期刊
BIOMATERIALS SCIENCE
卷 4, 期 6, 页码 953-957出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6bm00186f
关键词
-
资金
- JSPS KAKENHI Grant [13F03353]
Temperature-and electric field-responsive polymer-conjugated polystyrene beads, termed smart beads, are designed to isolate cancer cells. In smart beads, the reversible on-off antigen-antibody reaction and dielectrophoresis force on an electrode are accomplished to realize on-off remote manipulation of smart beads and cancer cells. Both the zeta-potential and the hydrodynamic diameter of the smart beads are sensitive to temperature, allowing on-off reversible capture and release of cancer cells. Cancer cell-captured smart beads are then localized on electrodes by applying an electrical signal.
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