4.8 Article

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders

Yang Yang et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2015)

Review Biochemistry & Molecular Biology

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

Kevin W. Tipping et al.

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Article Biochemistry & Molecular Biology

Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

Lisa M. Ryno et al.

ACS CHEMICAL BIOLOGY (2014)

Editorial Material Multidisciplinary Sciences

Chemical con artists foil drug discovery

Jonathan Baell et al.

NATURE (2014)

Article Multidisciplinary Sciences

Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain

Christina B. Cooley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Cell Biology

Proteostasis impairment in protein-misfolding and -aggregation diseases

Mark S. Hipp et al.

TRENDS IN CELL BIOLOGY (2014)

Review Biochemistry & Molecular Biology

The molecular and cellular pathology of α1-antitrypsin deficiency

Bibek Gooptu et al.

TRENDS IN MOLECULAR MEDICINE (2014)

Review Biochemistry & Molecular Biology

Systemic Amyloidoses

Luis M. Blancas-Mejia et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)

Article Chemistry, Medicinal

Protein Homeostasis as a Therapeutic Target for Diseases of Protein Conformation

Barbara Calamini et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

Romain Volmer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Small-molecule proteostasis regulators for protein conformational diseases

Barbara Calamini et al.

NATURE CHEMICAL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

Likun Wang et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Cell Biology

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Claudio Hetz

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Ophthalmology

Selective Activation of ATF6 and PERK Endoplasmic Reticulum Stress Signaling Pathways Prevent Mutant Rhodopsin Accumulation

Wei-Chieh Chiang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)

Review Multidisciplinary Sciences

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

Melanie H. Smith et al.

SCIENCE (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Article Cell Biology

Cellular Strategies of Protein Quality Control

Bryan Chen et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

Evan T. Powers et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2009)

Review Biotechnology & Applied Microbiology

Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds

Yan Feng et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Review Biochemistry & Molecular Biology

Protein misfolding and disease: from the test tube to the organism

Leila M. Luheshi et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2008)

Article Biotechnology & Applied Microbiology

Gene expression-based screening for inhibitors of PDGFR signaling

Alena A. Antipova et al.

GENOME BIOLOGY (2008)

Article Biochemistry & Molecular Biology

A molecular chaperone inducer protects neurons from ER stress

T. Kudo et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Chemistry, Medicinal

Aminopyrrolidineamide inhibitors of site-1 protease

Bruce A. Hay et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Biochemistry & Molecular Biology

Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress

Satomi Nadanaka et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Cytoplasmic IRE1α-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress

Sung Hoon Back et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biotechnology & Applied Microbiology

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter et al.

GENOME BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

PD Lu et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

A transgenic mouse model for monitoring endoplasmic reticulum stress

T Iwawaki et al.

NATURE MEDICINE (2004)

Article Multidisciplinary Sciences

Bypassing a kinase activity with an ATP-competitive drug

FR Papa et al.

SCIENCE (2003)

Article Biochemistry & Molecular Biology

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

J Ye et al.

MOLECULAR CELL (2000)