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注意：仅列出部分参考文献，下载原文获取全部文献信息。The One-Hundred-Year Anniversary of the Discovery of the Sunshine Vitamin D3: Historical, Personal Experience and Evidence-Based Perspectives
Michael F. F. Holick
NUTRIENTS (2023)
Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3
Pawel Brzeminski et al.
BIOORGANIC CHEMISTRY (2022)
Efficient Asymmetric Synthesis of an A-Ring Synthon for Pd-Catalyzed Preparation of 1α-Hydroxyvitamin D Metabolites and Analogs
Julian Loureiro et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2022)
Convergent total synthesis of (+)-calcipotriol: A scalable, modular approach to vitamin D analogs
Jieyu Gu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25
Samuel Seoane et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17
Ramon Fraga et al.
CHEMISTRY-A EUROPEAN JOURNAL (2021)
Strategies for the Synthesis of 19-nor-Vitamin D Analogs
Susana Fernandez et al.
PHARMACEUTICALS (2020)
25-Hydroxyvitamin D status, vitamin D intake, and skin cancer risk: a systematic review and dose-response meta-analysis of prospective studies
Yahya Mahamat-Saleh et al.
SCIENTIFIC REPORTS (2020)
Vitamin D and its analogs as anticancer and anti-inflammatory agents
Jingxuan Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Vitamin D and Its Synthetic Analogs
Miguel A. Maestro et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Non-Skeletal Activities of Vitamin D: From Physiology to Brain Pathology
Giulia Bivona et al.
MEDICINA-LITHUANIA (2019)
Update on pharmacologically-relevant vitamin D analogues
Glenville Jones et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2019)
Studies on the Synthesis of Vitamin D Analogs with Aromatic D-Ring
Silvina Eduardo-Canosa et al.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2018)
Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium
Diego Carballa et al.
CHEMISTRY-A EUROPEAN JOURNAL (2018)
Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists
Pranjal Gogoi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
25S-Adamanty1-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex
Rocio Otero et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Total synthesis of 1,25-dihydroxyvitamin D3 analogs modified at the side chain and D-ring
Borja Lopez-Perez et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2018)
Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group
Rita Sigueiro et al.
ORGANIC LETTERS (2018)
The discovery and synthesis of the nutritional factor vitamin D
Glenville Jones
INTERNATIONAL JOURNAL OF PALEOPATHOLOGY (2018)
Total synthesis of 1α, 25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution
Borja Lopez-Perez et al.
CHEMICAL COMMUNICATIONS (2017)
Is Vitamin D2 Really Bioequivalent to Vitamin D3?
Roger Bouillon et al.
ENDOCRINOLOGY (2016)
Vitamin D receptor 2016: novel ligands and structural insights
Miguel A. Maestro et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
Stereoselective synthesis of 1β,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative
Julian Loureiro et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
Carborane-based design of a potent vitamin D receptor agonist
Rocio Otero et al.
CHEMICAL SCIENCE (2016)
Synthesis of 1 α- and 1 β-amino-25-hydroxyvitamin D3
Yusuke Akagi et al.
ASIAN JOURNAL OF ORGANIC CHEMISTRY (2016)
Novel 9-Alkyl- and 9-Alkylidene-Substituted 1α,25-Dihydroxyvitamin D3 Analogues: Synthesis and Biological Examinations
Urszula Kulesza et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
An efficient convergent synthesis of 1α,25-dihydroxy-3-epi-vitamin D2
Rita Sigueeiro et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Synthesis and biological activities of vitamin D3 derivatives with cyanoalkyl side chain at C-2 position
Hiroshi Saitoh et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Synthesis and Biological Activity of Two C-7 Methyl Analogues of Vitamin D
Katarzyna Sokolowska et al.
JOURNAL OF ORGANIC CHEMISTRY (2015)
Retiferols - synthesis and biological activity of a conceptually novel class of vitamin D analogs
Narasimha Rao Bolla et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
The future of vitamin D analogs
Carlien Leyssens et al.
FRONTIERS IN PHYSIOLOGY (2014)
Synthesis of 1α,25-dihydroxyvitamin D3 analogues with α-hydroxyalkyl substituents at C12
Diego M. Carballa et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)
An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3
R. Fraga et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)
Synthesis of novel C-2 substituted vitamin D derivatives having ringed side chains and their biological evaluation on bone
Hiroshi Saito et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)
Synthesis of 2α-Heteroarylalkyl Active Vitamin D3 with Therapeutic Effect on Enhancing Bone Mineral Density in Vivo
Mild Matsuo et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
The History of the Discovery of Vitamin D and Its Daughter Steroid Hormone
Anthony W. Norman
ANNALS OF NUTRITION AND METABOLISM (2012)
A-ring analogs of 1,25-dihydroxyvitamin D3
Agnieszka Glebocka et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
Design, Synthesis, Evaluation, and Structure of Vitamin D Analogues with Furan Side Chains
Ramon Fraga et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
Editorial [ Hot Topic:Organic Synthesis Using Green Reaction Media (Guest Editors: Devdutt Chaturvedi and Nabin C. Barua)]
Devdutt Chaturvedi et al.
CURRENT ORGANIC SYNTHESIS (2012)
Synthesis of (1a)-1,25-Dihydroxyvitamin D3 with a ß-Positioned Seven-Carbon Side Chain at C(12)
Diego M. Carballa et al.
HELVETICA CHIMICA ACTA (2012)
Synthesis and Biological Evaluation of 1α,25-Dihydroxyvitamin D3 Analogues with a Long Side Chain at C12 and Short C17 Side Chains
Diego M. Carballa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Fluoride-Mediated Elimination of Allyl Sulfones: Application to the Synthesis of a 2,4-Dimethyl-A-ring Vitamin D3 Analogue
Vikas Sikervar et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Advances in the Synthesis of A-Ring 1,7-Enyne Synthons for Active Vitamin D3 Analogues
Yi-Zhen Yin et al.
CURRENT ORGANIC SYNTHESIS (2011)
Development of 14-epi-19-Nortachysterol and Its Unprecedented Binding Configuration for the Human Vitamin D Receptor
Daisuke Sawada et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
New C15-Substituted Active Vitamin D3
Kanako Shindo et al.
ORGANIC LETTERS (2011)
1α,25(OH)2-3-Epi-Vitamin D3, a Natural Physiological Metabolite of Vitamin D3: Its Synthesis, Biological Activity and Crystal Structure with Its Receptor
Ferdinand Molnar et al.
PLOS ONE (2011)
An Expeditious Route to 1 alpha,25-Dihydroxyvitamin D-3 and Its Analogues by an Aqueous Tandem Palladium-Catalyzed A-Ring Closure and Suzuki Coupling to the C/D Unit
Pranjal Gogoi et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution
Sreeram V. Ramagopalan et al.
GENOME RESEARCH (2010)
Structure-Function Relationships and Crystal Structures of the Vitamin D Receptor Bound 2α-Methyl-(20S,23S)- and 2α-Methyl-(20S,23R)-epoxymethano-1α,25-dihydroxyvitamin D3
Pierre Antony et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Design and synthesis of active vitamin D analogs
Silvina Eduardo-Canosa et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Synthesis and biological evaluation of 6-methyl analog of 1α,25-dihydroxyvitannin D3
Katarzyna Sokolowska et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Synthesis of a 1α-C-methyl analogue of 25-hydroxyvitamin D3: interaction with a mutant vitamin D receptor Arg274Leu
Shinobu Honzawa et al.
TETRAHEDRON (2009)
Enantioselective synthesis of steroids
Anne-Sophie Chapelon et al.
TETRAHEDRON (2007)
Further synthetic and biological studies on vitamin D hormone antagonists based on C24-alkylation and C2α-functionalization of 25-dehydro-1α-hydroxyvitamin D3-26,23-lactones
Nozomi Saito et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Pd-catalyzed carbocyclization-Negishi cross-coupling cascade:: A novel approach to 1α,25-dihydroxyvitamin D3 and analogues
C Gómez-Reino et al.
ORGANIC LETTERS (2005)
Design and efficient synthesis of 2α-(ω-hydroxyalkoxy)-1α,25-dihydroxyvitamin D3 analogues, including 2-epi-ED-71 and their 20-epimers with HL-60 cell differentiation activity
N Saito et al.
JOURNAL OF ORGANIC CHEMISTRY (2004)
New convergent synthesis of 1α,25-dihydroxyvitamin D3 and its analogues by Suzuki-Miyaura coupling between A-ring and C,D-ring parts
T Hanazawa et al.
JOURNAL OF ORGANIC CHEMISTRY (2003)
Dramatic enhancement of antagonistic activity on vitamin D receptor:: A double functionalization of 1α-hydroxyvitamin D3 26,23-lactones
N Saito et al.
ORGANIC LETTERS (2003)
Efficient convergent synthesis of 1α,25-dihydroxyvitamin D3 and its analogues by Suzuki-Miyaura coupling. (vol 5, pg 524, 2003)
T Hanazawa et al.
ORGANIC LETTERS (2003)
Efficient synthesis of the A-ring phosphine oxide building block useful for 1α,25-dihydroxy vitamin D3 and analogues
AR Daniewski et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Efficient and versatile synthesis of novel 2α-substituted 1α,25-dihydroxyvitamin D3 analogues and their docking to vitamin D receptors
Y Suhara et al.
JOURNAL OF ORGANIC CHEMISTRY (2001)
A concise enantioselective synthesis of a key A-ring synthon for 1α-hydroxyvitamin D3 compounds
H Hiyamizu et al.
ORGANIC LETTERS (2001)
Synthesis and evaluation of A-ring diastereomers of 1α,25-dihydroxy-22-0xavitamin D3 (OCT)
S Hatakeyama et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2001)
A concise and efficient route to 2α-(ω-hydroxyalkoxy)-1α,25-dihydroxyvitamin D3:: Remarkably high affinity to vitamin D receptor
A Kittaka et al.
ORGANIC LETTERS (2000)
Synthesis of vitamin D analogues with a 2-hydroxy-3-deoxy ring A
EM Codesido et al.
TETRAHEDRON LETTERS (2000)
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