期刊
ENVIRONMENTAL RESEARCH
卷 238, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.envres.2023.117170
关键词
Aptasensor; Nanomaterials; Heavy metals; Environmental monitoring; Biological samples
Diverse aptasensors have been developed through the combination of aptamers with nanomaterials for the timely and efficient detection of metals in environmental and biological matrices. These sensors have multiple advantages such as heightened sensitivity, facile production, uncomplicated operation, exceptional specificity, enhanced stability, low immunogenicity, and cost-effectiveness.
In light of potential risks of heavy metal exposure, diverse aptasensors have been developed through the combination of aptamers with nanomaterials for the timely and efficient detection of metals in environmental and biological matrices. Aptamer-based sensors can benefit from multiple merits such as heightened sensitivity, facile production, uncomplicated operation, exceptional specificity, enhanced stability, low immunogenicity, and costeffectiveness. This review highlights the detection capabilities of nanomaterial-based aptasensors for heavymetal and metalloid ions based on their performance in terms of the basic quality assurance parameters (e.g., limit of detection, linear dynamic range, and response time). Out of covered studies, dendrimer/CdTe@CdS QDsbased ECL aptasensor was found as the most sensitive option with an LOD of 2.0 aM (atto-molar: 10-18 M) detection for Hg2+. The existing challenges in the nanomaterial-based aptasensors and their scientific solutions are also discussed.
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