Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference

Review Pediatrics

Neonatal fluid overload-ignorance is no longer bliss

Lucinda J. Weaver et al.

Summary: This article discusses the impact of excessive fluid accumulation on neonates and its related pathophysiology, and provides clinical recommendations for monitoring, prevention, and treatment of fluid overload.

PEDIATRIC NEPHROLOGY (2023)

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Article Pediatrics

Adaptive Clinical Trials in Pediatric Critical Care: A Systematic Review

Patricia Gilholm et al.

Pediatric Critical Care Medicine (2023)

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Article Pediatrics

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Matthew F. Barhight et al.

Summary: The study showed that excessive non-resuscitation fluid given to critically ill children was associated with higher in-hospital mortality. Excess maintenance fluid is a modifiable contributor to this fluid volume and strategies to reduce excess maintenance fluids warrant further study.

PEDIATRIC RESEARCH (2022)

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Article Cardiac & Cardiovascular Systems

Fluid Accumulation After Neonatal Congenital Cardiac Operation: Clinical Implications and Outcomes

David K. Bailly et al.

Summary: This study aimed to investigate the association between fluid balance metrics and mortality and postoperative outcomes in neonatal cardiac operation. The results showed that time to first negative daily fluid balance was associated with improved postoperative outcomes, while percentage fluid overload was not. Therefore, specific treatments to achieve an early negative fluid balance may reduce postoperative care durations.

ANNALS OF THORACIC SURGERY (2022)

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Article Critical Care Medicine

Components of Health-Related Quality of Life Most Affected Following Pediatric Critical Illness

Elizabeth Y. Killien et al.

Summary: The study aims to evaluate the decline in health-related quality of life following pediatric critical care and determine which individual elements contribute most to this decline. The findings suggest that emotional, physical, energy, activity, sleep, and fear categories are commonly affected. Patient age and baseline health status were also found to impact the risk of decline.

CRITICAL CARE MEDICINE (2022)

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Article Pediatrics

Prospective Cohort Study on Cumulative Fluid Balance and Outcome in Critically Ill Children Using a Restrictive Fluid Protocol

Ramachandran Rameshkumar et al.

Summary: This prospective cohort study examined the association between cumulative fluid balance and clinical outcomes in a pediatric intensive care unit practicing a restrictive fluid protocol. The study found that there was no significant difference in PICU mortality and morbidity among patients with cumulative fluid balance within 3%. However, patients with positive fluid balance had a longer stay in the intensive care unit and hospital.

INDIAN JOURNAL OF PEDIATRICS (2022)

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Article Pediatrics

Patient-centered outcomes in pediatric continuous kidney replacement therapy: new morbidity and worsened functional status in survivors

Mallory Smith et al.

Summary: A retrospective cohort study on pediatric CKRT survivors revealed high rates of new morbidity and worse functional outcomes at PICU discharge, highlighting the necessity for targeted follow-up for this vulnerable population. Further research is needed to investigate deliberate decrease of sedation exposure as a modifiable risk factor for these patients.

PEDIATRIC NEPHROLOGY (2022)

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Article Urology & Nephrology

Integration of the Renal Angina Index and Urine Neutrophil Gelatinase-Associated Lipocalin Improves Severe Acute Kidney Injury Prediction in Critically Ill Children and Young Adults

Stuart L. Goldstein et al.

Summary: Acute kidney injury is common among children and young adults admitted to the pediatric intensive care unit, and severe acute kidney injury is associated with mortality. The integration of renal angina index and urine NGAL improves the prediction of severe acute kidney injury.

KIDNEY INTERNATIONAL REPORTS (2022)

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Article Urology & Nephrology

Optimizing the Design and Analysis of Future AKI Trials

Matthieu Legrand et al.

Summary: This article reviews the barriers to and strategies for improving clinical trial design and implementation in AKI patients, proposing novel approaches such as adaptive trial designs, pragmatic trial designs, and platform trial designs. It also covers new approaches to clinical trial analysis and provides a roadmap for future trial planning.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2022)

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Article Pediatrics

Assessment of fluid balance after neonatal cardiac surgery: a description of intake/output vs. weight-based methods

Tara M. Neumayr et al.

Summary: Weighing neonates early after cardiac surgery is uncommon, with significant practice variation among centers. There is weak correlation between intake/output-based fluid balance and weight change-based fluid balance, and further study is needed to determine which metric is most associated with adverse outcomes.

PEDIATRIC NEPHROLOGY (2022)

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Article Medicine, General & Internal

Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children A Modified Delphi Consensus Statement

Stuart L. Goldstein et al.

Summary: Increasing evidence suggests that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor outcomes. This study aimed to develop expert-driven recommendations to expand pediatric AKI knowledge. The meeting resulted in 12 consensus statements and 29 research recommendations, highlighting the need to include data from diverse socioeconomic groups, broaden the definition of AKI, integrate the biological pathophysiology of child growth and development, and engage with families and communities in AKI advocacy.

JAMA NETWORK OPEN (2022)

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Article Cardiac & Cardiovascular Systems

Prophylactic Peritoneal Dialysis After the Arterial Switch Operation: A Retrospective Cohort Study

Katja M. Gist et al.

Summary: A study on neonates undergoing the arterial switch operation found that prophylactic peritoneal dialysis can improve postoperative outcomes by reducing mechanical ventilation hours, intensive care unit length of stay, and hospital costs.

ANNALS OF THORACIC SURGERY (2021)

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Review Obstetrics & Gynecology

Improving the quality of neonatal acute kidney injury care: neonatal-specific response to the 22nd Acute Disease Quality Initiative (ADQI) conference

Matthew W. Harer et al.

Summary: With the adoption of standardized neonatal AKI definitions and increased research, the epidemiology and risk factors of neonatal AKI are now better understood. Focus is now shifting towards strategies to improve AKI care processes and reduce associated morbidity and mortality. Challenges in translating adult AKI quality improvement concepts to neonates require specific neonatal-specific responses from experts in the field.

JOURNAL OF PERINATOLOGY (2021)

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Article Critical Care Medicine

Timing of Fluid Overload and Association With Patient Outcome

Lisa Lima et al.

Summary: This study aimed to determine if the timing of excess fluid accumulation is associated with adverse patient outcomes. The results showed that peak fluid overload value after 48 hours of ICU admission was related to longer ICU and hospital stays, as well as increased risk of mortality.

PEDIATRIC CRITICAL CARE MEDICINE (2021)

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Article Pediatrics

Factors associated with mortality of pediatric sepsis patients at the pediatric intensive care unit in a low-resource setting

Desy Rusmawatiningtyas et al.

Summary: This study retrospectively analyzed the records of patients diagnosed with sepsis and admitted to PICU between 2014 and 2019 in a tertiary hospital. The study found that over half of the patients died during the study period, with mortality risk associated with factors such as fluid overload, need for mechanical ventilation support, vasoactive drugs, and congenital anomalies.

BMC PEDIATRICS (2021)

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Editorial Material Pediatrics

Quality improvement goals for pediatric acute kidney injury: pediatric applications of the 22nd Acute Disease Quality Initiative (ADQI) conference

David T. Selewski et al.

PEDIATRIC NEPHROLOGY (2021)

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Article Pediatrics

Advances in Neonatal Acute Kidney Injury

Michelle C. Starr et al.

Summary: Significant advances have been made in the field of neonatal acute kidney injury over the past 5 years, with large multicenter studies revealing the association of AKI with increased morbidity and mortality. Preventive strategies and new technologies have shown promise in the management of AKI, and there is a growing recognition of the importance of kidney function in the development and injury of other organs. Future research is needed to focus on optimal follow-up strategies for neonates with a history of AKI to detect chronic kidney disease.

PEDIATRICS (2021)

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Article Pediatrics

Higher total ultrafiltration volume during cardiopulmonary bypass-assisted infant cardiac surgery is associated with acute kidney injury and fluid overload

Dominic Zanaboni et al.

Summary: The study found that judicious use of UF in more complex congenital cardiac surgery reduces the risk of AKI. Patients with a higher incidence of AKI took longer to achieve negative fluid balance, and patients undergoing more complex surgeries had a higher risk of developing AKI.

PEDIATRIC NEPHROLOGY (2021)

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Article Critical Care Medicine

Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial

Suvi T. Vaara et al.

Summary: In critically ill patients with AKI, a restrictive fluid management strategy resulted in lower cumulative fluid balance and reduced need for renal replacement therapy compared to usual care, with less adverse events reported in the restrictive fluid management group. Larger trials of this intervention are warranted to further evaluate its effectiveness.

INTENSIVE CARE MEDICINE (2021)

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Article Critical Care Medicine

Continuous Renal-Replacement Therapy in Critically Ill Children: Practice Changes and Association With Outcome

ZhiJiang Chen et al.

Summary: This study evaluated practice changes and outcomes of critically ill children receiving continuous renal-replacement therapy in a large single-center PICU over a 10-year period. The study found improvements in patient survival rate by implementing early initiation of therapy, reducing fluid overload, and using regional citrate anticoagulation. Ongoing evaluation and quality improvement in the practice of continuous renal-replacement therapy for pediatric patients is still needed.

PEDIATRIC CRITICAL CARE MEDICINE (2021)

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Article Critical Care Medicine

Timing and Clinical Significance of Fluid Overload in Pediatric Acute Respiratory Distress Syndrome*

Celeste G. Black et al.

Summary: This retrospective cohort study analyzed data of 723 intubated children with acute respiratory distress syndrome between 2011 and 2019 in a single tertiary care PICU. The study found that fluid overload after day 4 of acute respiratory distress syndrome onset was associated with worse outcomes. Elevated angiopoietin-2 levels predicted subsequent fluid overload.

PEDIATRIC CRITICAL CARE MEDICINE (2021)

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Review Health Care Sciences & Services

Health-related quality of life outcome measures for children surviving critical care: a scoping review

Elizabeth Y. Killien et al.

Summary: The study found that the commonly used HRQL instruments in pediatric critical care research are limited by minimal longitudinal follow-up and infrequent assessment of baseline HRQL.

QUALITY OF LIFE RESEARCH (2021)

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Review Pediatrics

Outcome Measures Following Critical Illness in Children With Disabilities: A Scoping Review

Julia A. Heneghan et al.

Summary: This study addresses the challenges and importance of measuring long-term outcomes in children with disabilities who have been admitted to the PICU. Through a mixed methodology approach, the researchers identified and described assessment tools for this population, as well as highlighted areas for future instrument development.

FRONTIERS IN PEDIATRICS (2021)

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Article Pediatrics

Post-operative fluid overload as a predictor of hospital and long-term outcomes in a pediatric heart transplant population

Nicole M. Anderson et al.

Summary: The study found that fluid overload is common after pediatric heart transplant and is associated with worse clinical outcomes. Shorter donor ischemic time and longer cardiopulmonary bypass time may increase the risk of fluid overload. Fluid overload greater than 20% is a statistically significant independent predictor of mortality, ventilation time, and PICU length of stay.

PEDIATRIC TRANSPLANTATION (2021)

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Article Engineering, Biomedical

Acute Kidney Injury, Fluid Overload, and Outcomes in Children Supported With Extracorporeal Membrane Oxygenation for a Respiratory Indication

Palen P. Mallory et al.

ASAIO JOURNAL (2020)

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Article Critical Care Medicine

Assessment of the Independent and Synergistic Effects of Fluid Overload and Acute Kidney Injury on Outcomes of Critically Ill Children*

Katja M. Gist et al.

PEDIATRIC CRITICAL CARE MEDICINE (2020)

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Article Pediatrics

The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group

David T. Selewski et al.

PEDIATRIC RESEARCH (2020)

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Article Anesthesiology

Fluid Overload in Special Pediatric Cohorts With Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery Following Surgical Repair

Jianhui Wang et al.

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA (2020)

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Article Pediatrics

Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy: a multicenter retrospective cohort study

Stephen M. Gorga et al.

PEDIATRIC NEPHROLOGY (2020)

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Review Pediatrics

Association of postoperative fluid overload with adverse outcomes after congenital heart surgery: a systematic review and dose-response meta-analysis

Ioannis Bellos et al.

PEDIATRIC NEPHROLOGY (2020)

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Article Critical Care Medicine

Fluid Accumulation in Critically Ill Children*

Rashid Alobaidi et al.

CRITICAL CARE MEDICINE (2020)

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Article Pediatrics

Early fluid overload is associated with mortality and prolonged mechanical ventilation in extremely low birth weight infants

Felipe Yu Matsushita et al.

EUROPEAN JOURNAL OF PEDIATRICS (2020)

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Article Critical Care Medicine

Profile of Fluid Exposure and Recognition of Fluid Overload in Critically Ill Children

Zahraa H. Al-Lawati et al.

PEDIATRIC CRITICAL CARE MEDICINE (2020)

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Article Pediatrics

Effects of hyperchloremia on renal recovery in critically ill children with acute kidney injury

Matthew F. Barhight et al.

PEDIATRIC NEPHROLOGY (2020)

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Article Critical Care Medicine

Severe Acute Kidney Injury Is Associated With Increased Risk of Death and New Morbidity After Pediatric Septic Shock*

Michelle C. Starr et al.

PEDIATRIC CRITICAL CARE MEDICINE (2020)

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Article Pediatrics

The impact of fluid balance on outcomes in critically ill near-term/term neonates: a report from the AWAKEN study group

David T. Selewski et al.

PEDIATRIC RESEARCH (2019)

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Article Pediatrics

Fluid Overload and Kidney Injury Score as a Predictor for Ventilator-Associated Events

Jarin Vaewpanich et al.

FRONTIERS IN PEDIATRICS (2019)

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Article Critical Care Medicine

Mortality of Critically Ill Children Requiring Continuous Renal Replacement Therapy: Effect of Fluid Overload, Underlying Disease, and Timing of Initiation

Gerard Cortina et al.

PEDIATRIC CRITICAL CARE MEDICINE (2019)

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Article Medicine, Research & Experimental

Factors affecting mortality in children requiring continuous renal replacement therapy in pediatric intensive care unit

Monika Miklaszewska et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2019)

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Article Pediatrics

Less Is More?-A Feasibility Study of Fluid Strategy in Critically Ill Children With Acute Respiratory Tract Infection

Sarah A. Ingelse et al.

FRONTIERS IN PEDIATRICS (2019)

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Article Pediatrics

Adverse Outcomes due to Aggressive Fluid Resuscitation in Children: A Prospective Observational Study

Anand Muttath et al.

JOURNAL OF PEDIATRIC INTENSIVE CARE (2019)

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Review Pediatrics

The role of fluid overload in the prediction of outcome in acute kidney injury

David T. Selewski et al.

PEDIATRIC NEPHROLOGY (2018)

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Article Engineering, Biomedical

Implementing a practice change: early initiation of continuous renal replacement therapy during neonatal extracorporeal life support standardizes care and improves short-term outcomes

Heidi J. Murphy et al.

JOURNAL OF ARTIFICIAL ORGANS (2018)

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Article Pediatrics

Fluid overload independent of acute kidney injury predicts poor outcomes in neonates following congenital heart surgery

Kenneth E. Mah et al.

PEDIATRIC NEPHROLOGY (2018)

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Article Nutrition & Dietetics

Early Continuous Renal Replacement Therapy Improves Nutrition Delivery in Neonates During Extracorporeal Life Support

Heidi J. Murphy et al.

JOURNAL OF RENAL NUTRITION (2018)

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Article Medicine, General & Internal

Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery

P. S. Myles et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

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Article Pediatrics

Hyperchloremia is independently associated with mortality in critically ill children who ultimately require continuous renal replacement therapy

Matthew F. Barhight et al.

PEDIATRIC NEPHROLOGY (2018)

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Review Pediatrics

Association Between Fluid Balance and Outcomes in Critically Ill Children A Systematic Review and Meta-analysis

Rashid Alobaidi et al.

JAMA PEDIATRICS (2018)

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Article Pediatrics

Fluid Overload and Renal Angina Index at Admission Are Associated With Worse Outcomes in Critically Ill Children

Sidharth K. Sethi et al.

FRONTIERS IN PEDIATRICS (2018)

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Article Engineering, Biomedical

Long-duration (>4 Weeks) Continuous Renal Replacement Therapy in Critical Illness

J. Scott Baird et al.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS (2018)

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Article Medicine, General & Internal

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial

Lauralyn McIntyre et al.

BMJ OPEN (2018)

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Article Pediatrics

Association of Fluid Overload with Mortality in Critically-ill Mechanically Ventilated Children

Sukla Samaddar et al.

INDIAN PEDIATRICS (2018)

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Article Critical Care Medicine

Increase in chloride from baseline is independently associated with mortality in critically ill children

Matthew F. Barhight et al.

INTENSIVE CARE MEDICINE (2018)

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Article Cardiac & Cardiovascular Systems

Acute Kidney Injury Defined by Fluid Corrected Creatinine in Neonates After the Norwood Procedure

Megan McFerson SooHoo et al.

WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY (2018)

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Article Critical Care Medicine

Fluid overload and outcomes in critically ill children: A single center prospective cohort study

Franco Diaz et al.

JOURNAL OF CRITICAL CARE (2017)

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Article Critical Care Medicine

Continuous Venovenous Hemofiltration in Children Less Than or Equal to 10 kg: A Single-Center Experience

Siree Kaempfen et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Critical Care Medicine

Factors Associated With Mortality in Continuous Renal Replacement Therapy for Pediatric Patients With Acute Kidney Injury

Seung Jun Choi et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Critical Care Medicine

Early Fluid Overload Prolongs Mechanical Ventilation in Children With Viral-Lower Respiratory Tract Disease

Sarah A. Ingelse et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Critical Care Medicine

Fluid Overload and Kidney Injury Score: A Multidimensional Real-Time Assessment of Renal Disease Burden in the Critically III Patient

Ayse Akcan-Arikan et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Critical Care Medicine

A Case-Control Analysis of Postoperative Fluid Balance and Mortality After Pediatric Cardiac Surgery

Meth R. Delpachitra et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Critical Care Medicine

The Impact of Fluid Overload on Outcomes in Children Treated With Extracorporeal Membrane Oxygenation: A Multicenter Retrospective Cohort Study*

David T. Selewski et al.

PEDIATRIC CRITICAL CARE MEDICINE (2017)

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Article Pediatrics

Peritoneal Dialysis vs Furosemide for Prevention of Fluid Overload in Infants After Cardiac Surgery A Randomized Clinical Trial

David M. Kwiatkowski et al.

JAMA PEDIATRICS (2017)

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Article Pediatrics

Early fluid overload is associated with acute kidney injury and PICU mortality in critically ill children

Yanhong Li et al.

EUROPEAN JOURNAL OF PEDIATRICS (2016)

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Article Pediatrics

Continuous renal replacement therapy in children: fluid overload does not always predict mortality

Lara de Galasso et al.

PEDIATRIC NEPHROLOGY (2016)

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Article Critical Care Medicine

Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial

Peter B. Hjortrup et al.

INTENSIVE CARE MEDICINE (2016)

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Article Critical Care Medicine

Fluid Overload Is Associated With Late Poor Outcomes in Neonates Following Cardiac Surgery

Nicole S. Wilder et al.

PEDIATRIC CRITICAL CARE MEDICINE (2016)

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Article Critical Care Medicine

Fluid Overload Is Associated With Higher Mortality and Morbidity in Pediatric Patients Undergoing Cardiac Surgery*

Daniel J. Lex et al.

PEDIATRIC CRITICAL CARE MEDICINE (2016)

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Article Pediatrics

Fluid overload and outcomes in neonates receiving continuous renal replacement therapy

Sang Taek Lee et al.

PEDIATRIC NEPHROLOGY (2016)

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Article Multidisciplinary Sciences

Association of Fluid Accumulation with Clinical Outcomes in Critically Ill Children with Severe Sepsis

Jiao Chen et al.

PLOS ONE (2016)

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Article Medicine, Research & Experimental

A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial

Melissa J. Parker et al.

TRIALS (2016)

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Article Multidisciplinary Sciences

Risk Factors for Acute Kidney Injury after Congenital Cardiac Surgery in Infants and Children: A Retrospective Observational Study

Sun-Kyung Park et al.

PLOS ONE (2016)

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Article Critical Care Medicine

Early fluid accumulation in children with shock and ICU mortality: a matched case-control study

Priya Bhaskar et al.

INTENSIVE CARE MEDICINE (2015)

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Article Cardiac & Cardiovascular Systems

The Influence of Fluid Overload on the Length of Mechanical Ventilation in Pediatric Congenital Heart Surgery

Tatiana Z. A. L. Sampaio et al.

PEDIATRIC CARDIOLOGY (2015)

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Article Critical Care Medicine

Fluid Overload at 48 Hours Is Associated With Respiratory Morbidity but Not Mortality in a General PICU: Retrospective Cohort Study

Lynn Sinitsky et al.

PEDIATRIC CRITICAL CARE MEDICINE (2015)

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Article Pediatrics

Acute kidney injury is associated with bronchopulmonary dysplasia/mortality in premature infants

David Askenazi et al.

PEDIATRIC NEPHROLOGY (2015)

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Article Pediatrics

Assessing fluid balance in critically ill pediatric patients

Thomas Bontant et al.

EUROPEAN JOURNAL OF PEDIATRICS (2015)

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Article Critical Care Medicine

Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial

Zaccaria Ricci et al.

CRITICAL CARE (2015)

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Article Respiratory System

Volume Overload: Prevalence, Risk Factors, and Functional Outcome in Survivors of Septic Shock

Kristina H. Mitchell et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2015)

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Article Cardiac & Cardiovascular Systems

Acute Kidney Injury and Fluid Overload in Neonates Following Surgery for Congenital Heart Disease

Kurt D. Piggott et al.

WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY (2015)

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Article Urology & Nephrology

Incorporation of Biomarkers with the Renal Angina Index for Prediction of Severe AKI in Critically Ill Children

Rajit K. Basu et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)

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Article Critical Care Medicine

Extent, Risk Factors, and Outcome of Fluid Overload After Pediatric Heart Surgery

Jade Seguin et al.

CRITICAL CARE MEDICINE (2014)

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Article Critical Care Medicine

Timing of Continuous Renal Replacement Therapy and Mortality in Critically Ill Children

Vinai Modem et al.

CRITICAL CARE MEDICINE (2014)

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Article Critical Care Medicine

Post-ICU Admission Fluid Balance and Pediatric Septic Shock Outcomes: A Risk-Stratified Analysis

Kamal Abulebda et al.

CRITICAL CARE MEDICINE (2014)

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Article Critical Care Medicine

Indications and outcomes in children receiving renal replacement therapy in pediatric intensive care

Erin D. Boschee et al.

JOURNAL OF CRITICAL CARE (2014)

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Article Pediatrics

Fluid Overload in a South African Pediatric Intensive Care Unit

Naomi Ketharanathan et al.

JOURNAL OF TROPICAL PEDIATRICS (2014)

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Article Urology & Nephrology

Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children

Rajit K. Basu et al.

KIDNEY INTERNATIONAL (2014)

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Article Critical Care Medicine

Early Postoperative Fluid Overload Precedes Acute Kidney Injury and Is Associated With Higher Morbidity in Pediatric Cardiac Surgery Patients

Amanda B. Hassinger et al.

PEDIATRIC CRITICAL CARE MEDICINE (2014)

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Article Pediatrics

Extrarenal sequential organ failure assessment score as an outcome predictor of critically ill children on continuous renal replacement therapy

Won Kyoung Jhang et al.

PEDIATRIC NEPHROLOGY (2014)

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Article Cardiac & Cardiovascular Systems

Prophylactic Peritoneal Dialysis Following Cardiopulmonary Bypass in Children Is Associated with Decreased Inflammation and Improved Clinical Outcomes

William C. Sasser et al.

CONGENITAL HEART DISEASE (2014)

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Article Pediatrics

Relationship Between the Functional Status Scale and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category Scales

Murray M. Pollack et al.

JAMA PEDIATRICS (2014)

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Article Pediatrics

Continuous Renal Replacement Therapy for Children ≤10 kg: A Report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry

David J. Askenazi et al.

JOURNAL OF PEDIATRICS (2013)

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Article Critical Care Medicine

Fluid Overload in Infants Following Congenital Heart Surgery

Matthew A. Hazle et al.

PEDIATRIC CRITICAL CARE MEDICINE (2013)

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Article Pediatrics

Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate

David J. Askenazi et al.

PEDIATRIC NEPHROLOGY (2013)

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Article Critical Care Medicine

Development and Standardization of a Furosemide Stress Test to Predict the Severity of Acute Kidney Injury

Lakhmir S. Chawla et al.

CRITICAL CARE (2013)

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Article Pediatrics

Reliability of the fluid balance in neonates

Yvette van Asperen et al.

ACTA PAEDIATRICA (2012)

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Article Critical Care Medicine

Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy

David T. Selewski et al.

CRITICAL CARE MEDICINE (2012)

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Article Critical Care Medicine

Fluid balance in critically ill children with acute lung injury

Stacey L. Valentine et al.

CRITICAL CARE MEDICINE (2012)

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Article Critical Care Medicine

Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy

Rebecca M. Lombel et al.

INTENSIVE CARE MEDICINE (2012)

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Article Critical Care Medicine

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