4.7 Article

Annickia affinis (Exell) Versteegh & Sosef methanol stem bark extract, potent fractions and isolated Berberine alkaloid target both blood and liver stages of malaria parasites

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Plant Sciences

Antiplasmodial and antimalarial evaluation of a Nigerian hepta-herbal Agbo-iba decoction: Identification of magic bullets and possible facilitators of drug action

Nekpen Erhunse et al.

Summary: This study assessed the safety and efficacy of a herbal mixture used for the management of malaria in Benin city, Nigeria. The results showed that the mixture had a moderate inhibitory effect on malaria parasites and was safe at a certain dosage in mice. Further analysis suggested the presence of synergistic components in the herbal formula, and the identification of a plant with strong anti-malarial activity.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

Review Pharmacology & Pharmacy

Protecting future antimalarials from the trap of resistance: Lessons from artemisinin-based combination therapy (ACT) failures

Nekpen Erhunse et al.

Summary: Cambodia switched from dihydroartemisinin-piperaquine to artesunate-mefloquine as first-line therapy due to parasite resistance, but now faces triple mutant strains, indicating the need for alternative treatment strategies. Proper understanding of contributors to artemisinin resistance is essential for identifying novel strategies to combat resistance and protect future antimalarial drugs.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2021)

Article Chemistry, Multidisciplinary

Multistage antiplasmodial activity of hydroxyethylamine compounds,in vitroandin vivoevaluations

Neha Sharma et al.

RSC ADVANCES (2020)

Article Pharmacology & Pharmacy

Drugs in Development for Malaria

Elizabeth A. Ashley et al.

Article Biochemistry & Molecular Biology

Protoberberine Isoquinoline Alkaloids from Arcangelisia gusanlung

Ling-Ling Yu et al.

MOLECULES (2014)

Review Biochemistry & Molecular Biology

Alkaloids from the Tribe Bocconieae (Papaveraceae): A Chemical and Biological Review

Xuelong Yu et al.

MOLECULES (2014)

Article Multidisciplinary Sciences

Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats

Xiang-Shan Tan et al.

PLOS ONE (2013)

Article Medicine, General & Internal

Artemisinin Resistance in Plasmodium falciparum Malaria.

Arjen M. Dondorp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Biochemistry & Molecular Biology

Quaternary protoberberine alkaloids

Lenka Grycova et al.

PHYTOCHEMISTRY (2007)

Review Pharmacology & Pharmacy

Transporters involved in resistance to antimalarial drugs

Stephanie G. Valderramos et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2006)

Article Parasitology

Contribution of the pfmdr1 gene to antimalarial drug-resistance

MT Duraisingh et al.

ACTA TROPICA (2005)

Article Microbiology

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening

M Smilkstein et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Immunology

Chloroquine-resistant malaria

TE Wellems et al.

JOURNAL OF INFECTIOUS DISEASES (2001)