期刊
BIOMATERIALS SCIENCE
卷 4, 期 4, 页码 555-574出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5bm00481k
关键词
-
资金
- University of Regensburg
- DFG [DI 1748/3-1]
- Spanish Ministry of Education [CTQ2014-52588-R, RTC-2014-2038-1]
- Generalitat de Catalunya [2014/SGR/624]
- Instituto de Salud Carlos III [CB06_01_0019]
- Spanish Ministry of Education, Culture and Sports
- Deutsche Forschungsgemeinschaft (DFG)
Hydrogels are hydrophilic three-dimensional networks with demonstrated potential for medical and pharmaceutical applications. Specifically, biopolymer-based hydrogels offer certain advantages over synthetic polymers in terms of biocompatibility and biodegradability. Because of their inherent properties, hydrogels are able to efficiently encapsulate and liberate in a controlled release manner, different hydrophobic and hydrophilic therapeutic molecules, including nucleic acids, proteins and antibodies. Several strategies have been reported in the literature to minimize the potential burst release of encapsulated drugs, thus preventing their local accumulation and consequent toxic responses. Within this context, liposomes embedded in hydrogels have emerged as an attractive strategy to reduce this undesirable effect. This tutorial review covers a selection of the most promising cationic, neutral and anionic biopolymer-based hydrogels containing liposomes, niosomes or vesicles for drug delivery or tissue engineering applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据