☆ 4.7 Review

Comprehending COVID-19 diagnostic tests and greenness assessment of its reported detection methods

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2023)

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Article Chemistry, Analytical

Label free electrochemical DNA biosensor for COVID-19 diagnosis

Atchara Lomae et al.

Summary: The COVID-19 pandemic has accelerated the development of portable diagnostic tools for detecting and controlling the spread of the disease. In this study, a smartphone-assisted Sensit Smart potentiostat was combined with a paper-based electrochemical sensor to detect SARS-CoV-2. The sensor utilized a disposable paper-based device with a modified working electrode that captures the target DNA. The developed sensor demonstrated high specificity and achieved accurate detection of SARS-CoV-2 in patient samples.

TALANTA (2023)

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Article Medicine, Research & Experimental

Discovery of DNA aptamers targeting SARS-CoV-2 nucleocapsid protein and protein-binding epitopes for label-free COVID-19 diagnostics

Suttinee Poolsup et al.

Summary: This study aimed to develop a label-free optical aptasensor using a novel single-stranded DNA aptamer to detect the SARS-CoV-2 nucleocapsid (N) protein. The tNSP3 aptamer was identified to bind the N protein of different variants with high affinity. Utilizing tNSP3, the N protein could be detected in human saliva with a limit of detection of 4.5 nM. Mass spectrometry analysis and molecular dynamics simulation provided insights into the binding mechanism of tNSP3 with the N protein. Overall, this aptamer demonstrated potential as an analytical tool for COVID-19 diagnosis.

MOLECULAR THERAPY-NUCLEIC ACIDS (2023)

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Article Chemistry, Multidisciplinary

Electrical Detection Assay Based on Programmable Nucleic Acid Probe for Efficient Single-Nucleotide Polymorphism Identification

Yun Zhang et al.

Summary: The development of an efficient and sensitive on-site nucleic acid testing method with SNP identification capability is urgently needed due to the large-scale pandemic and fast evolution of SARS-CoV-2 variants. In this study, a multiplexed electrical detection assay based on a PNprobe functionalized FET biosensor was developed for highly sensitive and specific detection and discrimination of SARS-CoV-2 variants. The assay achieved simultaneous detection and identification of key mutations of seven SARS-CoV-2 variants within 15 minutes, with an identification accuracy of 97.1% for 70 simulated throat swab samples.

ACS SENSORS (2023)

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Article Chemistry, Analytical

A polyethylene glycol enhanced ligation-triggered self-priming isothermal amplification for the detection of SARS-CoV-2 D614G mutation

Luxin Yu et al.

Summary: We developed a PEG enhanced ligation-triggered self-priming isothermal amplification method for detecting the D614G mutation in S-glycoprotein of SARS-CoV-2. This method utilizes molecular crowding environment and hairpin probes to achieve efficient ligation and amplification. The resulting DNA products containing target sequence domains can be monitored in real-time fluorescence signaling. The proposed assay has a wide linear range and high sensitivity, making it a potential method for monitoring mutations in SARS-CoV-2 variants.

TALANTA (2023)

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Article Chemistry, Analytical

Synthesis and characterization of Au-decorated graphene oxide nanocomposite for magneto-electrochemical detection of SARS-CoV-2 nucleocapsid gene

Pravanjan Malla et al.

Summary: This article describes a rapid and sensitive electrochemical assay for quantifying the CoV-2 nucleocapsid gene using magnetic nanocomposite and DNA sandwich probes, with a detection limit of 0.37 fM.

TALANTA (2023)

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Article Multidisciplinary Sciences

Development of a rapid and ultra-sensitive RNA:DNA hybrid immunocapture based biosensor for visual detection of SARS-CoV-2 RNA

Anusree Dey et al.

Summary: This study presents a novel biosensor method for visual detection of viral RNA using an anti-RNA:DNA hybrid antibody, coupled with transcription-mediated isothermal RNA amplification. The method demonstrates rapid, sensitive, specific, and simple detection of viral RNA, with a total turnaround time of an hour. The technique shows high sensitivity and specificity when compared to a commercial gold standard assay.

PNAS NEXUS (2023)

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Article Biochemical Research Methods

Coupling immuno-magnetic capture with LC-MS/MS(MRM) as a sensitive, reliable, and specific assay for SARS-CoV-2 identification from clinical samples

Ofir Schuster et al.

Summary: A combined approach of immuno-magnetic viral isolation and mass spectrometry analysis was developed for the identification of SARS-CoV-2. The method demonstrated high reliability, specificity, and sensitivity, and could potentially serve as a complementary assay to RT-qPCR. This methodology can also be applied to other viruses.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

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Article Multidisciplinary Sciences

Performance of the Abbott SARS-CoV-2 IgG serological assay in South African 2 patients

Sarika Jugwanth et al.

Summary: This study aimed to validate the performance criteria of the Abbott assay for SARS-CoV2 IgG detection in the South African population. The sensitivity of the Abbott and Alinity assays was found to be 69.5% and 64.8%, respectively, compared to RT-qPCR. The specificity of the Architect and Alinity assays was 95% and 90.3%, respectively. When compared to in-house ELISA assay, the sensitivity of the Abbott and Alinity assays was 94.7% and 92.5%, respectively. Based on the findings, testing for IgG after 14 days is recommended in South Africa.

PLOS ONE (2022)

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Review Chemistry, Analytical

AGREEprep - Analytical greenness metric for sample preparation

Wojciech Wojnowski et al.

Summary: AGREEprep is a metric tool that prioritizes sample preparation, evaluating factors such as solvent, material, and reagent choices, waste generation, and energy consumption to calculate the final assessment score. The assessment procedure utilizes intuitive software to generate an easy-to-read information pictogram showing overall performance and threat structure.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2022)

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Article Infectious Diseases

Detection of SARS-CoV-2 by antigen ELISA test is highly swayed by viral load and sample storage condition

Nihad Adnan et al.

Summary: This study investigated the correlation of Ct value, storage temperature, and conditions with SARS-CoV-2 diagnosis using a newly developed ELISA system. Results showed that the ELISA system had highest sensitivity for samples with Ct <= 30 and stored at -80 degrees C, with specificity ranging between 98.3% and 100%. Early infection phase diagnosis and lower temperature preservation of samples are crucial for rapid antigen ELISA tests.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2022)

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Article Multidisciplinary Sciences

SARS-CoV-2 detection by targeting four loci of viral genome using graphene oxide and gold nanoparticle DNA biosensor

Arman Amani Babadi et al.

Summary: The current COVID-19 pandemic poses a serious threat to public health and calls for the development of effective detection methods. This research presents a dual-platform DNA biosensor that utilizes colorimetric assay and SERS technique for simultaneous detection of SARS-CoV-2 and its new variants, providing high sensitivity and rapid results.

SCIENTIFIC REPORTS (2022)

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Review Genetics & Heredity

Real-Time Polymerase Chain Reaction: Current Techniques, Applications, and Role in COVID-19 Diagnosis

I. Made Artika et al.

Summary: The real-time polymerase chain reaction (PCR) method, known for its quantitative, accurate, sensitive, and rapid nature, has been successfully used in detecting the first SARS-CoV-2 cases. It is widely applied in various fields such as gene expression analysis, pathogen detection and quantification, and has become the gold standard for COVID-19 diagnosis.

GENES (2022)

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Article Medicine, General & Internal

Fuzzy-Based PROMETHEE Method for Performance Ranking of SARS-CoV-2 IgM Antibody Tests

Ayse Arikan et al.

Summary: This study evaluated the parameters of FDA-authorized SARS-CoV-2 IgM antibody tests and ranked them according to their performance levels. The results can assist decision-makers in selecting the appropriate antibody test for managing COVID-19.

DIAGNOSTICS (2022)

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Review Medicine, General & Internal

Lateral Flow Immunoassays for SARS-CoV-2

Geik Yong Ang et al.

Summary: The continued circulation of SARS-CoV-2 and potential emergence of more virulent variants pose challenges to healthcare systems. Nucleic acid-based diagnostic tests are limited by specialized equipment requirements, particularly in low-resource settings. The availability of lateral flow immunoassays (LFIs) is highly appealing due to their rapid, low-cost, equipment-free nature. LFIs can serve as diagnostic tools for detecting SARS-CoV-2 antigen and measuring host immune response.

DIAGNOSTICS (2022)

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Article Chemistry, Analytical

Electrochemical Biosensor for SARS-CoV-2 cDNA Detection Using AuPs-Modified 3D-Printed Graphene Electrodes

Luiz R. G. Silva et al.

Summary: A low-cost and disposable graphene polylactic (G-PLA) 3D-printed electrode modified with gold particles (AuPs) was developed to detect the cDNA of SARS-CoV-2 and creatinine, a potential biomarker for COVID-19. The study demonstrated that this approach offers a fast, simple, and cost-effective analysis.

BIOSENSORS-BASEL (2022)

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Article Biochemical Research Methods

Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination

Grace Kenny et al.

Summary: This study validates a quantitative multiplex serologic assay for measuring antibody responses to SARS-CoV-2, showing high sensitivity and specificity, and strong correlation with commercially available assays.

JOURNAL OF IMMUNOLOGICAL METHODS (2022)

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Article Public, Environmental & Occupational Health

A comparative study on the efficiency of commercial reverse transcriptase-Polymerase chain reaction kits for the detection of severe acute respiratory syndrome coronavirus 2 infections

Gopinath Ramalingam et al.

Summary: This study aimed to investigate commercially available RT-PCR kits for the detection of SARS-CoV-2 infections. The performance of seven different RT-PCR kits was analyzed, and it was found that the sensitivities and batch effects were slightly different for the detection of SARS-CoV-2 in nasopharyngeal swab specimens. It is recommended to examine COVID-19 kits using the currently employed kits in routine diagnosis for better efficiency.

INDIAN JOURNAL OF PUBLIC HEALTH (2022)

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Review Cell Biology

Antibody detection assays for COVID-19 diagnosis: an early overview

Sarfaraz Ahmad Ejazi et al.

Summary: Researchers worldwide are intensifying efforts to control the spread of COVID-19, with a focus on finding alternative testing methods. The rapid development of immunological tests is proving to be effective in diagnosing viral infections, offering a potential solution to the challenges posed by high prices and lengthy procedures of current molecular tests.

IMMUNOLOGY AND CELL BIOLOGY (2021)

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Review Biotechnology & Applied Microbiology

Detection technologies and recent developments in the diagnosis of COVID-19 infection

Praveen Rai et al.

Summary: COVID-19 is a disease caused by SARS-CoV-2 that has spread globally, requiring collaborative efforts for accurate diagnosis and prevention. While RT-qPCR detection is considered the gold standard for early virus detection, challenges such as technical complexity and limited applicability have led to the development of portable POC tests.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2021)

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Review Virology

Serological assays and host antibody detection in coronavirus-related disease diagnosis

Sayeh Dowlatshahi et al.

Summary: Coronaviruses are a family of viral pathogens that infect both birds and mammals, including humans. Seven human coronaviruses have been recognized, with three causing severe diseases. Various diagnostic techniques have been developed to detect these viruses.

ARCHIVES OF VIROLOGY (2021)

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Article Multidisciplinary Sciences

A new SYBR Green real-time PCR to detect SARS-CoV-2

D. R. Marinowic et al.

Summary: A low-cost, highly specific method for SARS-CoV-2 detection has been successfully developed using the SYBR Green RT-PCR method, with the ability to screen out negative cases and high safety and efficacy. Optimization of experimental parameters achieved high specificity of PCR products, providing technical support for large-scale screening.

SCIENTIFIC REPORTS (2021)

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Review Biology

Genetic analysis of the 2019 coronavirus pandemic with from real-time reverse transcriptase polymerase chain reaction

Abdullah Farasani

Summary: Corona viruses, particularly the novel coronavirus (SARS-CoV-2) that caused the COVID-19 pandemic, have had a significant impact on global society in 2020. The importance of thorough description of international spread of the virus is crucial for healthcare strategies and preventing potential outbreaks. The use of Real-time reverse transcriptase polymerase chain reaction (RT-PCR) for diagnosing active SARS-CoV-2 infections has become essential in monitoring and controlling the pandemic.

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021)

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Article Medical Laboratory Technology

A rapid lateral flow immunoassay strip for detection of SARS-CoV-2 antigen using latex microspheres

Lin Shen et al.

Summary: In third-world countries, the lateral flow immunoassay strip (LFIA) may be a better method for detecting SARS-CoV-2, and this study developed a highly specific LFIA with a sensitivity and specificity of 98.22% and 97.93%, respectively.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

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Article Chemistry, Multidisciplinary

Specific and Rapid SARS-CoV-2 Identification Based on LC-MS/MS Analysis

Ofir Schuster et al.

Summary: A novel method for SARS-CoV-2 identification based on mass spectrometry was presented, which involves a multistep procedure for specific peptide marker selection and liquid chromatography coupled to high-resolution mass spectrometry. The developed assay is rapid, simple, and specific, achieving 94% concordance with the gold standard RT-qPCR method when applied to clinical samples. This MS-based assay provides a complementary approach to RT-qPCR for SARS-CoV-2 detection, showing potential for clinical applications.

ACS OMEGA (2021)

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Review Engineering, Electrical & Electronic

Potential Microfluidic Devices for COVID-19 Antibody Detection at Point-of-Care (POC): A Review

Muhammad Tayyab et al.

Summary: The COVID-19 pandemic has drastically impacted the global economy and society. Testing for genetic material and antibodies of SARS-CoV-2 is crucial for stratifying populations into different groups to safely reopen society. This review highlights the current diagnostic and surveillance technologies for detecting SARS-CoV-2 antibodies and emphasizes the potential of microfluidic sensors for commercialization in low-resource and Point-of-Care settings.

IEEE SENSORS JOURNAL (2021)

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Article Multidisciplinary Sciences

Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens

Karel Bezstarosti et al.

Summary: This study utilized targeted mass spectrometry to detect SARS-CoV-2 proteins with high sensitivity and accuracy in clinical specimens, presenting a new potential tool for COVID-19 diagnostics.

PLOS ONE (2021)

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Article Multidisciplinary Sciences

Time course of the sensitivity and specificity of anti-SARS-CoV-2 IgM and IgG antibodies for symptomatic COVID-19 in Japan

Yuki Nakano et al.

Summary: This study focused on investigating the time courses of SARS-CoV-2 IgM and IgG titers in patients in Japan, finding that the sensitivity of antibody tests varied significantly at different time points after symptom onset, with increased accuracy as the days since onset increased.

SCIENTIFIC REPORTS (2021)

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Article Biology

Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis

Andreas Hober et al.

Summary: A scalable analytical approach using LC-MS technology has been developed to accurately detect SARS-CoV-2 viral proteins, showing strong correlation with RT-PCR results. This method has rapid turnaround times and high sensitivity and specificity, making it suitable for future pandemic monitoring and control.

ELIFE (2021)

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Article Biology

A Multiallelic Molecular Beacon-Based Real-Time RT-PCR Assay for the Detection of SARS-CoV-2

Andreas C. Chrysostomou et al.

Summary: Emerging infectious viruses that easily mutate present challenges for diagnostics, but a real-time RT-PCR detection assay has been developed to specifically detect the genes of SARS-CoV-2, with potential for adaptation to other rapidly mutating pathogens.

LIFE-BASEL (2021)

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Article Biochemical Research Methods

A rapid and reliable liquid chromatography/mass spectrometry method for SARS-CoV-2 analysis from gargle solutions and saliva

Marc Kipping et al.

Summary: The study presents a rapid LC-MS/MS method for detecting and quantifying SARS-CoV-2 nucleoprotein in gargle solutions and saliva with improved sample preparation protocol. It aims to advance diagnostic tools for identifying and monitoring SARS-CoV-2 infections in a routine clinical setting using LC-MS/MS methods.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

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Review Biochemistry & Molecular Biology

Biochemical composition, transmission and diagnosis of SARS-CoV-2

Rajeshy Ahirwar et al.

Summary: COVID-19, caused by SARS-CoV-2, is a life-threatening respiratory infection declared a pandemic in March 2020 due to its rapid global spread. Despite various technological advancements in testing and diagnosis, effective antiretroviral drugs and widespread vaccination are necessary to curb the escalating pandemic.

BIOSCIENCE REPORTS (2021)

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Article Biophysics

Ultra-fast and recyclable DNA biosensor for point-of-care detection of SARS-CoV-2 (COVID-19)

Chuljin Hwang et al.

Summary: This study introduces a label-free DNA capacitive biosensor for SARS-CoV-2 detection, offering real-time, low-cost, and high-throughput screening of nucleic acid samples. The biosensor validates specific DNA sequences' hybridization signals through comprehensive physicochemical analytical techniques, demonstrating significant sensitivity in detecting the conserved region of the SARS-CoV-2 RdRp gene.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Medicine, General & Internal

A mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimens

Santosh Renuse et al.

Summary: The study developed a method to detect SARS-CoV-2 viral antigen from nasopharyngeal swab samples using immunoaffinity purification and high resolution mass spectrometry. The optimized assay showed 98% sensitivity and 100% specificity, demonstrating potential for clinical deployment in diagnostic laboratories.

EBIOMEDICINE (2021)

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Article Chemistry, Multidisciplinary

Complementary green analytical procedure index (ComplexGAPI) and software

Justyna Plotka-Wasylka et al.

Summary: The study proposed a new metric based on GAC attributes for evaluating the green nature of analytical procedures. This metric expands on the green analytical procedure index by adding additional fields related to processes performed before the analytical procedure, and was used to evaluate analytical protocols for determining pesticides in urine samples. It is expected to gain attention and acceptance from the chemical community.

GREEN CHEMISTRY (2021)

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Article Chemistry, Multidisciplinary

Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients

Bart Van Puyvelde et al.

Summary: The rapid spread of COVID-19 is attributed to rising population density and global mobility, making accurate monitoring of the disease essential for policy responses. The current reliance on RT-PCR for diagnosis has limitations due to reagent shortages, prompting the development of an alternative test using mass spectrometry to detect SARS-CoV-2 proteins. The Cov-MS consortium and Digital Incubator were established to enhance the applicability and accessibility of this new diagnostic approach.

JACS AU (2021)

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Review Virology

Diagnostic accuracy of serological tests and kinetics of severe acute respiratory syndrome coronavirus 2 antibody: A systematic review and meta-analysis

Daniel Mekonnen et al.

Summary: This study evaluated the diagnostic test accuracy of SARS-COV-2 serological tests and the kinetics of antibody positivity through systematic review and meta-analysis. Results showed that CLIA assays targeting antibodies against RBD had the highest sensitivity and varied over time. The antibody positivity rate increased with days post-symptom onset, but decreased when transitioning from acute phase to convalescent phase.

REVIEWS IN MEDICAL VIROLOGY (2021)

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Article Infectious Diseases

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

Victor M. Corman et al.

EUROSURVEILLANCE (2020)

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Review Virology

The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients

Yan-Chao Li et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

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Article Chemistry, Multidisciplinary

Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based Biosensor

Giwan Seo et al.

ACS NANO (2020)

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Article Chemistry, Analytical

Rapid and Sensitive Detection of anti-SARS-CoV-2 IgG, Using Lanthanide-Doped Nanoparticles-Based Lateral Flow Immunoassay

Zhenhua Chen et al.

ANALYTICAL CHEMISTRY (2020)

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Review Medicine, General & Internal

Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus 2 A Narrative Review

Matthew P. Cheng et al.

ANNALS OF INTERNAL MEDICINE (2020)

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Article Medical Laboratory Technology

Diagnostic performances and thresholds: The key to harmonization in serological SARS-CoV-2 assays?

Mario Plebani et al.

CLINICA CHIMICA ACTA (2020)

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Letter Medical Laboratory Technology

Assessment of immune response to SARS-CoV-2 with fully automated MAGLUMI 2019-nCoV IgG and IgM chemiluminescence immunoassays

Giuseppe Lippi et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2020)

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Article Allergy

SARS-CoV-2 antibody testing-questions to be asked

Mustafa K. Oezcueruemez et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

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Article Immunology

A Peptide-Based Magnetic Chemiluminescence Enzyme Immunoassay for Serological Diagnosis of Coronavirus Disease 2019

Xue-fei Cai et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

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Article Biotechnology & Applied Microbiology

RT-LAMP for rapid diagnosis of coronavirus SARS-CoV-2

Wei E. Huang et al.

MICROBIAL BIOTECHNOLOGY (2020)

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Article Medicine, Research & Experimental

Development of a Laboratory-safe and Low-cost Detection Protocol for SARS-CoV-2 of the Coronavirus Disease 2019 (COVID-19)

Joungha Won et al.

Experimental Neurobiology (2020)

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Review Pathology

Review of Current Advances in Serologic Testing for COVID-19

Andrea P. Espejo et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2020)

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Article Chemistry, Analytical

AGREE-Analytical GREEnness Metric Approach and Software

Francisco Pena-Pereira et al.

ANALYTICAL CHEMISTRY (2020)

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Letter Medical Laboratory Technology

Antibody Profiles in Mild and Severe Cases of COVID-19

Zhi-Li Liu et al.

CLINICAL CHEMISTRY (2020)

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Article Infectious Diseases

Clinical evaluation of serological IgG antibody response on the Abbott Architect for established SARS-CoV-2 infection

K. L. Chew et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

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Article Infectious Diseases

Monitoring antibody response following SARS-CoV-2 infection: diagnostic efficiency of 4 automated immunoassays

Fleur Wolff et al.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2020)

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Article Infectious Diseases

Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak

Dachuan Lin et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2020)

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Article Biochemistry & Molecular Biology

Optimization of primer sets and detection protocols for SARS-CoV-2 of coronavirus disease 2019 (COVID-19) using PCR and real-time PCR

Myungsun Park et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

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Review Infectious Diseases

Current Status of Laboratory Diagnosis for COVID-19: A Narrative Review

Antonio Russo et al.

INFECTION AND DRUG RESISTANCE (2020)

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Article Virology

Comparison of the diagnostic sensitivity of SARS-CoV-2 nucleoprotein and glycoprotein-based antibody tests

Carolin Schnurra et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Article Virology

Comparison of four new commercial serologic assays for determination of SARS-CoV-2 IgG

Alexander Krüttgen et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Article Virology

Evaluation of the EUROIMMUN Anti-SARS-CoV-2 ELISA Assay for detection of IgA and IgG antibodies

Kathleen G. Beavis et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Review Medicine, General & Internal

COVID-19 Serological Tests: How Well Do They Actually Perform?

Abdi Ghaffari et al.

DIAGNOSTICS (2020)

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Article Pathology

Humoral Immune Response to SARS-CoV-2 Comparative Clinical Performance of Seven Commercial Serology Tests

Pauline H. Herroelen et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2020)

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Article Biochemical Research Methods

Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients

Christian Ihling et al.

JOURNAL OF PROTEOME RESEARCH (2020)

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Article Chemistry, Analytical

Development of a Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of SARS-CoV-2 Spike Glycoprotein and Nucleoprotein

Lisa H. Cazares et al.

ANALYTICAL CHEMISTRY (2020)

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Review Biophysics

Diagnostics for SARS-CoV-2 detection: A comprehensive review of the FDA-EUA COVID-19 testing landscape

Neeraja Ravi et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Article Multidisciplinary Sciences

An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment

Corine H. GeurtsvanKessel et al.

NATURE COMMUNICATIONS (2020)

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Article Virology

Comparative evaluation of SARS-CoV-2 IgG assays in India

Susmita Chaudhuri et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Article Medical Laboratory Technology

Performance verification of anti-SARS-CoV-2-specific antibody detection by using four chemiluminescence immunoassay systems

Yafang Wan et al.

ANNALS OF CLINICAL BIOCHEMISTRY (2020)

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COVID-19 diagnostic testing: Technology perspective

Meng Xu et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2020)

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Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

Karina Helena Morais Cardozo et al.

NATURE COMMUNICATIONS (2020)

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Six decades of lateral flow immunoassay: from determining metabolic markers to diagnosing COVID-19

Boris G. Andryukov

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Meta-analysis of diagnostic performance of serology tests for COVID-19: impact of assay design and post-symptom-onset intervals

Hongyu Wang et al.

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A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Hanbi Kim et al.

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Aromatic aldehydes as selective fluorogenic derivatizing agents for α-dicarbonyl compounds. Application to HPLC analysis of some advanced glycation end products and oxidative stress biomarkers in human serum

Mahmoud H. El-Maghrabey et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)

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Article Chemistry, Analytical

A new tool for the evaluation of the analytical procedure: Green Analytical Procedure Index

J. Plotka-Wasylka

TALANTA (2018)

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Review Chemistry, Analytical

Multiplex Lateral Flow Immunoassay: An Overview of Strategies towards High-throughput Point-of-Need Testing

Laura Anfossi et al.

BIOSENSORS-BASEL (2018)

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Review Immunology

Chemiluminescent immunoassay technology: what does it change in autoantibody detection?

Luigi Cinquanta et al.

AUTOIMMUNITY HIGHLIGHTS (2017)

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Article Medical Laboratory Technology

Enzyme Immunoassay (EIA)/Enzyme-Linked Immunosorbent Assay (ELISA)

RM Lequin

CLINICAL CHEMISTRY (2005)

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Article Microbiology

GeneScan reverse transcription-PCR assay for detection of six common respiratory viruses in young children hospitalized with acute respiratory illness

DD Erdman et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2003)

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