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Fei Huang et al.
NUCLEIC ACIDS RESEARCH (2016)
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
Katherine Sullivan et al.
PLOS ONE (2016)
Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers
Gurushankar Chandramouly et al.
CHEMISTRY & BIOLOGY (2015)
Regulation of Recombination and Genomic Maintenance
Wolf-Dietrich Heyer
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
An Overview of the Molecular Mechanisms of Recombinational DNA Repair
Stephen C. Kowalczykowski
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Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins
Rohit Prakash et al.
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Sally R. Ellingson et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
PALB2: The hub of a network of tumor suppressors involved in DNA damage responses
Jung-Young Park et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2014)
Replication protein A: Single-stranded DNA's first responder Dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair
Ran Chen et al.
BIOESSAYS (2014)
Breast Cancer Proteins PALB2 and BRCA2 Stimulate Polymerase h in Recombination-Associated DNA Synthesis at Blocked Replication Forks
Remi Buisson et al.
CELL REPORTS (2014)
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile
Kimberly Cramer-Morales et al.
BLOOD (2013)
Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway
Jarin Chun et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
B. H. Lok et al.
ONCOGENE (2013)
Repair of Strand Breaks by Homologous Recombination
Maria Jasin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Genomic Instability in Cancer
Tarek Abbas et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function
Ivana Murfuni et al.
PLOS GENETICS (2013)
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
Katharina Schlacher et al.
CANCER CELL (2012)
Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic Advancement
Benjamin H. Lok et al.
CLINICAL CANCER RESEARCH (2012)
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
Hyungjin Kim et al.
GENES & DEVELOPMENT (2012)
Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking
Michael M. Mysinger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Small-molecule inhibitors of dimeric transcription factors: Antagonism of protein-protein and protein-DNA interactions
Jeremy L. Yap et al.
MEDCHEMCOMM (2012)
Downregulation of Mus81 as a novel prognostic biomarker for patients with colorectal carcinoma
Fan Wu et al.
CANCER SCIENCE (2011)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Katharina Schlacher et al.
CELL (2011)
Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination
Rasmus Vejrup-Hansen et al.
DNA REPAIR (2011)
Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding
Masayoshi Honda et al.
EMBO JOURNAL (2011)
Hybrid Steered Molecular Dynamics-Docking: An Efficient Solution to the Problem of Ranking Inhibitor Affinities Against a Flexible Drug Target
Katie L. Whalen et al.
MOLECULAR INFORMATICS (2011)
Rad52 inactivation is synthetically lethal with BRCA2 deficiency
Zhihui Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Towards Accurate Free Energy Calculations in Ligand Protein-Binding Studies
Thomas Steinbrecher et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Collaboration and competition between DNA double-strand break repair pathways
Elizabeth M. Kass et al.
FEBS LETTERS (2010)
Replication protein A: directing traffic at the intersection of replication and repair
Greg G. Oakley et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2010)
Software News and Update AutoDock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization, and Multithreading
Oleg Trott et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
Purified human BRCA2 stimulates RAD51-mediated recombination
Ryan B. Jensen et al.
NATURE (2010)
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
Mary Ellen Moynahan et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
Jie Liu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
Tina Thorslund et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
Eloiese Dray et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes
Jill M. Grimme et al.
NUCLEIC ACIDS RESEARCH (2010)
The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51
Aura Carreira et al.
CELL (2009)
Rad52
Uffe H. Mortensen et al.
CURRENT BIOLOGY (2009)
Homologous recombination in DNA repair and DNA damage tolerance
Xuan Li et al.
CELL RESEARCH (2008)
Identification of a second DNA binding site in the human Rad52 protein
Wataru Kagawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair
Michael J. Mcllwraith et al.
MOLECULAR CELL (2008)
Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes
Eli Rothenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Use of amino acid composition to predict ligand-binding sites
Shinji Soga et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)
Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter space
Marwen Naim et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)
Benchmarking sets for molecular docking
Niu Huang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
A critical assessment of docking programs and scoring functions
Gregory L. Warren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
HJ Yang et al.
NATURE (2005)
Identification of residues important for DNA binding in the full-length human Rad52 protein
JA Lloyd et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Making optimal use of empirical energy functions: Force-field parameterization in crystal space
E Krieger et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51
CL Doe et al.
NUCLEIC ACIDS RESEARCH (2004)
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells
C Couédel et al.
GENES & DEVELOPMENT (2004)
Correlation of biochemical properties with the oligomeric state of human Rad52 protein
JA Lloyd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structure of the single-strand annealing domain of human RAD52 protein
MR Singleton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form
W Kagawa et al.
MOLECULAR CELL (2002)
Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line
RJ Yáñez et al.
NUCLEIC ACIDS RESEARCH (2002)
WaterLOGSY as a method for primary NMR screening: Practical aspects and range of applicability
C Dalvit et al.
JOURNAL OF BIOMOLECULAR NMR (2001)
Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing
E Van Dyck et al.
EMBO REPORTS (2001)
Homologous pairing promoted by the human Rad52 protein
W Kagawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining
F Xia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Free energy calculations on dimer stability of the HIV protease using molecular dynamics and a continuum solvent model
W Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water
C Dalvit et al.
JOURNAL OF BIOMOLECULAR NMR (2000)
The human Rad52 protein exists as a heptameric ring
AZ Stasiak et al.
CURRENT BIOLOGY (2000)
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