4.5 Review

Engineering β-sheet peptide assemblies for biomedical applications

期刊

BIOMATERIALS SCIENCE
卷 4, 期 3, 页码 365-374

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c5bm00472a

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  1. Natural Science Foundation of China (NSFC) Project [81541086, 51403042, 31370781]

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Hydrogels have been widely studied in various biomedical applications, such as tissue engineering, cell culture, immunotherapy and vaccines, and drug delivery. Peptide-based nanofibers represent a promising new strategy for current drug delivery approaches and cell carriers for tissue engineering. This review focuses on the recent advances in the use of self-assembling engineered beta-sheet peptide assemblies for biomedical applications. The applications of peptide nanofibers in biomedical fields, such as drug delivery, tissue engineering, immunotherapy, and vaccines, are highlighted. The current challenges and future perspectives for self-assembling peptide nanofibers in biomedical applications are discussed.

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