相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Richard J. Mead et al.
NATURE REVIEWS DRUG DISCOVERY (2023)
Tofersen: First Approval
Hannah A. Blair
DRUGS (2023)
Pathogenicity classification of SOD1 variants of uncertain significance by in vitro aggregation propensity
Lu-Xi Chen et al.
NEUROBIOLOGY OF AGING (2023)
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
Timothy M. Miller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2022)
SOD1, more than just an antioxidant
Elis Cristina Araujo Eleutherio et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2021)
Therapeutic news in ALS
P. Corcia et al.
REVUE NEUROLOGIQUE (2021)
Masitinib as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomized clinical trial
Jesus S. Mora et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2020)
Tamoxifen for amyotrophic lateral sclerosis A randomized double-blind clinical trial
Po-Chih Chen et al.
MEDICINE (2020)
Amyotrophic lateral sclerosis: a clinical review
P. Masrori et al.
EUROPEAN JOURNAL OF NEUROLOGY (2020)
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
Timothy Miller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Oral levosimendan in amyotrophic lateral sclerosis: a phase II multicentre, randomised, double-blind, placebo-controlled trial
Ammar Al-Chalabi et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)
Antisense oligonucleotides: the next frontier for treatment of neurological disorders
Carlo Rinaldi et al.
NATURE REVIEWS NEUROLOGY (2018)
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models
Alex McCampbell et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Amyotrophic lateral sclerosis
Michael A. van Es et al.
LANCET (2017)
Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
Koji Abe et al.
LANCET NEUROLOGY (2017)
Decoding ALS: from genes to mechanism
J. Paul Taylor et al.
NATURE (2016)
Rho Kinase Inhibition Modulates Microglia Activation and Improves Survival in a Model of Amyotrophic Lateral Sclerosis
Lars Toenges et al.
GLIA (2014)
State of play in amyotrophic lateral sclerosis genetics
Alan E. Renton et al.
NATURE NEUROSCIENCE (2014)
The Calcium Sensitizer Levosimendan Improves Human Diaphragm Function
Jonne Doorduin et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
Han-Xiang Deng et al.
NATURE (2011)
Prevention of Motor Neuron Degeneration by Novel Iron Chelators in SOD1(G93A) Transgenic Mice of Amyotrophic Lateral Sclerosis
Qian Wang et al.
NEURODEGENERATIVE DISEASES (2011)
Safety, Tolerability, and Cerebrospinal Fluid Penetration of Ursodeoxycholic Acid in Patients With Amyotrophic Lateral Sclerosis
Gareth J. Parry et al.
CLINICAL NEUROPHARMACOLOGY (2010)
The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 Å Resolution: Insights into Heparin and Collagen Binding
Svetlana V. Antonyuk et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
Smita Saxena et al.
NATURE NEUROSCIENCE (2009)
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Hideki Nishitoh et al.
GENES & DEVELOPMENT (2008)
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
Koji Yamanaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cognitive impairment in amyotrophic lateral sclerosis
Julie Phukan et al.
LANCET NEUROLOGY (2007)
Antisense oligonucleotide therapy for neurodegenerative disease
Richard A. Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Amyotrophic lateral sclerosis associated with mutations in the CuZn superoxide dismutase gene
Peter M. Andersen
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2006)
Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model
GS Ralph et al.
NATURE MEDICINE (2005)
Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis
E Kabashi et al.
JOURNAL OF NEUROCHEMISTRY (2004)
The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
C Lomen-Hoerth et al.
NEUROLOGY (2002)
Medical progress: Amyotrophic lateral sclerosis.
LP Rowland et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
分享论文
