4.7 Article

4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Loss of miR-34 in Drosophila dysregulates protein translation and protein turnover in the aging brain

Ananth R. Srinivasan et al.

Summary: This study investigates the role of miR-34 in age-related phenotypes in the brain, finding that miR-34 regulates translation, protein aggregation, and autophagy. Additionally, the study suggests that miR-34 may target Lst8 and other genes involved in maintaining proteostasis and brain health.

AGING CELL (2022)

Article Endocrinology & Metabolism

miRNA-22 deletion limits white adipose expansion and activates brown fat to attenuate high-fat diet-induced fat mass accumulation

Vanessa M. Lima et al.

Summary: miR-22 plays a role in white, beige, and brown adipocyte differentiation. Deletion of miR-22 reduces white adipocyte differentiation, increases BAT activity, and enhances resistance in HFD-fed mice.

METABOLISM-CLINICAL AND EXPERIMENTAL (2021)

Article Cardiac & Cardiovascular Systems

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

Theresa A. McDonagh et al.

EUROPEAN HEART JOURNAL (2021)

Review Biotechnology & Applied Microbiology

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

Henry Jay Forman et al.

Summary: Oxidative stress plays a role in various diseases, and understanding the mechanisms behind antioxidants and how to enhance antioxidant defences may lead to greater pharmacological success.

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Biochemistry & Molecular Biology

Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling

Yohan Santin et al.

CELL DEATH AND DIFFERENTIATION (2020)

Article Cardiac & Cardiovascular Systems

4HNE Impairs Myocardial Bioenergetics in Congenital Heart Disease-Induced Right Ventricular Failure

HyunTae V. Hwang et al.

CIRCULATION (2020)

Article Multidisciplinary Sciences

Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression

Andrea Livia Rocha et al.

SCIENCE ADVANCES (2020)

Article Pathology

DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma

Maria Apellaniz-Ruiz et al.

JOURNAL OF PATHOLOGY CLINICAL RESEARCH (2020)

Article Multidisciplinary Sciences

A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats

Julio C. B. Ferreira et al.

NATURE COMMUNICATIONS (2019)

Review Biochemistry & Molecular Biology

Targeting mitochondrial dysfunction and oxidative stress in heart failure: Challenges and opportunities

Ligia Akemi Kiyuna et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Article Biology

Why antioxidant therapies have failed in clinical trials

Adrian M. Davies et al.

JOURNAL OF THEORETICAL BIOLOGY (2018)

Article Cardiac & Cardiovascular Systems

Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: Benefits of Alda-1

Katia M. S. Gomes et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

Review Oncology

MicroRNA biogenesis pathways in cancer

Shuibin Lin et al.

NATURE REVIEWS CANCER (2015)

Review Physiology

TARGETING ALDEHYDE DEHYDROGENASE 2: NEW THERAPEUTIC OPPORTUNITIES

Che-Hong Chen et al.

PHYSIOLOGICAL REVIEWS (2014)

Article Biochemical Research Methods

Fluorescence-Based High-Throughput Screening of Dicer Cleavage Activity

Katerina Podolska et al.

JOURNAL OF BIOMOLECULAR SCREENING (2014)

Article Cell Biology

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

Sameer Kalghatgi et al.

SCIENCE TRANSLATIONAL MEDICINE (2013)

Article Multidisciplinary Sciences

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

Sonia Melo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

ALDH2 Activator Inhibits Increased Myocardial Infarction Injury by Nitroglycerin Tolerance

Lihan Sun et al.

SCIENCE TRANSLATIONAL MEDICINE (2011)

Article Biochemistry & Molecular Biology

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

Samantha Perez-Miller et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Conditional Dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling

Paula A. da Costa Martins et al.

CIRCULATION (2008)

Article Biotechnology & Applied Microbiology

A small molecule enhances RNA interference and promotes microRNA processing

Ge Shan et al.

NATURE BIOTECHNOLOGY (2008)

Review Genetics & Heredity

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Witold Filipowicz et al.

NATURE REVIEWS GENETICS (2008)

Article Multidisciplinary Sciences

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

Jian-Fu Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

Che-Hong Chen et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Structural determinants of RNA recognition and cleavage by Dicer

Ian J. MacRae et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

Structural basis for double-stranded RNA processing by dicer

IJ MacRae et al.

SCIENCE (2006)

Article Chemistry, Medicinal

Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal

JA Doorn et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2006)

Article Biochemistry & Molecular Biology

Role of oxidative stress in paraquat-induced dopaminergic cell degeneration

AL McCormack et al.

JOURNAL OF NEUROCHEMISTRY (2005)

Article Multidisciplinary Sciences

Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells:: A possible mechanism for lipid peroxidation-induced carcinogenesis

ZH Feng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Role for a bidentate ribonuclease in the initiation step of RNA interference

E Bernstein et al.

NATURE (2001)