Rapid fabrication of magnetic covalent organic frameworks for the effective extraction and determination of sulfonamides in shrimp samples

In this work, a magnetic covalent organic frameworks (COFs) named Fe3O4@TpBD was rapidly synthesized by an ultrasonic method, which reduced the synthesis time to 1.5 h. Fe3O4@TpBD was used as a magnetic solid-phase extraction (MSPE) adsorbent for the extraction and enrichment of five common sulfonamides, and there were different enrichment multiples ranging from 5 to 30. The limits of detection (LODs) of this method were 0.31-0.73 ng mL(-1), the limits of quantitation were 1.03-2.44 ng mL(-1), and the intraday and interday relative standard deviations (RSDs) were <9.72 % and <6.89 %, respectively. Moreover, the MSPE method was successfully applied for the determination of sulfonamides in shrimp samples.

Automated summary

In this study, a magnetic covalent organic framework (COFs) named Fe3O4@TpBD was rapidly synthesized using an ultrasonic method, which greatly reduced the synthesis time. Fe3O4@TpBD was used as a magnetic solid-phase extraction (MSPE) adsorbent for the extraction and enrichment of sulfonamides with low limits of detection and good stability. The MSPE method was successfully applied to the determination of sulfonamides in shrimp samples.