Insight into the uptake, translocation, metabolism, dissipation and risk assessment of tolfenpyrad in romaine and edible amaranth grown in hydroponic conditions

Tolfenpyrad is an alternative to highly water-soluble and ecotoxic insecticides that is widely used in China. It is absorbed and accumulates in vegetables, leading to potential public-health hazards. A systematic study of the fate of tolfenpyrad is necessary for proper application and food safety. Herein, we report on the uptake, trans location, metabolism, dissipation, and dietary risks of tolfenpyrad in hydroponic romaine and amaranth plants. Roots easily absorbed and accumulated tolfenpyrad, although transport was moderate in both vegetables. Basipetal translocation of tolfenpyrad occurred in romaine but not in edible amaranth, owing to differences in specific transport behaviour in each case. Six metabolites and three pathways were proposed. Tolfenpyrad affected antioxidant enzyme activities in different parts of the two vegetables. Tolfenpyrad dissipation proceeded swiftly, entailing an acceptable risk to humans. Our results provide information on the distribution and transport of tolfenpyrad, as well as on the safety in using it on vegetables.

Automated summary

This study investigated the uptake, translocation, metabolism, dissipation, and dietary risks of tolfenpyrad in hydroponic romaine and amaranth plants. The results showed that tolfenpyrad was easily absorbed and accumulated in the roots of both vegetables, with basipetal translocation occurring in romaine but not in amaranth. Six metabolites and three metabolic pathways were proposed. Tolfenpyrad dissipated quickly, posing an acceptable risk to human health.