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Review
Biology
Xiaojiang Xu et al.
Summary: This paper reviews three-dimensional models for human thermoregulation. It introduces the development of thermoregulatory models and key principles for mathematical description. Different representations of 3D human bodies are discussed, and recent models have used medical image datasets to develop geometrically correct human models. Finite element method is commonly used for solving governing equations and obtaining numerical solutions. These realistic geometry models provide high anatomical realism and can predict whole-body thermo-regulatory responses at a high resolution.
JOURNAL OF THERMAL BIOLOGY
(2023)
Article
Biology
Michael P. Castellani et al.
Summary: This study developed a female finite element thermoregulatory model (FETM) by constructing an anatomically correct female body model from medical image datasets. The model considers heat balance within the body and heat exchange at the skin surface, as well as the regulation mechanisms of vasodilation, vasoconstriction, sweating, and shivering. The model was validated with measured physiological data and predicted core temperature and mean skin temperatures accurately.
JOURNAL OF THERMAL BIOLOGY
(2023)
Article
Construction & Building Technology
Yinping Ou et al.
Summary: This study systematically examined the core temperature responses of elderly individuals during prolonged heatwaves and developed a modified thermoregulatory model to predict survival time. The results showed that dehydration resulting from intense heat stress could lead to fatal classic heatstroke, and increased air temperature and humidity could shorten the survival duration. The developed model can accurately predict the core temperature responses of healthy elderly individuals exposed to extreme heat and aid in the selection of efficient heatstroke prevention measures suited to the elderly.
BUILDING AND ENVIRONMENT
(2023)
Article
Biology
Jie Yang et al.
Summary: A numerical hand-glove/mitten model was developed to simulate human hand physiological responses in various cold environments. The model reasonably predicted cold-induced vasodilation responses at 0°C temperature, and provided fundamental knowledge for cold stress prediction and protective glove development.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Biology
Michael P. Castellani et al.
Summary: This paper outlines the development of a finite element human thermoregulatory model using an anatomically and geometrically correct human body model. The model simulates thermal responses through a passive and active system, providing insight into human thermoregulatory responses to non-uniform and transient environments. Comprehensive validation shows predictions are accurate and acceptable, with comparisons of predicted temperatures at 29 sites with measured values in comfort, hot, and cold conditions.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Biophysics
Xiaojiang Xu et al.
Summary: The paper introduces a Cold Weather Ensemble Decision Aid (CoWEDA) that guides users on cold weather injury prevention, mission planning, and clothing selection by incorporating science from physiology, meteorology, clothing, and computer modeling. CoWEDA predicts the risk of frostbite and hypothermia, ensuring selected clothing ensembles are appropriate for expected weather conditions and activities. Additionally, it represents a significant enhancement of required clothing insulation and wind chill index-based guidance for cold weather safety and survival.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2021)
Article
Construction & Building Technology
Mengying Zhang et al.
Summary: A 3D multi-segment hand-specific thermoregulation model was developed to predict skin temperature, considering cold-induced vasodilation in fingers. The model, based on realistic anatomical and physiological information, divided the hand into 17 segments and included heat transfer mechanisms such as metabolism and blood perfusion. The model showed good agreement with experimental data and can enhance working efficiency, safety, health, and wellbeing in cold environments.
BUILDING AND ENVIRONMENT
(2021)
Article
Biology
Alvin Pengshi Tan et al.
Summary: Physiologically based thermoregulatory models, such as the SCENARIO model, are useful for predicting heat strain during high-intensity physical tasks under hot and humid conditions. The optimized SCENARIO model showed good accuracy in predicting body core temperature, with bias, RMSD, RMSD-Mean, and SDP values indicating strong performance both during in-sample analysis and external validation. Future work to further validate the model with new data and enhance it for more accurate simulations of other heat strain markers is recommended.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Biology
Xiaojiang Xu et al.
JOURNAL OF THERMAL BIOLOGY
(2018)
Article
Public, Environmental & Occupational Health
Florence Riera et al.
AVIATION SPACE AND ENVIRONMENTAL MEDICINE
(2014)
Article
Physiology
Xiaojiang Xu et al.
COMPREHENSIVE PHYSIOLOGY
(2014)
Article
Biology
Xiaojiang Xu et al.
JOURNAL OF THERMAL BIOLOGY
(2011)
Article
Physiology
John W. Castellani et al.
JOURNAL OF APPLIED PHYSIOLOGY
(2007)
Article
Physiology
Xiaojiang Xu et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2007)
Article
Biology
XJ Xu et al.
COMPUTERS IN BIOLOGY AND MEDICINE
(2005)
Article
Physiology
P Tikuisis
JOURNAL OF APPLIED PHYSIOLOGY
(2003)
Article
Biophysics
WG Van Dorn
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2000)