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Russell E. Ericksen et al.
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Valérie Gouazé-Andersson et al.
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Ayuna Hattori et al.
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Simon Raffel et al.
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Adonia E. Papathanassiu et al.
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Lidia Santos Silva et al.
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Qianghu Wang et al.
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I-Wei Chang et al.
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Narges K. Tafreshi et al.
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Jianjian Zhao et al.
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Jared R. Mayers et al.
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Hong-Gang Wang et al.
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Uday B. Maachani et al.
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Justin V. Joseph et al.
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Zhi-Qiang Wang et al.
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Sung-Hak Kim et al.
STEM CELL REPORTS (2015)
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Elitsa A. Ananieva et al.
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Peifeng Hou et al.
PLOS ONE (2014)
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Jared R. Mayers et al.
NATURE MEDICINE (2013)
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
Martje Toenjes et al.
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Isaac Marin-Valencia et al.
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Wei Xu et al.
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Nu Zhang et al.
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Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma
Francesca Pistollato et al.
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Electrochemical behaviour of dimethyl-2-oxoglutarate on glassy carbon electrode
Afzal Shah et al.
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Branched-chain Amino Acid Metabolon INTERACTION OF GLUTAMATE DEHYDROGENASE WITH THE MITOCHONDRIAL BRANCHED-CHAIN AMINOTRANSFERASE (BCATm)
Mohammad Mainul Islam et al.
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Single-vector inducible lentiviral RNAi system for oncology target validation
Dmitri Wiederschain et al.
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Hypoxia-inducible factor-1α blocks differentiation of malignant gliomas
Huimin Lu et al.
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Li-Min Xia et al.
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ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Yifang Hu et al.
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The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism
MS Ullah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
MG Liu et al.
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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
HS Phillips et al.
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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
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Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin
M Goto et al.
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AJL Cooper et al.
ANALYTICAL BIOCHEMISTRY (2002)
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
A Jögi et al.
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