相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The centrosome is an actin-organizing centre
Francesca Farina et al.
NATURE CELL BIOLOGY (2016)
HNF4 alpha is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer
Hae Ryung Chang et al.
GUT (2016)
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Roni Nowarski et al.
CELL (2015)
Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis
Jessica I. Grill et al.
DIGESTIVE DISEASES AND SCIENCES (2015)
Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells
Linh M. Vuong et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab
E. Zulato et al.
BRITISH JOURNAL OF CANCER (2014)
The One Hour Yeast Proteome
Alexander S. Hebert et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Chromatin Profiling Reveals Regulatory Network Shifts and a Protective Role for Hepatocyte Nuclear Factor 4α during Colitis
Sanjay Chahar et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Proteogenomic characterization of human colon and rectal cancer
Bing Zhang et al.
NATURE (2014)
Hepatocyte-specific deletion of hepatocyte nuclear factor-4 alpha in adult mice results in increased hepatocyte proliferation
Chad Walesky et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)
Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents
Chad Walesky et al.
HEPATOLOGY (2013)
Regulation of the tumor suppressor homeogene Cdx2 by HNF4α in intestinal cancer
T. Saandi et al.
ONCOGENE (2013)
Endogenous Purification Reveals GREB1 as a Key Estrogen Receptor Regulatory Factor
Hisham Mohammed et al.
CELL REPORTS (2013)
Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis
Georgia Drakakaki et al.
CELL RESEARCH (2012)
Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks
Martina Perse et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)
Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
Ahmed Elbediwy et al.
JOURNAL OF CELL BIOLOGY (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
Landscape of transcription in human cells
Sarah Djebali et al.
NATURE (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
FXR Controls the Tumor Suppressor NDRG2 and FXR Agonists Reduce Liver Tumor Growth and Metastasis in an Orthotopic Mouse Xenograft Model
Ulrich Deuschle et al.
PLOS ONE (2012)
Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer
Karthikeyani Chellappa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis
Maria Hatziapostolou et al.
CELL (2011)
Proteomic Analysis of Native Hepatocyte Nuclear Factor-4α (HNF4α) Isoforms, Phosphorylation Status, and Interactive Cofactors
Kenji Daigo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Temporal genomewide expression profiling of DSS colitis reveals novel inflammatory and angiogenesis genes similar to ulcerative colitis
Kai Fang et al.
PHYSIOLOGICAL GENOMICS (2011)
Hepatocyte Nuclear Factor-4α Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species
Mathieu Darsigny et al.
CANCER RESEARCH (2010)
Developmental and Tissue-Specific Regulation of Hepatocyte Nuclear Factor 4-α (HNF4-α) Isoforms in Rodents
SAMENA DEAN et al.
GENE EXPRESSION (2010)
Making the Liver What It Is: The Many Targets of the Transcriptional Regulator HNF4α
Klaus H. Kaestner
HEPATOLOGY (2010)
Integrated Approach for the Identification of Human Hepatocyte Nuclear Factor 4α Target Genes Using Protein Binding Microarrays
Eugene Bolotin et al.
HEPATOLOGY (2010)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke et al.
NATURE GENETICS (2010)
A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation
Marlon R. Schneider et al.
PLOS ONE (2010)
Activation of PPARγ by rosiglitazone attenuates intestinal Cl- secretion
Poonam J. Bajwa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Loss of Ca2+-mediated ion transport during colitis correlates with reduced ion transport responses to a Ca2+-activated K+ channel opener
Christina L. Hirota et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Novel P2 promoter-derived HNF4α isoforms with different N-terminus generated by alternate exon insertion
Jianmin Huang et al.
EXPERIMENTAL CELL RESEARCH (2009)
Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases
Kathryn E. Tifft et al.
JOURNAL OF CELL SCIENCE (2009)
Hepatocyte Nuclear Factor 4α, a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium
Anne-Laure Cattin et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
Jeffrey C. Barrett et al.
NATURE GENETICS (2009)
Proliferation defects and genome instability in cells lacking Cul4A
D. Kopanja et al.
ONCOGENE (2009)
Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice
Mathieu Darsigny et al.
PLOS ONE (2009)
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
Katharina Brandl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Physiology and Function of the Tight Junction
James M. Anderson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Megaintestine in claudin-15-deficient mice
Atsushi Tamura et al.
GASTROENTEROLOGY (2008)
Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease
Sung-Hoon Ahn et al.
INFLAMMATORY BOWEL DISEASES (2008)
Alternative Promoters Influence Alternative Splicing at the Genomic Level
Dedong Xin et al.
PLOS ONE (2008)
Epithelial restitution and wound healing in inflammatory bowel disease
Andreas Sturm et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
Expansion of adult β-cell mass in response to increased metabolic demand is dependent on HNF-4α
Rana K. Gupta et al.
GENES & DEVELOPMENT (2007)
Downregulated P1 promoter-driven hepatocyte nuclear factor-4α expression in human colorectal carcinoma is a new prognostic factor against liver metastasis
Tomoko Oshima et al.
PATHOLOGY INTERNATIONAL (2007)
An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
Clemens Neufert et al.
NATURE PROTOCOLS (2007)
Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate mode of colitis
Laila D. McVay et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
Hiroyuki Motoshima et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Resistin-like molecule β regulates innate colonic function:: Barrier integrity and inflammation susceptibility
Simon P. Hogan et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
Michele A. Battle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4α in the pathogenesis of human cancer
T Tanaka et al.
JOURNAL OF PATHOLOGY (2006)
Hepatocyte nuclear factor 4α is essential for embryonic development of the mouse colon
WD Garrison et al.
GASTROENTEROLOGY (2006)
In vivo role of the HNF4α AF-1 activation domain revealed by exon swapping
N Briançon et al.
EMBO JOURNAL (2006)
Hepatocyte nuclear factor-4α is essential for glucosestimulated insulin secretion by pancreatic β-cells
A Miura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young
Sian Ellard et al.
HUMAN MUTATION (2006)
Regulation of RELM/FIZZ isoform expression by Cdx2 in response to innate and adaptive immune stimulation in the intestine
ML Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2
A Reiter et al.
CANCER RESEARCH (2005)
The peroxisome proliferator-activated receptor γ ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency
C Lytle et al.
INFLAMMATORY BOWEL DISEASES (2005)
Control of pancreas and liver gene expression by HNF transcription factors
DT Odom et al.
SCIENCE (2004)
RELMβ/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract
D Artis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Protein kinase CβII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo
Y Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
AMP-activated protein kinase regulates HNF4α transcriptional activity by inhibiting dimer formation and decreasing protein stability
YH Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hepatocyte nuclear factor 4α Isoforms originated from the P1 promoter are expressed in human pancreatic β-cells and exhibit stronger transcriptional potentials than P2 promoter-driven isoforms
J Eeckhoute et al.
ENDOCRINOLOGY (2003)
Bacterial colonization leads to the colonic secretion of RELM beta/FIZZ2, a novel goblet cell-specific protein
WM He et al.
GASTROENTEROLOGY (2003)
Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
GP Hayhurst et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Chloride secretion by the intestinal epithelium: Molecular basis and regulatory aspects
KE Barrett et al.
ANNUAL REVIEW OF PHYSIOLOGY (2000)
分享论文
