期刊
FOOD AND AGRICULTURAL IMMUNOLOGY
卷 34, 期 1, 页码 -出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09540105.2023.2265688
关键词
Agarwood leaves; Aquilaria crassna; post-harvest; yeast extract; anti-inflammatory activity; anti-diabetic activity
This study demonstrates the post-harvest process of agarwood leaves using yeast extract as an elicitor and evaluates its anti-inflammatory and anti-diabetic effects. The results show that yeast extract treatment significantly increases the content of active compounds in agarwood leaves and exhibits higher anti-inflammatory and anti-diabetic effects.
Agarwood (Aquilaria crassna) leaves are commonly used as an herbal tea for health supplements. The present study aims to develop the post-harvest process of agarwood leaves using yeast extract (YE) as an elicitor and evaluate its anti-inflammatory and anti-diabetic effects. The results showed that 1% of YE elicitation for 120 min significantly increased genkwanin 5-O-beta-primevoside (1.8-fold), mangiferin (1.3-fold), and total benzophenones (1.2-fold) contents over the control group. The phenylalanine ammonia-lyase (PAL) activity increased in maximal at 30 min after YE treatment. The agarwood leaf elicitation with 1% YE for 120 min showed a higher anti-inflammation effect by down-regulation of iNOS, IL-6, and COX-2 in LPS-stimulated RAW264.7 cells and an anti-diabetic effect by enhanced AMPK-alpha 1, AMPK-alpha 2, and GLUT4 in L6 cells over the non-treatment. Our results suggest that YE could be a biotic elicitor to enhance the phytochemical contents and increase the benefit of agarwood leaves as a health supplement. [GRAPHICS] .
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