Luminescent covalent organic cages with a C3-symmetric structure for effective enantioseparation

In recent years, incredible endeavors have been devoted to the design and self-assembly of discrete covalent organic cages with expanding intricacy and functionality. They have excellent applications in different fields, but their applications in enantioselective separation have not been fully developed. Here, a pair of chiral cages with custom cavities based on the unique rigid structure of 1,10-binaphthol (binol) were selected for effective enantioseparation. Meanwhile chiral resolution tests reveal diverse host-guest stereoselectivity towards different chiral molecules.

Automated summary

In recent years, there have been significant efforts in the design and self-assembly of discrete covalent organic cages. These cages have various applications, but their potential in enantioselective separation has not been fully explored. This study focuses on the use of chiral cages with custom cavities for effective enantioseparation and reveals diverse host-guest stereoselectivity towards different chiral molecules.