☆ 4.6 Article

Etamsylate loaded oxidized Konjac glucomannan-ε-polylysine injectable hydrogels for rapid hemostasis and wound healing

JOURNAL OF MATERIALS CHEMISTRY B (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Applied

Facile fabrication of self-healing, injectable and antimicrobial cationic guar gum hydrogel dressings driven by hydrogen bonds

Yan Wang et al.

Summary: A novel hydrogen-bonded polysaccharide hydrogel consisting of cationic guar gum and CuCl2 was developed, which exhibited self-healing, injectable, and self-adapting properties. The hydrogel showed good mechanical strength, biocompatibility, antibacterial ability, and complete degradation in vivo. This study provides a simple and straightforward strategy for preparing self-healing polysaccharide hydrogels based on hydrogen bonding, expanding their applications in biomedicine and tissue regeneration.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Article Chemistry, Applied

High-strength, antibacterial, antioxidant, hemostatic, and biocompatible chitin/PEGDE-tannic acid hydrogels for wound healing

Hankun Cao et al.

Summary: Novel multifunctional chitin/PEGDE-tannic acid (CPT) hydrogels were successfully fabricated, showing stable three-dimensional porous structure, excellent biocompatibility, improved mechanical properties, and various functions including antibacterial, antioxidant, hemostatic activities. These CPT hydrogels could promote wound healing by regulating inflammatory responses, promoting collagen deposition, and blood vessel formation. This study provides a useful strategy to fabricate multifunctional CPT hydrogels and they hold promise for wound healing applications.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Article Chemistry, Applied

Interpenetrating network expansion sponge based on chitosan and plasma for ultrafast hemostasis of arterial bleeding wounds

Yuting Shi et al.

Summary: Preventing arterial hemorrhage is crucial, but current hemostatic materials are not effective in extreme conditions. Therefore, we developed an expansion sponge based on chitosan and plasma, which provides a simpler and more efficient method for treating high-pressure arterial bleeding wounds.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Article Chemistry, Applied

A triple-network carboxymethyl chitosan-based hydrogel for hemostasis of incompressible bleeding on wet wound surfaces

Zheng Chen et al.

Summary: This study prepared a novel CMCS/ODex/gamma-PGA hydrogel for the treatment of diffuse and incompressible wound bleeding. The hydrogel showed good hemostatic effect and maintained adhesion in wet environments. This study provides a new method for designing wet-surface adhesives for efficient hemostasis.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Article Chemistry, Applied

Silk composite interfacial layer eliminates rebleeding with chitosan-based hemostats

Sushma Indrakumar et al.

Summary: Researchers have developed a bilayered foam that can quickly clot blood, reduce bleeding, and be easily removed without causing rebleeding.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Article Engineering, Biomedical

Multi-crosslinked hydrogels with strong wet adhesion, self-healing, antibacterial property, reactive oxygen species scavenging activity, and on-demand removability for seawater-immersed wound healing

Yicheng Lv et al.

Summary: A multifunctional hydrogel has been developed for the treatment of seawater-immersed wounds. The hydrogel demonstrates high wet adhesion, eliminates Marine bacteria, inhibits biofilm formation, and has various desirable properties such as injectability, self-healing, reactive oxygen species scavenging activity, photothermal effect, seawater isolation, on-demand removal, and hemostatic properties. In vivo tests show that the hydrogel exhibits antibacterial, anti-inflammatory, and antioxidant properties, and accelerates the healing process of seawater-immersed infected wounds.

ACTA BIOMATERIALIA (2023)

添加到收藏夹

Article Chemistry, Applied

A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care

Abhishek Kumar et al.

Summary: We developed a sodium alginate-based Ca2+ and Zn2+ composite hydrogel (SA-CZ) and evaluated its hemostatic potential. SA-CZ hydrogel exhibited significant in-vitro efficacy, reducing coagulation time and improving blood coagulation index without causing hemolysis. In a hemorrhage model in mice, SA-CZ significantly decreased bleeding time and mean blood loss. It also promoted cellular migration and wound closure in-vitro and in-vivo. Importantly, SA-CZ demonstrated good biocompatibility and non-thromboembolic nature, making it a safe and effective aid for bleeding wounds.

CARBOHYDRATE POLYMERS (2023)

添加到收藏夹

Review Polymer Science

Polysaccharide-Based Multifunctional Hydrogel Bio-Adhesives for Wound Healing: A Review

Jiahao Yang et al.

Summary: This review discusses the design criteria and functionalities of hydrogel bio-adhesives for wound healing and comprehensively explores recent advances in polysaccharide-based multifunctional hydrogel bio-adhesives. Polysaccharides such as chitosan, hyaluronic acid, alginate, cellulose, dextran, konjac glucomannan, chondroitin sulfate, and others are discussed. The current challenges and future research directions of polysaccharide-based hydrogel bio-adhesives for wound healing are proposed.

GELS (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

pH/Glucose Dual Responsive Metformin Release Hydrogel Dressings with Adhesion and Self-Healing via Dual-Dynamic Bonding for Athletic Diabetic Foot Wound Healing

Yongping Liang et al.

Summary: A dual-responsive hydrogel dressing was constructed for the treatment of type II diabetic foot ulcers and shown to promote wound healing in a rat model. The addition of metformin and graphene oxide further enhanced wound repair.

ACS NANO (2022)

添加到收藏夹

Review Polymer Science

Konjac glucomannan: A review of structure, physicochemical properties, and wound dressing applications

Ning Zhou et al.

Summary: Recently, natural bio-based materials like Konjac glucomannan (KGM) have shown great potential in wound dressings due to their water retention, biocompatibility, and therapeutic properties. By combining KGM with other polymers, the mechanical properties can be improved to promote wound healing.

JOURNAL OF APPLIED POLYMER SCIENCE (2022)

添加到收藏夹

Article Chemistry, Applied

Shear-thinning and self-healing chitosan-graphene oxide hydrogel for hemostasis and wound healing

Wenjun Feng et al.

Summary: This article reports on the fabrication of an injectable and self-healing hydrogel through one-pot heating of chitosan and graphene oxide mixture solution. The resulting hydrogel exhibits good adhesiveness, hemostatic, and wound healing capabilities, making it a promising candidate for wound dressings.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹

Article Nanoscience & Nanotechnology

Bioinspired Injectable Self-Healing Hydrogel Sealant with Fault-Tolerant and Repeated Thermo-Responsive Adhesion for Sutureless Post-Wound-Closure and Wound Healing

Yuqing Liang et al.

Summary: This article introduces a multifunctional hydrogel adhesive prepared by a bioinspired dynamic bond cross-linking method, which can be used for seamless wound closure and wound healing. The hydrogel has sufficient mechanical and adhesive strength, as well as injectability and self-healing capacity, which can effectively close wounds and repeatedly close reopened wounds. In addition, it also has good biocompatibility, antibacterial activity, and hemostatic effect.

NANO-MICRO LETTERS (2022)

添加到收藏夹

Article Materials Science, Biomaterials

Ascidian-inspired aciduric hydrogels with high stretchability and adhesiveness promote gastric hemostasis and wound healing

Wenliang Xue et al.

Summary: The aciduric bionic hydrogel adhesives, inspired by the high adhesiveness of the ascidian secretory protein, show great potential in treating gastric hemorrhages and promoting wound healing, due to their enhanced wet tissue adhesion, higher stretchability, and aciduric stability.

BIOMATERIALS SCIENCE (2022)

添加到收藏夹

Article Biophysics

Design and synthesis of a new topical agent for halting blood loss rapidly: A multimodal chitosan-gelatin xerogel composite loaded with silica nanoparticles and calcium

Gokul Patil et al.

Summary: An efficient multimodal topical hemostat was developed by ionically crosslinking chitosan and gelatin to fabricate a robust xerogel with high porosity. The composite exhibited improved blood clotting in vitro, good biocompatibility, and achieved faster hemostasis compared to commercial products in vivo.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹

Article Materials Science, Biomaterials

A γ-PGA/KGM-based injectable hydrogel as immunoactive and antibacterial wound dressing for skin wound repair

Ling Zhu et al.

Summary: This study aimed to prepare an injectable hydrogel (P-OK) by combining konjac glucomannan and gamma-polyglutamic acid, which showed fast gelation time, good water-retention rate, low cytotoxicity, immunomodulating, and antibacterial capabilities. The P-OK hydrogel has the potential to shorten the healing period in wound repair dressing.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Injectable Self-Healing Adhesive pH-Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing

Jiahui He et al.

Summary: A series of injectable pH-responsive self-healing adhesive hydrogels have been developed for treating gastric bleeding and wound healing after endoscopic treatment. These hydrogels show great potential as endoscopic sprayable bioadhesive materials, with good hemostatic properties and enhanced wound healing effects in animal models.

NANO-MICRO LETTERS (2021)

添加到收藏夹

Review Polymer Science

Advances in Injectable and Self-healing Polysaccharide Hydrogel Based on the Schiff Base Reaction

Chunxiang Mo et al.

Summary: Injectable hydrogel has great potential in disease treatment and tissue engineering, but damage often occurs during injection and use, leading to rapid degradation and material leakage. Self-healing hydrogels, especially those based on the Schiff base reaction, can automatically repair structural defects and restore function, making them ideal for biological applications such as drug delivery and cell therapy.

MACROMOLECULAR RAPID COMMUNICATIONS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Novel Diabetic Foot Wound Dressing Based on Multifunctional Hydrogels with Extensive Temperature-Tolerant, Durable, Adhesive, and Intrinsic Antibacterial Properties

Hou Liu et al.

Summary: This study developed a temperature-tolerant antibacterial hydrogel dressing with excellent properties, effectively promoting the healing of diabetic foot ulcers (DFUs).

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biodegradable hydrogel with thermo-response and hemostatic effect for photothermal enhanced anti-infective therapy

Changyu Cao et al.

Summary: The platelet-inspired degradable antibacterial hydrogel Gel/PP-TA-Ag shows promising hemostatic and antibacterial effects, with potential application in infected wound healing.

NANO TODAY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Haemostatic materials for wound healing applications

Baolin Guo et al.

Summary: Wounds are a common health issue, and the cost of wound care and healing has been increasing. Hemostasis is the first step in wound healing, and various forms and components of hemostatic materials have been developed. Future directions in the development of hemostatic materials focus on addressing challenges in wound healing.

NATURE REVIEWS CHEMISTRY (2021)

添加到收藏夹

Article Materials Science, Multidisciplinary

Synthesis and characterization of an injectable ε-polylysine/carboxymethyl chitosan hydrogel used in medical application

Yucan Wang et al.

MATERIALS CHEMISTRY AND PHYSICS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Controlled release of silver ions from AgNPs using a hydrogel based on konjac glucomannan and chitosan for infected wounds

Yungang Jiang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Chemistry, Physical

Composite Hemostatic Nonwoven Textiles Based on Hyaluronic Acid, Cellulose, and Etamsylate

Pavel Suchy et al.

MATERIALS (2020)

添加到收藏夹

Article Chemistry, Applied

Fabrication and characterization of matrine-loaded konjac glucomannan/fish gelatin composite hydrogel as antimicrobial wound dressing

Liping Zhou et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Materials Science, Biomaterials

A novel injectable starch-based tissue adhesive for hemostasis

Ruihua Cui et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Article Chemistry, Applied

Preparation and characterization of konjac glucomannan-based bionanocomposite film for active food packaging

Chunhua Wu et al.

FOOD HYDROCOLLOIDS (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Health-promoting effects of konjac glucomannan and its practical applications: A critical review

Ramya Devi Devaraj et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Article Biophysics

An investigation of konjac glucomannan-keratin hydrogel scaffold loaded with Avena sativa extracts for diabetic wound healing

Praveen Krishna Veerasubramanian et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Haemostatic agent etamsylate in vitro and in vivo antagonizes anticoagulant activity of heparin

M. Yolanda Cobo-Nunez et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

添加到收藏夹

Review Chemistry, Applied

Modifications of konjac glucomannan for diverse applications

Fan Zhu

FOOD CHEMISTRY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Carboxymethyl konjac glucomannan - crosslinked chitosan sponges for wound dressing

Yu Xie et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

添加到收藏夹

Article Chemistry, Applied

An injectable self-healing hydrogel with adhesive and antibacterial properties effectively promotes wound healing

Honglei Chen et al.

CARBOHYDRATE POLYMERS (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

A Review on Konjac Glucomannan Gels: Microstructure and Application

Dan Yang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

添加到收藏夹

Article Chemistry, Applied

pH-Sensitive drug delivery system based on hydrophobic modified konjac glucomannan

Jinling Luan et al.

CARBOHYDRATE POLYMERS (2017)

添加到收藏夹

Article Chemistry, Applied

Rapidly in situ forming chitosan/ε-polylysine hydrogels for adhesive sealants and hemostatic materials

Wei Nie et al.

CARBOHYDRATE POLYMERS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Dual Functions of Highly Potent Graphene Derivative-Poly-L-Lysine Composites To Inhibit Bacteria and Support Human Cells

Surajit Some et al.

ACS NANO (2012)

添加到收藏夹

Article Chemistry, Applied

Electrospinning and characterization of konjac glucomannan/chitosan nanofibrous scaffolds favoring the growth of bone mesenchymal stem cells

Huarong Nie et al.

CARBOHYDRATE POLYMERS (2011)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.