☆ 4.4 Review

Development and validation of a novel fetal vesico-amniotic shunt, the vortex shunt

PRENATAL DIAGNOSIS (2023)

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Prenatal diagnosis and outcome of fetal urinomas in relation to the underlying etiology

Corinna Simonini et al.

Summary: This study is a retrospective analysis of pregnancies with prenatally diagnosed fetal urinoma in a single center over a 20-year period. The findings showed that lower urinary tract obstruction (LUTO) and ureteropelvic or ureterovesical junction obstruction (UPJO/UVJO) were the main causes of fetal urinoma. Postnatally, loss of function (LOF) in the affected kidney was more common in UPJO/UVJO cases than in LUTO cases. The prognosis for survivors with UPJO/UVJO urinoma is excellent if the contralateral kidney is normal, while the long-term prognosis for LUTO cases depends on postnatal renal and pulmonary function.

PRENATAL DIAGNOSIS (2023)

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Article Genetics & Heredity

Development and in-vitro characterization of a novel fetal vesicoamniotic shunt - The Vortex shunt

Kunj R. Sheth et al.

Summary: The aim of this study was to develop and test a new vesicoamniotic shunt for the treatment of fetal lower urinary tract obstruction. The results showed that the novel shunt had a higher resistance to dislodgement, easy deployment with ultrasound guidance, and accurate measurement of valve pressure. Further testing in preclinical animal models is currently underway.

PRENATAL DIAGNOSIS (2022)

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Article Pediatrics

Vesico-amniotic shunt insertion prior to the completion of 16 weeks results in improved preservation of renal function in surviving fetuses with isolated severe lower urinary tract obstruction (LUTO)

Thomas Kohl et al.

Summary: The purpose of this retrospective cohort study was to compare the outcomes of human fetuses with isolated severe lower urinary tract obstructions (LUTO) first treated before 16 weeks of gestation to those treated later in gestation. The study found that early intervention before 16 weeks of gestation may result in a higher rate of normal renal and pulmonary function in surviving fetuses.

JOURNAL OF PEDIATRIC UROLOGY (2022)

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Article Pediatrics

Chronic Kidney Disease in Children

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PEDIATRIC CLINICS OF NORTH AMERICA (2022)

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Review Biochemistry & Molecular Biology

Chronic Kidney Disease in Boys with Posterior Urethral Valves-Pathogenesis, Prognosis and Management

Richard Klaus et al.

Summary: Posterior urethral valves are the most common form of lower urinary tract obstructions, causing irreversible damage to kidney and bladder development. Patients often develop chronic kidney disease and bladder dysfunction. The prognosis of these patients depends on prenatal and postnatal parameters.

BIOMEDICINES (2022)

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Review Pediatrics

Therapeutic intervention for fetal lower urinary tract obstruction: Current evidence and future strategies

Marie-Klaire Farrugia et al.

Summary: In-utero vesica-amniotic shunting for fetal lower urinary obstruction (LUTO) can improve perinatal survival, but carries significant risks requiring careful patient selection and timing. Improving the accuracy of prenatal diagnosis and identifying potential risk factors for fetal and postnatal renal failure are essential. When selecting the timing for intervention, various factors need to be considered, especially if the goal is renal preservation.

JOURNAL OF PEDIATRIC UROLOGY (2021)

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Article Pediatrics

Long-Term Renal Transplant Outcome in Patients With Posterior Urethral Valves. Prognostic Factors Related to Bladder Dysfunction Management

Maria Virginia Amesty et al.

Summary: Optimal bladder dysfunction treatment, including CIC with or without a Mitrofanoff procedure, might result in better long-term graft survival in patients with PUV. These procedures were not related to a worse RT outcome in spite of being associated with more frequent UTIs.

FRONTIERS IN PEDIATRICS (2021)

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Article Obstetrics & Gynecology

Fetal Cystoscopy and Vesicoamniotic Shunting in Lower Urinary Tract Obstruction: Long-Term Outcome and Current Technical Limitations

Nicolas Vinit et al.

FETAL DIAGNOSIS AND THERAPY (2020)

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Article Obstetrics & Gynecology

Fetal bladder outflow obstruction: Interventions, outcomes and management uncertainties

Marie-Klaire Farrugia

EARLY HUMAN DEVELOPMENT (2020)

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Article Acoustics

Fetal megacystis: a lot more than LUTO

F. Fontanella et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2019)

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Article Acoustics

Outcome of fetuses with lower urinary tract obstruction and normal amniotic fluid volume in second trimester of pregnancy

A. A. Nassr et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2019)

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Review Obstetrics & Gynecology

Successful in utero Percutaneous Fetoscopic Release of a Wrapped Pleuro-Amniotic Shunt around the Fetal Arm: Case Report and Review of the Literature

Ahmed A. Nassr et al.

FETAL DIAGNOSIS AND THERAPY (2018)

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Article Obstetrics & Gynecology

Natural History of Fetal Lower Urinary Tract Obstruction with Normal Amniotic Fluid Volume at Initial Diagnosis

Mark P. Johnson et al.

FETAL DIAGNOSIS AND THERAPY (2018)

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Article Pediatrics

The ethics of maternal-fetal surgery

Frank A. Chervenak et al.

SEMINARS IN FETAL & NEONATAL MEDICINE (2018)

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Article Obstetrics & Gynecology

Prognosis of Isolated First-Trimester Fetal Megacystis with Spontaneous Resolution

Noemie Girard et al.

FETAL DIAGNOSIS AND THERAPY (2017)

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Review Acoustics

Effectiveness of vesicoamniotic shunt in fetuses with congenital lower urinary tract obstruction: an updated systematic review and meta-analysis

A. A. Nassr et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2017)

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Review Pediatrics

Fetal megacystis: A systematic review

K. Taghavi et al.

JOURNAL OF PEDIATRIC UROLOGY (2017)

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Article Genetics & Heredity

Are ultrasound renal aspects associated with urinary biochemistry in fetuses with lower urinary tract obstruction

Ahmed A. Nassr et al.

PRENATAL DIAGNOSIS (2016)

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Article Acoustics

Fetal lower urinary tract obstruction: proposal for standardized multidisciplinary prenatal management based on disease severity

R. Ruano et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2016)

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Article Acoustics

Urological fistulas after fetal cystoscopic laser ablation of posterior urethral valves: surgical technical aspects

N. Sananes et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2015)

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Article Pediatrics

Can a pressure-limited V-A shunt for obstructive uropathy really protect the kidney?

Kunihide Tanaka et al.

JOURNAL OF PEDIATRIC SURGERY (2014)

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Article Health Care Sciences & Services

Fetal bladder obstruction and its treatment

R. K. Morris et al.

HEALTH TECHNOLOGY ASSESSMENT (2013)

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Article Pediatrics

Outcomes of fetuses with lower urinary tract obstruction treated with vesicoamniotic shunt: A single-institution experience

Cecilia G. Ethun et al.

JOURNAL OF PEDIATRIC SURGERY (2013)

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Article Multidisciplinary Sciences

Evaluation of the Cost Effectiveness of Vesico-Amniotic Shunting in the Management of Congenital Lower Urinary Tract Obstruction (Based on Data from the PLUTO Trial)

Lavanya Diwakar et al.

PLOS ONE (2013)

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Article Obstetrics & Gynecology

Long-term renal and neurodevelopmental outcome in infants with LUTO, with and without fetal intervention

R. Katie Morris et al.

EARLY HUMAN DEVELOPMENT (2011)

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Article Acoustics

Early fetal cystoscopy for first-trimester severe megacystis

R. Ruano et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2011)

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Article Obstetrics & Gynecology

Fetal Lower Urinary Tract Obstruction

Serena Wu et al.

CLINICS IN PERINATOLOGY (2009)

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Article Urology & Nephrology

Early Valve Ablation Can Decrease the Incidence of Bladder Dysfunction in Boys With Posterior Urethral Valves

Mohamed Youssif et al.

JOURNAL OF UROLOGY (2009)

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Article Acoustics

Correlation between ultrasound and anatomical findings in fetuses with lower urinary tract obstruction in the first half of pregnancy

R Robyr et al.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2005)

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Article Genetics & Heredity

Diagnosis and outcome of fetal lower urinary tract obstruction in the northern region of England

DO Anumba et al.

PRENATAL DIAGNOSIS (2005)

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Article Pediatrics

Optimal timing of prenatal treatment of obstructive uropathy in the fetal lamb

H Kitagawa et al.

JOURNAL OF PEDIATRIC SURGERY (2003)

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