Pesticides and Heavy Metal Toxicants in Water: Recent Trends and Progress

Tony O. Hara et al.

Summary: This review highlights the progress made in the development of electrochemical biosensors for environmental toxicants (such as pesticides and heavy metals) over the past seven years. Emphasizing the importance of developing rapid, reliable, and sensitive analytical detection systems, the review discusses current challenges and potential directions for future research.

ACS ES&T WATER (2021)

Article Chemistry, Analytical

A novel photoelectrochemical sensor based on g-C3N4@CdS QDs for sensitive detection of Hg2+

Zhongping Li et al.

MICROCHEMICAL JOURNAL (2020)

Review Biotechnology & Applied Microbiology

Biological Applications and Toxicity Minimization of Semiconductor Quantum Dots

Samira Filali et al.

TRENDS IN BIOTECHNOLOGY (2020)

Article Biochemical Research Methods

Practical aptamer-based assay of heavy metal mercury ion in contaminated environmental samples: convenience and sensitivity

Yingying Qi et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)

Review Biophysics

Nanomaterial-based aptamer sensors for arsenic detection

Kang Mao et al.

BIOSENSORS & BIOELECTRONICS (2020)

Article Chemistry, Analytical

Electrochemical aptasensing of cadmium (II) on a carbon black-gold nano-platform

Colani T. Fakude et al.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies

Fadwa Odeh et al.

MOLECULES (2020)

Review Medicine, Legal

Arsenic exposure: A public health problem leading to several cancers

I. Palma-Lara et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2020)

Article Biochemical Research Methods

A low-cost paper-based aptasensor for simultaneous trace-level monitoring of mercury (II) and silver (I) ions

Zahra Khoshbin et al.

ANALYTICAL BIOCHEMISTRY (2020)

Review Environmental Sciences

Nickel: Human Health and Environmental Toxicology

Giuseppe Genchi et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Article Spectroscopy

A new and facile nanosilver SPR colored method for ultratrace arsenic based on aptamer regulation of Au-doped carbon dot catalytic amplification

Zhi-Hao Zhang et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

Review Biochemistry & Molecular Biology

A review: Recent advances in ultrasensitive and highly specific recognition aptasensors with various detection strategies

Shu-Rong Yan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Chemistry, Analytical

Electrochemical aptasensors based on the gold nanostructures

Masoud Negahdary

TALANTA (2020)

Article Electrochemistry

High Sensitive Electrochemical Luminescence Sensor for the Determination of Cd2+ in Spirulina

Zhizhong Wang et al.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2020)

Article Chemistry, Analytical

A novel label-free electrochemical aptasensor with one-step assembly process for rapid detection of lead (II) ions

Guojing Ran et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

Review Chemistry, Analytical

Recent advances in bismuth oxyhalide-based functional materials for photoelectrochemical sensing

Hao Wang et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2020)

Review Chemistry, Inorganic & Nuclear

State of the art recent progress in two dimensional MXenes based gas sensors and biosensors: A comprehensive review

Kalim Deshmukh et al.

COORDINATION CHEMISTRY REVIEWS (2020)

Review Chemistry, Analytical

Review of the distribution and detection methods of heavy metals in the environment

Mengting Jin et al.

ANALYTICAL METHODS (2020)

Review Chemistry, Analytical

Nanomaterial-enhanced chemiluminescence reactions and their applications

Ruyuan Wang et al.

ANALYST (2020)

Review Chemistry, Analytical

Nanomaterial-based fluorescent biosensors for monitoring environmental pollutants: A critical review

Maria Isabel Gaviria-Arroyave et al.

TALANTA OPEN (2020)

Review Chemistry, Analytical

Recent advances in nanomaterials-based electrochemical (bio)sensors for pesticides detection

Weiran Wang et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2020)

Review Chemistry, Analytical

Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media

Nerea De Acha et al.

SENSORS (2019)

Review Chemistry, Analytical

Application of nano-ELISA in food analysis: Recent advances and challenges

Long Wu et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2019)

Article Chemistry, Analytical

A simple paper-based aptasensor for ultrasensitive detection of lead (II) ion

Zahra Khoshbin et al.

ANALYTICA CHIMICA ACTA (2019)

Review Chemistry, Physical

A review on heavy metal pollution, toxicity and remedial measures: Current trends and future perspectives

Kilaru Harsha Vardhan et al.

JOURNAL OF MOLECULAR LIQUIDS (2019)

Review Biochemistry & Molecular Biology

G-Quadruplex-Forming Aptamers-Characteristics, Applications, and Perspectives

Carolina Roxo et al.

MOLECULES (2019)

Review Chemistry, Multidisciplinary

Wearable and Implantable Soft Bioelectronics Using Two-Dimensional Materials

Changsoon Choi et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Article Environmental Sciences

Plasmon resonance-enhanced internal reflection ellipsometry for the trace detection of mercuric ion

M. O. Caglayan

INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY (2018)

Review Biophysics

Electrochemical immunosensors - A powerful tool for analytical applications

Fabiana S. Felix et al.

BIOSENSORS & BIOELECTRONICS (2018)

Review Chemistry, Analytical

Current Progress in Aptasensors for Heavy Metal Ions Based on Photoelectrochemical Method: A Review

Bo Peng et al.

CURRENT ANALYTICAL CHEMISTRY (2018)

Article Electrochemistry

Enhanced electrochemiluminescent aptasensor for mercury based on CdTeSe@CdS QDs-DNA bioconjugates and enzymatic catalysis

Jian-Jun Shi et al.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2018)

Review Biotechnology & Applied Microbiology

Adverse effect of heavy metals (As, Pb, Hg, and Cr) on health and their bioremediation strategies: a review

Amit Pratush et al.

INTERNATIONAL MICROBIOLOGY (2018)

Article Chemistry, Analytical

cathodic signal-on photoelectrochemical sensor for Hg2+ detection based on ion-exchange with ZnS quantum dots

Yan Wang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

Review Chemistry, Analytical

Selective photoelectrochemical architectures for biosensing: Design, mechanism and responsibility

Wenwen Tu et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2018)

Article Chemistry, Analytical

Aptamer-based colorimetric determination of Pb2+ using a paper-based microfluidic platform

Neda Fakhri et al.

ANALYTICAL METHODS (2018)

Article Nanoscience & Nanotechnology

Aptamer-Based Electrochemical Biosensor for Mercury Ions Detection Using AuNPs-Modified Glass Carbon Electrode

Yuan Liu et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2018)

Review Biotechnology & Applied Microbiology

Aptamers as targeted therapeutics: current potential and challenges

Jiehua Zhou et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Article Chemistry, Multidisciplinary

Defining the copper binding aptamotif and aptamer integrated recovery platform (AIRP)

Simranjeet Singh Sekhon et al.

NANOSCALE (2017)

Review Chemistry, Analytical

Nanomaterial-based aptasensors and bioaffinity sensors for quantitative detection of 17β-estradiol

Alireza Nezami et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2017)

Review Electrochemistry

Electrochemical Biosensors in Point-of-Care Devices: Recent Advances and Future Trends

Everson T. S. G. da Silva et al.

CHEMELECTROCHEM (2017)

Review Materials Science, Multidisciplinary

A Review of Gold and Silver Nanoparticle-Based Colorimetric Sensing Assays

Myalowenkosi Sabela et al.

ADVANCED ENGINEERING MATERIALS (2017)

Review Biophysics

Nanomaterial-based electrochemical sensors for arsenic - A review

Sureshkumar Kempahanumakkagari et al.

BIOSENSORS & BIOELECTRONICS (2017)

Article Chemistry, Multidisciplinary

Thiourea functionalized CdSe/CdS quantum dots as a fluorescent sensor for mercury ion detection

Li-Li Xi et al.

CHINESE CHEMICAL LETTERS (2016)

Article Chemistry, Applied

Heavy metals in aromatic spices by inductively coupled plasma-mass spectrometry

Daniel Giuseppe Bua et al.

FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE (2016)

Article Environmental Sciences

An aptasensor for selective, sensitive and fast detection of lead(II) based on polyethyleneimine and gold nanoparticles

Seyed Mohammad Taghdisi et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2015)

Review Chemistry, Analytical

A review on detection of heavy metal ions in water - An electrochemical approach

Manju Bhargavi Gumpu et al.

SENSORS AND ACTUATORS B-CHEMICAL (2015)

Review Biochemical Research Methods

Graphene-based sensors for detection of heavy metals in water: a review

Jingbo Chang et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2014)

Article Biochemical Research Methods

Label-free fluorescent sensor for lead ion detection based on lead(II)-stabilized G-quadruplex formation

Shenshan Zhan et al.

ANALYTICAL BIOCHEMISTRY (2014)

Article Environmental Sciences

Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes

Seyed Mohammad Taghdisi et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2014)

Article Chemistry, Applied

A highly sensitive enzyme-linked immunosorbent assay for copper(II) determination in drinking water

Changrui Xing et al.

FOOD AND AGRICULTURAL IMMUNOLOGY (2014)

Review Biochemical Research Methods

SELEX-A (r)evolutionary method to generate high-affinity nucleic acid ligands

Regina Stoltenburg et al.

BIOMOLECULAR ENGINEERING (2007)

Article Biochemical Research Methods

Analysis of metal ions in crude oil by reversed-phase high performance liquid chromatography using short column

H. Salar Amolia et al.

JOURNAL OF CHROMATOGRAPHY A (2006)

Article Medicine, General & Internal

Hazards of heavy metal contamination

L Jarup

BRITISH MEDICAL BULLETIN (2003)

Review Multidisciplinary Sciences

Biochemistry - Adaptive recognition by nucleic acid aptamers

T Hermann et al.

SCIENCE (2000)