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The CRISPR Revolution: Unraveling the mysteries of Life's genetic code

期刊

GENE
卷 892, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.gene.2023.147870

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CRISPR-Cas; Genome editing; Gene therapy; Cancer therapy

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A biotechnological revolution is triggered by the versatility, accuracy, and efficiency of CRISPR-Cas systems. Diagnosing nucleic acid biomarkers using CRISPR is a highly sensitive method. It can detect a wide range of infectious and non-infectious diseases, mutations, and CRISPR deletions associated with genetic disorders. Additionally, this technology has applications in protein and micromolecule testing. However, despite its many contributions to biomedical science, CRISPR technology has negative impacts on the health of living organisms, environmental conditions, and population structures.
A biotechnological revolution is triggered by CRISPR-Cas systems' variety, measured quality, and proficiency. Identifying nucleic acid biomarkers, one of the methods that use CRISPR for diagnosis, is an extremely sensitive diagnostic method.A broad range of infectious and noninfecting diseases, mutations, and CRISPR deletions associated with genetic disorders have been detected using diagnostics. Furthermore, this technology is used to test proteins and micromolecules. We focus on how Cas proteins can be used to detect diseases in genes, agriculture, and cancer therapy. Furthermore, CRISPR technology has many negative impacts on the health of living organisms, environmental and population structures in spite of its numerous contributions to biomedical science. Therefore, an investigation into the impact of genome editing on nontargeted species is important for these reasons. CRISPR in the future is briefly discussed towards the end of this review.

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