4.5 Article

Incidence of opioid misuse by cigarette smoking status in the United States

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Summary: The review provides an update on the rising trend of illicit fentanyls, overdose risks, and treatment options, particularly focusing on the increasing use of synthetic opioids like fentanyl and its analogs in the US. Methamphetamine and cocaine-driven stimulant-related overdoses are also on the rise nationwide, contributing to the 'fourth wave' of high mortality involving these substances. The use of illicit fentanyls remains a major contributor to overdose deaths, and the increase in stimulant-related deaths seems to be connected to the ongoing opioid epidemic.

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