Evidence of serial connection between the plasma volume and two interstitial fluid compartments

Review Critical Care Medicine

Hypovolemia with peripheral edema: What is wrong?

Randal O. Dull et al.

Summary: Fluid balance plays a crucial role in maintaining normal physiology, but can be disrupted by diseases and medications. Inflammatory conditions and anesthesia can lead to impaired fluid return and accumulation in the tissues, causing a range of circulatory dysregulation. Experimental studies have identified the involvement of inflammatory mediators and nitric oxide in this process, highlighting potential targets for therapeutic interventions.

CRITICAL CARE (2023)

添加到收藏夹

Article Critical Care Medicine

Fast versus slow infusion of 20% albumin: a randomized controlled cross-over trial in volunteers

Markus Zdolsek et al.

Summary: This study investigated the difference in plasma volume expansion when administering 20% albumin rapidly compared to slowly. The results showed that the rapid infusion led to a larger plasma volume expansion in the first two hours, but both infusion rates had similar effects afterwards. The intravascular persistence of albumin was longer with rapid infusion, and urine output was three times larger than the infused volume. Atrial natriuretic peptide accelerated albumin leakage and urine flow.

INTENSIVE CARE MEDICINE EXPERIMENTAL (2022)

添加到收藏夹

Review Physiology

Function of Renal Nerves in Kidney Physiology and Pathophysiology

John W. Osborn et al.

Summary: Renal sympathetic and sensory nerves play crucial roles in regulating kidney function, with overactivity linked to hypertension and other cardiometabolic diseases. Clinical trials of catheter-based renal nerve ablation for treating hypertension have shown promising results, highlighting the importance of further research into how renal nerves function and can be targeted for novel therapies.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 83 (2021)

添加到收藏夹

Article Cell Biology

Role of Renal Sympathetic Nerve Activity in Volatile Anesthesia's Effect on Renal Excretory Function

Micael Taavo et al.

Summary: The volatile anesthetic sevoflurane induces renal sodium and water retention by increasing renal sympathetic nerve activity, leading to decreased renal blood flow. Renal denervation can normalize renal excretory function and improve renal blood flow during sevoflurane anesthesia.

FUNCTION (2021)

添加到收藏夹

Review Anesthesiology