4.5 Article

Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Demonstration of the Feasibility of Predicting the Flow of Pharmaceutically Relevant Powders from Particle and Bulk Physical Properties

Herve Barjat et al.

Summary: The study focused on understanding and predicting the flow of bulk pharmaceutical materials for pharmaceutical manufacturing by continuous direct compression (CDC). By analyzing particle properties, powder measurements and using statistical modeling, researchers were able to build predictive models for flow. Results showed that static image analysis could predict flow in shear cells related to performance in a CDC system, with little powder needed for analysis, while surface area and surface energy techniques did not significantly contribute to the precision of the model.

JOURNAL OF PHARMACEUTICAL INNOVATION (2021)

Article Pharmacology & Pharmacy

The relevance of granule fragmentation on reduced tabletability of granules from ductile or brittle materials produced by roll compaction/dry granulation

Anne Linnet Skelbaek-Pedersen et al.

Summary: The study found that granule hardening and granule size enlargement are the two main reasons for the decrease in tabletability during roll compaction. In this study, increasing roll compaction force and granule size led to granule hardening, reducing the susceptibility of granules to fragmentation during tableting. Additionally, the presence of magnesium stearate further decreased tabletability by reducing fragmentation tendency of larger granules.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Pharmacology & Pharmacy

Elastic recovery in roll compaction simulation

Hannah L. Keizer et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Pharmacology & Pharmacy

Investigation on the effect of roller compaction on paracetamol

Justin Yong Soon Tay et al.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2020)

Article Pharmacology & Pharmacy

Prediction of tablet weight variability in continuous manufacturing

Sonia M. Razavi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Chemistry, Medicinal

Impact of roll compaction design, process parameters, and material deformation behaviour on ribbon relative density

Kitti Csordas et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)

Article Pharmacology & Pharmacy

Gaining insight into tablet capping tendency from compaction simulation

Shubhajit Paul et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

Article Pharmacology & Pharmacy

Development of a continuous direct compression platform for low-dose drug products

B. Van Snick et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

Article Pharmacology & Pharmacy

Mini review: Mechanisms to the loss of tabletability by dry granulation

Changquan Calvin Sun et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)

Article Pharmacology & Pharmacy

Applying surface energy derived cohesive-adhesive balance model in predicting the mixing, flow and compaction behaviour of interactive mixtures

Sharad Mangal et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)

Review Pharmacology & Pharmacy

A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage forms

Michael Leane et al.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2015)

Article Engineering, Chemical

Determination of the tensile strength of elongated tablets

Kendal G. Pitt et al.

POWDER TECHNOLOGY (2013)

Article Pharmacology & Pharmacy

Roller compaction process development and scale up using Johanson model calibrated with instrumented roll data

Vishwas V. Nesarikar et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)

Article Engineering, Chemical

Decoding Powder Tabletability: Roles of Particle Adhesion and Plasticity

Changquan Calvin Sun

JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY (2011)

Article Pharmacology & Pharmacy

Roll compaction as a dry granulation method for paracetamol

I. Jeon et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2011)

Article Pharmacology & Pharmacy

Degree of compression as a potential process control tool of tablet tensile strength

Josefina Nordstrom et al.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2011)

Article Chemistry, Multidisciplinary

Effect of Surface Energy on Powder Compactibility

Frauke Fichtner et al.

PHARMACEUTICAL RESEARCH (2008)

Article Chemistry, Medicinal

Determination of the surface energy distributions of different processed lactose

Frank Thielmann et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2007)

Article Pharmacology & Pharmacy

Roll compaction/dry granulation: Effect of raw material particle size on granule and tablet properties

Michael G. Herting et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Chemistry, Medicinal

Improving the prediction of exceptionally poor tableting performance: An investigation into Hiestand's special case

MP Mullarney et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2004)

Article Pharmacology & Pharmacy

The effect of shape and porosity on the compression behaviour and tablet forming ability of granular materials formed from microcrystalline cellulose

B Johansson et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2001)

Article Chemistry, Multidisciplinary

Fracture property studies of paracetamol single crystals using microindentation techniques

KVR Prasad et al.

PHARMACEUTICAL RESEARCH (2001)

Article Pharmacology & Pharmacy

The changes in surface energetics with relative humidity of carbamazepine and paracetamol as measured by inverse gas chromatography

MR Sunkersett et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2001)

Article Engineering, Chemical

Acid-base surface free energies of solids and the definition of scales in the Good-van Oss-Chaudhury theory

C Della Volpe et al.

JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY (2000)