☆ 4.6 Article

Charting Disease Trajectories from Isolated REM Sleep Behavior Disorder to Parkinson's Disease

MOVEMENT DISORDERS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Multidisciplinary Sciences

Forecasting individual progression trajectories in Alzheimer's disease

Etienne Maheux et al.

Summary: This study developed a statistical model, AD Course Map, for predicting the progression of Alzheimer's disease (AD) based on current medical and radiological data. The model was tested on a large dataset of over 96,000 cases and showed high accuracy in predicting clinical endpoints. By enriching the population with predicted progressors, the required sample size for trials could be reduced by 38% to 50%.

NATURE COMMUNICATIONS (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Forecasting individual progression trajectories in Huntington disease enables more powered clinical trials

Igor Koval et al.

Summary: This study utilizes disease course mapping to forecast biomarker progression for individual carriers of the pathological CAG repeat expansions responsible for Huntington disease, in order to select participants at risk for progression and compute the power of trials for such an enriched population, ultimately reducing sample sizes and ensuring a more homogeneous group of participants.

SCIENTIFIC REPORTS (2022)

添加到收藏夹

Article Clinical Neurology

Parkinson Disease Propagation Using MRI Biomarkers and Partial Least Squares Path Modeling

Nadya Pyatigorskaya et al.

Summary: Using multimodal MRI and PLS-PM, this study found that PD patients with RBD followed the Braak brainstem-to-cortex model of neurodegeneration, while those without RBD followed the cortex-to-brainstem model.

NEUROLOGY (2021)

添加到收藏夹

Article Clinical Neurology

Sequence of clinical and neurodegeneration events in Parkinson's disease progression

Neil P. Oxtoby et al.

Summary: This study estimated the sequence of Parkinson's disease progression in patients at elevated risk for dementia, beginning with classic prodromal features, offering a route to earlier and more precise detection and characterizing variability in the sequence.

BRAIN (2021)

添加到收藏夹

Review Clinical Neurology

Prodromal Parkinson disease subtypes - key to understanding heterogeneity

Daniela Berg et al.

Summary: Parkinson's disease begins its pathological processes and neurodegeneration long before clinical diagnosis, allowing for identification of individuals likely to develop the disease through risk and prodromal markers. Heterogeneity in clinical and prodromal PD suggests that subtypes exist, differentiated by clinical manifestations, pathomechanisms, and progression patterns. Understanding this variability is crucial for early and accurate diagnosis, as well as for targeting neuroprotective interventions effectively.

NATURE REVIEWS NEUROLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

AD Course Map charts Alzheimer's disease progression

Igor Koval et al.

Summary: This paper introduces a spatiotemporal atlas called AD Course Map for Alzheimer's disease progression, highlighting strong genetic determinants for the progression and predicting patients' cognitive decline with better accuracy than other benchmarked methods. The map also offers new tools for exploring the progression of Alzheimer's disease and personalizing patients care through simulations of virtual patient cohorts.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Clinical Neurology

Longitudinal Changes in Parkinson's Disease Symptoms with and Without Rapid Eye Movement Sleep Behavior Disorder: The Oxford Discovery Cohort Study

Yaping Liu et al.

Summary: Patients with PD comorbid with rapid eye movement sleep behavior disorder (RBD) exhibit more severe motor and cognitive symptoms, progress faster, and are associated with an increased risk for mild cognitive impairment, freezing of gait, and frequent falling. This suggests the presence of a more aggressive subtype of PD that can be identified early and has significant clinical implications.

MOVEMENT DISORDERS (2021)

添加到收藏夹

Article Medical Informatics

Discovery of Parkinson's disease states and disease progression modelling: a longitudinal data study using machine learning

Kristen A. Severson et al.

Summary: The study developed a statistical progression model of early Parkinson's disease that accounts for intra-individual and inter-individual variability and medication effects. The predictive model discovered non-sequential, overlapping disease progression trajectories, supporting the use of non-deterministic disease progression models, and suggesting static subtype assignment might be ineffective at capturing the full spectrum of Parkinson's disease progression.

LANCET DIGITAL HEALTH (2021)

添加到收藏夹

Article Clinical Neurology

Natural history of motor symptoms in Parkinson's disease and the long-duration response to levodopa

Roberto Cilia et al.

BRAIN (2020)

添加到收藏夹

Article Clinical Neurology

Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study

Jacob Horsager et al.

BRAIN (2020)

添加到收藏夹

Article Clinical Neurology

Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson's disease

Emma Biondetti et al.

BRAIN (2020)

添加到收藏夹

Article Neurosciences

The clinical heterogeneity of Parkinson's disease and its therapeutic implications

Julia C. Greenland et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2019)

添加到收藏夹

Article Clinical Neurology

Clinical progression in Parkinson's disease with features of REM sleep behavior disorder: A population-based longitudinal study

Aline Duarte Folle et al.

PARKINSONISM & RELATED DISORDERS (2019)

添加到收藏夹

Article Clinical Neurology

Evolution of prodromal Parkinson's disease and dementia with Lewy bodies: a prospective study

Seyed-Mohammad Fereshtehnejad et al.

BRAIN (2019)

添加到收藏夹

Article Clinical Neurology

Prognosis and Neuropathologic Correlation of Clinical Subtypes of Parkinson Disease

Eduardo De Pablo-Fernandez et al.

JAMA NEUROLOGY (2019)

添加到收藏夹

Proceedings Paper Computer Science, Information Systems

Bayesian Longitudinal Modeling of Early Stage Parkinson's Disease Using DaTscan Images

Yuan Zhou et al.

INFORMATION PROCESSING IN MEDICAL IMAGING, IPMI 2019 (2019)

添加到收藏夹

Proceedings Paper Engineering, Biomedical

LEARNING DISEASE PROGRESSION MODELS WITH LONGITUDINAL DATA AND MISSING VALUES

Raphael Couronne et al.

2019 IEEE 16TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2019) (2019)

添加到收藏夹

Article Clinical Neurology

In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study

Karoline Knudsen et al.

LANCET NEUROLOGY (2018)

添加到收藏夹

Article Clinical Neurology

Longitudinal analysis of impulse control disorders in Parkinson disease

Jean-Christophe Corvol et al.

NEUROLOGY (2018)

添加到收藏夹

Article Clinical Neurology

Reproducibility of data-driven Parkinson's disease subtypes for clinical research

Tiago A. Mestre et al.

PARKINSONISM & RELATED DISORDERS (2018)

添加到收藏夹

Article Clinical Neurology

Developing and validating Parkinson's disease subtypes and their motor and cognitive progression

Michael Lawton et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2018)

添加到收藏夹

Article Clinical Neurology

Estimating the Evolution of Disease in the Parkinson's Progression Markers Initiative

Samuel Iddi et al.

NEURODEGENERATIVE DISEASES (2018)

添加到收藏夹

Article Clinical Neurology

Disease progression in Parkinson subtypes: the PPMI dataset

Darko Aleksovski et al.

NEUROLOGICAL SCIENCES (2018)

添加到收藏夹

Article Clinical Neurology

Clinical criteria for subtyping Parkinson's disease: biomarkers and longitudinal progression

Seyed-Mohammad Fereshtehnejad et al.

BRAIN (2017)

添加到收藏夹

Article Clinical Neurology

Defining imaging biomarker cut points for brain aging and Alzheimer's disease

Clifford R. Jack et al.

ALZHEIMERS & DEMENTIA (2017)

添加到收藏夹

Review Clinical Neurology

A review of disease progression models of Parkinson's disease and applications in clinical trials

Charles S. Venuto et al.

MOVEMENT DISORDERS (2016)

添加到收藏夹

Article Clinical Neurology

Nonmotor features of Parkinson's disease subtypes

Connie Marras et al.

MOVEMENT DISORDERS (2016)

添加到收藏夹

Review Clinical Neurology

MDS research criteria for prodromal Parkinson's disease

Daniela Berg et al.

MOVEMENT DISORDERS (2015)

添加到收藏夹

Article Clinical Neurology

Parkinson's disease severity levels and MDS-Unified Parkinson's Disease Rating Scale

Pablo Martinez-Martin et al.

PARKINSONISM & RELATED DISORDERS (2015)

添加到收藏夹

Article Clinical Neurology

New Clinical Subtypes of Parkinson Disease and Their Longitudinal Progression A Prospective Cohort Comparison With Other Phenotypes

Seyed-Mohammad Fereshtehnejad et al.

JAMA NEUROLOGY (2015)

添加到收藏夹

Article Clinical Neurology

REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease

Michal Rolinski et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)

添加到收藏夹

Article Clinical Neurology

How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder

R. B. Postuma et al.

BRAIN (2012)

添加到收藏夹

Article Clinical Neurology

Rapid eye movement sleep behavior disorder and subtypes of Parkinson's disease

Silvia Rios Romenets et al.

MOVEMENT DISORDERS (2012)

添加到收藏夹

Article Clinical Neurology

Age-Specific Progression of Nigrostriatal Dysfunction in Parkinson's Disease

Raul de la Fuente-Fernandez et al.

ANNALS OF NEUROLOGY (2011)

添加到收藏夹

Article Clinical Neurology

The progression of pathology in Parkinson's disease

Glenda Margaret Halliday et al.

YEAR IN NEUROLOGY 2 (2010)

添加到收藏夹

Article Clinical Neurology

Hallucinations and sleep disorders in PD Ten-year prospective longitudinal study

Christopher G. Goetz et al.

NEUROLOGY (2010)

添加到收藏夹

Article Clinical Neurology

Markers of neurodegeneration in idiopathic rapid eye movement sleep behaviour disorder and Parkinson's disease

R. B. Postuma et al.

BRAIN (2009)

添加到收藏夹

Article Clinical Neurology

Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study

R. Nandhagopal et al.

BRAIN (2009)

添加到收藏夹

Article Clinical Neurology

Parkinson's Disease with and without REM Sleep Behaviour Disorder: Are There Any Clinical Differences?

Asako Yoritaka et al.

EUROPEAN NEUROLOGY (2009)

添加到收藏夹

Article Clinical Neurology

The progression of pathology in longitudinally followed patients with Parkinson's disease

Glenda Halliday et al.

ACTA NEUROPATHOLOGICA (2008)

添加到收藏夹

Article Clinical Neurology

Occurrence and clinical correlates of REM sleep behaviour disorder in patients with Parkinson's disease over time

M. D. Gjerstad et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)

添加到收藏夹

Article Clinical Neurology

Manifestations of Parkinson disease differ in association with REM sleep behavior disorder

Ronald B. Postuma et al.

MOVEMENT DISORDERS (2008)

添加到收藏夹

Article Clinical Neurology

The REM sleep behavior disorder screening questionnaire -: A new diagnostic instrument

Karin Stiasny-Kolster et al.

MOVEMENT DISORDERS (2007)

添加到收藏夹

Article Clinical Neurology

Positron emission tomography in premotor Parkinson's disease

A. Jon Stoessl

PARKINSONISM & RELATED DISORDERS (2007)

添加到收藏夹

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)

添加到收藏夹

Article Clinical Neurology

REM sleep behavior disorder in sleep-disordered patients with versus without Parkinson's disease:: is there a need for polysomnography?

I Eisensehr et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2001)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.